使用Swift 3并采用最快的黑客方法，您可以使用扩展来改进代码:

extension UITableViewCell {

    var isSeparatorHidden: Bool {
        get {
            return self.separatorInset.right != 0
        }
        set {
            if newValue {
                self.separatorInset = UIEdgeInsetsMake(0, self.bounds.size.width, 0, 0)
            } else {
                self.separatorInset = UIEdgeInsetsMake(0, 0, 0, 0)
            }
        }
    }

}

然后，当你配置单元格时:

func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {
    let cell = collectionView.dequeueReusableCell(withReuseIdentifier: "identifier", for: indexPath)
    switch indexPath.row {
       case 3:
          cell.isSeparatorHidden = true
       default:
          cell.isSeparatorHidden = false
    }
    return cell
}

func tableView(_ tableView: UITableView, didSelectRowAt indexPath: IndexPath) {
    let cell = tableView.cellForRow(at: indexPath)
    if cell.isSeparatorHidden { 
       // do stuff
    }
}

迅速:

public func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {

    ...

    // remove separator for last cell
    cell.separatorInset = indexPath.row < numberOfRowsInSection-1
        ? tableView.separatorInset
        : UIEdgeInsets(top: 0, left: tableView.bounds.size.width, bottom: 0, right: 0)

    return cell
}

objective - c:

- (UITableViewCell *)tableView:(UITableView *)tableView
     cellForRowAtIndexPath:(NSIndexPath *)indexPath {

    ...

    // remove separator for last cell
    cell.separatorInset = (indexPath.row < numberOfRowsInSection-1)
        ? tableView.separatorInset
        : UIEdgeInsetsMake(0.f, tableView.bounds.size.width, 0.f, 0.f);

    return cell;
}

使用这个子类，set separatorInset在iOS 9.2.1中不起作用，内容会被压缩。

@interface NSPZeroMarginCell : UITableViewCell

@property (nonatomic, assign) BOOL separatorHidden;

@end

@implementation NSPZeroMarginCell

- (void) layoutSubviews {
    [super layoutSubviews];

    for (UIView *view in  self.subviews) {
        if (![view isKindOfClass:[UIControl class]]) {
            if (CGRectGetHeight(view.frame) < 3) {
                view.hidden = self.separatorHidden;
            }
        }
    }
}

@end

https://gist.github.com/liruqi/9a5add4669e8d9cd3ee9

在viewDidLoad中添加这一行:

self.tableView.separatorColor = [UIColor clearColor];

在cellForRowAtIndexPath中:

适用于iOS低版本

if(indexPath.row != self.newCarArray.count-1){
    UIImageView *line = [[UIImageView alloc] initWithFrame:CGRectMake(0, 44, 320, 2)];
    line.backgroundColor = [UIColor redColor];
    [cell addSubview:line];
}

适用于iOS 7以上版本(包括iOS 8)

if (indexPath.row == self.newCarArray.count-1) {
    cell.separatorInset = UIEdgeInsetsMake(0.f, cell.bounds.size.width, 0.f, 0.f);
}

在UITableViewDataSource的cellForRowAtIndexPath方法中

迅速:

if indexPath.row == {your row number} {
    cell.separatorInset = UIEdgeInsets(top: 0, left: 0, bottom: 0, right: .greatestFiniteMagnitude)
}

or :

cell.separatorInset = UIEdgeInsetsMake(0, 0, 0, UIScreen.main.bounds.width)

对于默认保证金:

cell.separatorInset = UIEdgeInsetsMake(0, tCell.layoutMargins.left, 0, 0)

显示端到端的分隔符

cell.separatorInset = .zero

objective - c:

if (indexPath.row == {your row number}) {
    cell.separatorInset = UIEdgeInsetsMake(0.0f, 0.0f, 0.0f, CGFLOAT_MAX);
}

我不相信这种方法在任何情况下都适用于动态单元格……

if (indexPath.row == self.newCarArray.count-1) {
  cell.separatorInset = UIEdgeInsetsMake(0.f, cell.bounds.size.width, 0.f, 0.f);
}

不管你在哪个tableview方法中为动态单元格做这件事，你改变了inset属性的单元格总是有inset属性设置，现在每次它被退出队列时，都会导致缺少行分隔符的狂暴…除非你自己改变。

这样的方法对我很有效:

if indexPath.row == franchises.count - 1 {
  cell.separatorInset = UIEdgeInsetsMake(0, cell.contentView.bounds.width, 0, 0)
} else {
  cell.separatorInset = UIEdgeInsetsMake(0, 0, cell.contentView.bounds.width, 0)
}

这样你就可以在每次加载时更新数据结构状态