我在我的一个项目中有这样的代码:

from datetime import datetime
## datetime.timezone works in newer versions of python
try:
    from datetime import timezone
    utc_tz = timezone.utc
except:
    import pytz
    utc_tz = pytz.utc

def _to_utc_date_string(ts):
    # type (Union[date,datetime]]) -> str
    """coerce datetimes to UTC (assume localtime if nothing is given)"""
    if (isinstance(ts, datetime)):
        try:
            ## in python 3.6 and higher, ts.astimezone() will assume a
            ## naive timestamp is localtime (and so do we)
            ts = ts.astimezone(utc_tz)
        except:
            ## in python 2.7 and 3.5, ts.astimezone() will fail on
            ## naive timestamps, but we'd like to assume they are
            ## localtime
            import tzlocal
            ts = tzlocal.get_localzone().localize(ts).astimezone(utc_tz)
    return ts.strftime("%Y%m%dT%H%M%SZ")

def local_to_utc(t):
    secs = time.mktime(t)
    return time.gmtime(secs)

def utc_to_local(t):
    secs = calendar.timegm(t)
    return time.localtime(secs)

来源:http://feihonghsu.blogspot.com/2008/02/converting-from-local-time-to-utc.html

来自bd808的示例用法:如果您的源是一个datetime。Datetime对象t，调用as:

local_to_utc(t.timetuple())

简单地说，要将任何datetime日期转换为UTC时间:

from datetime import datetime

def to_utc(date):
    return datetime(*date.utctimetuple()[:6])

让我们用一个例子来解释。首先，我们需要从字符串中创建一个datetime:

>>> date = datetime.strptime("11 Feb 2011 17:33:54 -0800", "%d %b %Y %H:%M:%S %z")

然后，我们可以调用函数:

>>> to_utc(date)
datetime.datetime(2011, 2, 12, 1, 33, 54)

函数如何一步步工作:

>>> date.utctimetuple()
time.struct_time(tm_year=2011, tm_mon=2, tm_mday=12, tm_hour=1, tm_min=33, tm_sec=54, tm_wday=5, tm_yday=43, tm_isdst=0)
>>> date.utctimetuple()[:6]
(2011, 2, 12, 1, 33, 54)
>>> datetime(*date.utctimetuple()[:6])
datetime.datetime(2011, 2, 12, 1, 33, 54)

下面是Python3.9中本地zoneinfo模块的示例:

from datetime import datetime
from zoneinfo import ZoneInfo

# Get timezone we're trying to convert from
local_tz = ZoneInfo("America/New_York")
# UTC timezone
utc_tz = ZoneInfo("UTC")

dt = datetime.strptime("2021-09-20 17:20:00","%Y-%m-%d %H:%M:%S")
dt = dt.replace(tzinfo=local_tz)
dt_utc = dt.astimezone(utc_tz)

print(dt.strftime("%Y-%m-%d %H:%M:%S"))
print(dt_utc.strftime("%Y-%m-%d %H:%M:%S"))

在转换的时区不反映系统本地时区的情况下，这可能比仅使用dt.astimezone()更可取。不必依赖外部库也很好。

注意:这可能在Windows系统上不起作用，因为zoneinfo依赖于可能不存在的IANA数据库。tzdata包可以作为解决方案安装。它是第一方包，但不在标准库中。

我在这里找到了另一个问题的最佳答案。它只使用python内置库，不需要您输入本地时区(在我的情况下是一个要求)

import time
import calendar

local_time = time.strptime("2018-12-13T09:32:00.000", "%Y-%m-%dT%H:%M:%S.%f")
local_seconds = time.mktime(local_time)
utc_time = time.gmtime(local_seconds)

我在这里重新发布答案，因为这个问题在谷歌中弹出，而不是根据搜索关键字链接的问题。

import time

import datetime

def Local2UTC(LocalTime):

    EpochSecond = time.mktime(LocalTime.timetuple())
    utcTime = datetime.datetime.utcfromtimestamp(EpochSecond)

    return utcTime

>>> LocalTime = datetime.datetime.now()

>>> UTCTime = Local2UTC(LocalTime)

>>> LocalTime.ctime()

'Thu Feb  3 22:33:46 2011'

>>> UTCTime.ctime()

'Fri Feb  4 05:33:46 2011'