我还没有尝试过，但是pyiso8601承诺支持这一点。

各向异性8601应该处理这个问题。它还理解时区，Python 2和Python 3，并且它还合理地覆盖了ISO 8601的其余部分，如果你需要它的话。

import aniso8601
aniso8601.parse_datetime('2007-03-04T21:08:12')

Arrow看起来很有希望:

>>> import arrow
>>> arrow.get('2014-11-13T14:53:18.694072+00:00').datetime
datetime.datetime(2014, 11, 13, 14, 53, 18, 694072, tzinfo=tzoffset(None, 0))

Arrow是一个Python库，提供了一种明智、智能的方式来创建、操作、格式化和转换日期和时间。Arrow简单，轻量级，受到moment.js和请求的启发。

Isodate似乎有最完整的支持。

这里有一个超级简单的方法来做这种转换。 无需解析，也不需要额外的库。 它干净、简单、快捷。

import datetime
import time

################################################
#
# Takes the time (in seconds),
#   and returns a string of the time in ISO8601 format.
# Note: Timezone is UTC
#
################################################

def TimeToISO8601(seconds):
   strKv = datetime.datetime.fromtimestamp(seconds).strftime('%Y-%m-%d')
   strKv = strKv + "T"
   strKv = strKv + datetime.datetime.fromtimestamp(seconds).strftime('%H:%M:%S')
   strKv = strKv +"Z"
   return strKv

################################################
#
# Takes a string of the time in ISO8601 format,
#   and returns the time (in seconds).
# Note: Timezone is UTC
#
################################################

def ISO8601ToTime(strISOTime):
   K1 = 0
   K2 = 9999999999
   K3 = 0
   counter = 0
   while counter < 95:
     K3 = (K1 + K2) / 2
     strK4 = TimeToISO8601(K3)
     if strK4 < strISOTime:
       K1 = K3
     if strK4 > strISOTime:
       K2 = K3
     counter = counter + 1
   return K3

################################################
#
# Takes a string of the time in ISO8601 (UTC) format,
#   and returns a python DateTime object.
# Note: returned value is your local time zone.
#
################################################

def ISO8601ToDateTime(strISOTime):
   return time.gmtime(ISO8601ToTime(strISOTime))


#To test:
Test = "2014-09-27T12:05:06.9876"
print ("The test value is: " + Test)
Ans = ISO8601ToTime(Test)
print ("The answer in seconds is: " + str(Ans))
print ("And a Python datetime object is: " + str(ISO8601ToDateTime(Test)))

因为ISO 8601允许出现多种可选冒号和破折号，基本上是CCYY-MM-DDThh:mm:ss[Z|(+|-)hh:mm]。如果希望使用strptime，则需要先去掉这些变量。

目标是生成一个UTC datetime对象。

如果你只想要一个适用于UTC的Z后缀的基本情况，比如2016-06-29T19:36:29.3453Z:

datetime.datetime.strptime(timestamp.translate(None, ':-'), "%Y%m%dT%H%M%S.%fZ")

如果您想处理时区偏移，如2016-06-29T19:36:29.3453-0400或2008-09-03T20:56:35.450686+05:00，请使用以下方法。这将把所有变量转换为没有变量分隔符的内容，如20080903T205635.450686+0500，使其更一致/更容易解析。

import re
# This regex removes all colons and all
# dashes EXCEPT for the dash indicating + or - utc offset for the timezone
conformed_timestamp = re.sub(r"[:]|([-](?!((\d{2}[:]\d{2})|(\d{4}))$))", '', timestamp)
datetime.datetime.strptime(conformed_timestamp, "%Y%m%dT%H%M%S.%f%z" )

如果您的系统不支持%z strptime指令(您会看到类似ValueError: 'z'是一个格式为'%Y%m%dT%H% m% S.%f%z'的错误指令)，那么您需要手动从z (UTC)偏移时间。注意%z可能无法在Python版本< 3的系统上运行，因为它依赖于C库支持，而C库支持因系统/Python构建类型(即Jython、Cython等)而异。

import re
import datetime

# This regex removes all colons and all
# dashes EXCEPT for the dash indicating + or - utc offset for the timezone
conformed_timestamp = re.sub(r"[:]|([-](?!((\d{2}[:]\d{2})|(\d{4}))$))", '', timestamp)

# Split on the offset to remove it. Use a capture group to keep the delimiter
split_timestamp = re.split(r"([+|-])",conformed_timestamp)
main_timestamp = split_timestamp[0]
if len(split_timestamp) == 3:
    sign = split_timestamp[1]
    offset = split_timestamp[2]
else:
    sign = None
    offset = None

# Generate the datetime object without the offset at UTC time
output_datetime = datetime.datetime.strptime(main_timestamp +"Z", "%Y%m%dT%H%M%S.%fZ" )
if offset:
    # Create timedelta based on offset
    offset_delta = datetime.timedelta(hours=int(sign+offset[:-2]), minutes=int(sign+offset[-2:]))

    # Offset datetime with timedelta
    output_datetime = output_datetime + offset_delta