这个问题没有太多细节，所以我采取的方法是用最简单的解释来解决这个问题：去掉标点符号。

请注意，所提供的解决方案不考虑收缩词（例如，you are）或连字符词（例如肛门保留）。。。这是关于它们是否应该被视为标点符号的争论。。。也不能解释非英语字符集或类似的东西。。。因为问题中没有提到这些细节。有人认为空格是标点符号，这在技术上是正确的。。。但对我来说，这在当前问题的背景下毫无意义。

# using lambda
''.join(filter(lambda c: c not in string.punctuation, s))

# using list comprehension
''.join('' if c in string.punctuation else c for c in s)

with open('one.txt','r')as myFile:

    str1=myFile.read()

    print(str1)


    punctuation = ['(', ')', '?', ':', ';', ',', '.', '!', '/', '"', "'"] 

for i in punctuation:

        str1 = str1.replace(i," ") 
        myList=[]
        myList.extend(str1.split(" "))
print (str1) 
for i in myList:

    print(i,end='\n')
    print ("____________")

我喜欢使用这样的函数：

def scrub(abc):
    while abc[-1] is in list(string.punctuation):
        abc=abc[:-1]
    while abc[0] is in list(string.punctuation):
        abc=abc[1:]
    return abc

正则表达式很简单，如果你知道的话。

import re
s = "string. With. Punctuation?"
s = re.sub(r'[^\w\s]','',s)

这是我写的一个函数。它不是很有效，但很简单，您可以添加或删除任何您想要的标点符号：

def stripPunc(wordList):
    """Strips punctuation from list of words"""
    puncList = [".",";",":","!","?","/","\\",",","#","@","$","&",")","(","\""]
    for punc in puncList:
        for word in wordList:
            wordList=[word.replace(punc,'') for word in wordList]
    return wordList

显然，我无法对所选答案进行编辑，所以这里有一个适用于Python3的更新。在进行非平凡转换时，转换方法仍然是最有效的选择。

上面的@Brian为最初的繁重工作做出了贡献。感谢@ddejohn对原始测试的改进建议。

#!/usr/bin/env python3

"""Determination of most efficient way to remove punctuation in Python 3.

Results in Python 3.8.10 on my system using the default arguments:

set       : 51.897
regex     : 17.901
translate :  2.059
replace   : 13.209
"""

import argparse
import re
import string
import timeit

parser = argparse.ArgumentParser()
parser.add_argument("--filename", "-f", default=argparse.__file__)
parser.add_argument("--iterations", "-i", type=int, default=10000)
opts = parser.parse_args()
with open(opts.filename) as fp:
    s = fp.read()
exclude = set(string.punctuation)
table = str.maketrans("", "", string.punctuation)
regex = re.compile(f"[{re.escape(string.punctuation)}]")

def test_set(s):
    return "".join(ch for ch in s if ch not in exclude)

def test_regex(s):  # From Vinko's solution, with fix.
    return regex.sub("", s)

def test_translate(s):
    return s.translate(table)

def test_replace(s):  # From S.Lott's solution
    for c in string.punctuation:
        s = s.replace(c, "")
    return s

opts = dict(globals=globals(), number=opts.iterations)
solutions = "set", "regex", "translate", "replace"
for solution in solutions:
    elapsed = timeit.timeit(f"test_{solution}(s)", **opts)
    print(f"{solution:<10}: {elapsed:6.3f}")