- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {

       NSString *cellId = @"cell";
       UITableViewCell *cell = [tableView dequeueReusableCellWithIdentifier:cellId];
       NSInteger lastRowIndexInSection = [tableView numberOfRowsInSection:indexPath.section] - 1;

       if (row == lastRowIndexInSection) {
              CGFloat halfWidthOfCell = cell.frame.size.width / 2;
              cell.separatorInset = UIEdgeInsetsMake(0, halfWidthOfCell, 0, halfWidthOfCell);
       }
}

对于iOS7或更高版本，更简洁的方法是使用INFINITY而不是硬编码的值。当屏幕旋转时，您不必担心更新单元格。

if (indexPath.row == <row number>) {
    cell.separatorInset = UIEdgeInsetsMake(0, INFINITY, 0, 0);
}

试试下面的代码，也许能帮你解决问题

- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {

   NSString* reuseIdentifier = @"Contact Cell";

    UITableViewCell* cell = [tableView dequeueReusableCellWithIdentifier:reuseIdentifier];
    if (nil == cell) {
        cell = [[UITableViewCell alloc] initWithStyle:UITableViewCellStyleDefault reuseIdentifier:reuseIdentifier];
if (indexPath.row != 10) {//Specify the cell number
        cell.backgroundView.backgroundColor = [UIColor colorWithPatternImage:[UIImage imageNamed:@"bgWithLine.png"]];

} else {
        cell.backgroundView.backgroundColor = [UIColor colorWithPatternImage:[UIImage imageNamed:@"bgWithOutLine.png"]];

}

    }

    return cell;
}

in viewDidLoad() {    

   tableView.separatorStyle = UITableViewCellSeparatorStyle.None 

}

当我使用扩展和调用layoutSubviews()立即更新布局视图时，它为我工作。

extension UITableViewCell {

    func removeSeparator() {
        separatorInset = UIEdgeInsetsMake(0, bounds.size.width, 0, 0)
    }
}

override func layoutSubviews() {
    super.layoutSubviews()

    removeSeparator()
}

迅速:

public func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {

    ...

    // remove separator for last cell
    cell.separatorInset = indexPath.row < numberOfRowsInSection-1
        ? tableView.separatorInset
        : UIEdgeInsets(top: 0, left: tableView.bounds.size.width, bottom: 0, right: 0)

    return cell
}

objective - c:

- (UITableViewCell *)tableView:(UITableView *)tableView
     cellForRowAtIndexPath:(NSIndexPath *)indexPath {

    ...

    // remove separator for last cell
    cell.separatorInset = (indexPath.row < numberOfRowsInSection-1)
        ? tableView.separatorInset
        : UIEdgeInsetsMake(0.f, tableView.bounds.size.width, 0.f, 0.f);

    return cell;
}