在使用iOS 8.4的Swift中:

/*
    Tells the delegate that the table view is about to draw a cell for a particular row. (optional)
*/
override func tableView(tableView: UITableView,
                        willDisplayCell cell: UITableViewCell,
                        forRowAtIndexPath indexPath: NSIndexPath)
{
    if indexPath.row == 3 {
        // Hiding separator line for only one specific UITableViewCell
        cell.separatorInset = UIEdgeInsetsMake(0, cell.bounds.size.width, 0, 0)
    }
}

Note: this snippet above will work on UITableView using dynamic cells. The only problem that you can encounter is when you use static cells with categories, a separator type different than none and a grouped style for the table view. In fact, in this particular case it will not hide the last cell of each category. For overcoming that, the solution that I found was to set the cell separator (through IB) to none and then creating and adding manually (through code) your line view to each cell. For an example, please check the snippet below:

/*
Tells the delegate that the table view is about to draw a cell for a particular row. (optional)
*/
override func tableView(tableView: UITableView,
    willDisplayCell cell: UITableViewCell,
    forRowAtIndexPath indexPath: NSIndexPath)
{
    // Row 2 at Section 2
    if indexPath.row == 1 && indexPath.section == 1 {
        // Hiding separator line for one specific UITableViewCell
        cell.separatorInset = UIEdgeInsetsMake(0, cell.bounds.size.width, 0, 0)

        // Here we add a line at the bottom of the cell (e.g. here at the second row of the second section).
        let additionalSeparatorThickness = CGFloat(1)
        let additionalSeparator = UIView(frame: CGRectMake(0,
            cell.frame.size.height - additionalSeparatorThickness,
            cell.frame.size.width,
            additionalSeparatorThickness))
        additionalSeparator.backgroundColor = UIColor.redColor()
        cell.addSubview(additionalSeparator)
    }
}

使用Swift 3并采用最快的黑客方法，您可以使用扩展来改进代码:

extension UITableViewCell {

    var isSeparatorHidden: Bool {
        get {
            return self.separatorInset.right != 0
        }
        set {
            if newValue {
                self.separatorInset = UIEdgeInsetsMake(0, self.bounds.size.width, 0, 0)
            } else {
                self.separatorInset = UIEdgeInsetsMake(0, 0, 0, 0)
            }
        }
    }

}

然后，当你配置单元格时:

func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {
    let cell = collectionView.dequeueReusableCell(withReuseIdentifier: "identifier", for: indexPath)
    switch indexPath.row {
       case 3:
          cell.isSeparatorHidden = true
       default:
          cell.isSeparatorHidden = false
    }
    return cell
}

func tableView(_ tableView: UITableView, didSelectRowAt indexPath: IndexPath) {
    let cell = tableView.cellForRow(at: indexPath)
    if cell.isSeparatorHidden { 
       // do stuff
    }
}

在UITableViewDataSource的cellForRowAtIndexPath方法中

迅速:

if indexPath.row == {your row number} {
    cell.separatorInset = UIEdgeInsets(top: 0, left: 0, bottom: 0, right: .greatestFiniteMagnitude)
}

or :

cell.separatorInset = UIEdgeInsetsMake(0, 0, 0, UIScreen.main.bounds.width)

对于默认保证金:

cell.separatorInset = UIEdgeInsetsMake(0, tCell.layoutMargins.left, 0, 0)

显示端到端的分隔符

cell.separatorInset = .zero

objective - c:

if (indexPath.row == {your row number}) {
    cell.separatorInset = UIEdgeInsetsMake(0.0f, 0.0f, 0.0f, CGFLOAT_MAX);
}

在Swift 3, Swift 4和Swift 5中，你可以像这样写一个UITableViewCell扩展:

extension UITableViewCell {
  func separator(hide: Bool) {
    separatorInset.left = hide ? bounds.size.width : 0
  }
}

然后你可以这样使用它(当cell是你的cell实例时):

cell.separator(hide: false) // Shows separator 
cell.separator(hide: true) // Hides separator

将表格视图单元格的宽度赋为左插入值比赋给它一些随机数更好。因为在某些屏幕尺寸中，也许不是现在，但将来你的分隔符仍然是可见的因为这个随机数可能不够。此外，在iPad横屏模式下，你不能保证你的分隔符总是不可见。

iphone的宽度是320。因此，在单元格属性中为separatorInset设置左右值，大于320的一半。

使用这个子类，set separatorInset在iOS 9.2.1中不起作用，内容会被压缩。

@interface NSPZeroMarginCell : UITableViewCell

@property (nonatomic, assign) BOOL separatorHidden;

@end

@implementation NSPZeroMarginCell

- (void) layoutSubviews {
    [super layoutSubviews];

    for (UIView *view in  self.subviews) {
        if (![view isKindOfClass:[UIControl class]]) {
            if (CGRectGetHeight(view.frame) < 3) {
                view.hidden = self.separatorHidden;
            }
        }
    }
}

@end

https://gist.github.com/liruqi/9a5add4669e8d9cd3ee9