我在寻找一个非常简单的解决方案。这是我得到的：

import re 

s = "string. With. Punctuation?" 
s = re.sub(r'[\W\s]', ' ', s)

print(s)
'string  With  Punctuation '

myString.translate(None, string.punctuation)

为了方便使用，我总结了Python 2和Python 3中从字符串中删除标点符号的注意事项。有关详细说明，请参阅其他答案。

Python 2

import string

s = "string. With. Punctuation?"
table = string.maketrans("","")
new_s = s.translate(table, string.punctuation)      # Output: string without punctuation

Python 3

import string

s = "string. With. Punctuation?"
table = str.maketrans(dict.fromkeys(string.punctuation))  # OR {key: None for key in string.punctuation}
new_s = s.translate(table)                          # Output: string without punctuation

对于严肃的自然语言处理（NLP），您应该让像SpaCy这样的库通过标记化处理标点符号，然后您可以根据需要手动调整。

例如，您希望如何处理单词中的连字符？例外情况，如缩写？开始和结束引号？URL？在NLP中，将“let’s”这样的收缩分隔为“let”和“s”以进行进一步处理通常很有用。

试试那个：）

regex.sub(r'\p{P}','', s)

# FIRST METHOD
# Storing all punctuations in a variable    
punctuation='!?,.:;"\')(_-'
newstring ='' # Creating empty string
word = raw_input("Enter string: ")
for i in word:
     if(i not in punctuation):
                  newstring += i
print ("The string without punctuation is", newstring)

# SECOND METHOD
word = raw_input("Enter string: ")
punctuation = '!?,.:;"\')(_-'
newstring = word.translate(None, punctuation)
print ("The string without punctuation is",newstring)


# Output for both methods
Enter string: hello! welcome -to_python(programming.language)??,
The string without punctuation is: hello welcome topythonprogramminglanguage