- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {

       NSString *cellId = @"cell";
       UITableViewCell *cell = [tableView dequeueReusableCellWithIdentifier:cellId];
       NSInteger lastRowIndexInSection = [tableView numberOfRowsInSection:indexPath.section] - 1;

       if (row == lastRowIndexInSection) {
              CGFloat halfWidthOfCell = cell.frame.size.width / 2;
              cell.separatorInset = UIEdgeInsetsMake(0, halfWidthOfCell, 0, halfWidthOfCell);
       }
}

当我使用扩展和调用layoutSubviews()立即更新布局视图时，它为我工作。

extension UITableViewCell {

    func removeSeparator() {
        separatorInset = UIEdgeInsetsMake(0, bounds.size.width, 0, 0)
    }
}

override func layoutSubviews() {
    super.layoutSubviews()

    removeSeparator()
}

使用Swift 3并采用最快的黑客方法，您可以使用扩展来改进代码:

extension UITableViewCell {

    var isSeparatorHidden: Bool {
        get {
            return self.separatorInset.right != 0
        }
        set {
            if newValue {
                self.separatorInset = UIEdgeInsetsMake(0, self.bounds.size.width, 0, 0)
            } else {
                self.separatorInset = UIEdgeInsetsMake(0, 0, 0, 0)
            }
        }
    }

}

然后，当你配置单元格时:

func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {
    let cell = collectionView.dequeueReusableCell(withReuseIdentifier: "identifier", for: indexPath)
    switch indexPath.row {
       case 3:
          cell.isSeparatorHidden = true
       default:
          cell.isSeparatorHidden = false
    }
    return cell
}

func tableView(_ tableView: UITableView, didSelectRowAt indexPath: IndexPath) {
    let cell = tableView.cellForRow(at: indexPath)
    if cell.isSeparatorHidden { 
       // do stuff
    }
}

对于iOS7或更高版本，更简洁的方法是使用INFINITY而不是硬编码的值。当屏幕旋转时，您不必担心更新单元格。

if (indexPath.row == <row number>) {
    cell.separatorInset = UIEdgeInsetsMake(0, INFINITY, 0, 0);
}

在viewDidLoad中添加这一行:

self.tableView.separatorColor = [UIColor clearColor];

在cellForRowAtIndexPath中:

适用于iOS低版本

if(indexPath.row != self.newCarArray.count-1){
    UIImageView *line = [[UIImageView alloc] initWithFrame:CGRectMake(0, 44, 320, 2)];
    line.backgroundColor = [UIColor redColor];
    [cell addSubview:line];
}

适用于iOS 7以上版本(包括iOS 8)

if (indexPath.row == self.newCarArray.count-1) {
    cell.separatorInset = UIEdgeInsetsMake(0.f, cell.bounds.size.width, 0.f, 0.f);
}

- (UITableViewCell *)tableView:(UITableView *)tableView cellForRowAtIndexPath:(NSIndexPath *)indexPath {

       NSString *cellId = @"cell";
       UITableViewCell *cell = [tableView dequeueReusableCellWithIdentifier:cellId];
       NSInteger lastRowIndexInSection = [tableView numberOfRowsInSection:indexPath.section] - 1;

       if (row == lastRowIndexInSection) {
              CGFloat halfWidthOfCell = cell.frame.size.width / 2;
              cell.separatorInset = UIEdgeInsetsMake(0, halfWidthOfCell, 0, halfWidthOfCell);
       }
}