这应该做的技巧，只是使用OS模块列出，然后删除!

import os
DIR = os.list('Folder')
for i in range(len(DIR)):
    os.remove('Folder'+chr(92)+i)

为我工作过，有任何问题请告诉我!

import os, shutil
folder = '/path/to/folder'
for filename in os.listdir(folder):
    file_path = os.path.join(folder, filename)
    try:
        if os.path.isfile(file_path) or os.path.islink(file_path):
            os.unlink(file_path)
        elif os.path.isdir(file_path):
            shutil.rmtree(file_path)
    except Exception as e:
        print('Failed to delete %s. Reason: %s' % (file_path, e))

使用操作系统。Python 3.6+中的scandir和上下文管理器协议:

import os
import shutil

with os.scandir(target_dir) as entries:
    for entry in entries:
        if entry.is_dir() and not entry.is_symlink():
            shutil.rmtree(entry.path)
        else:
            os.remove(entry.path)

Python的早期版本:

import os
import shutil

# Gather directory contents
contents = [os.path.join(target_dir, i) for i in os.listdir(target_dir)]

# Iterate and remove each item in the appropriate manner
[shutil.rmtree(i) if os.path.isdir(i) and not os.path.islink(i) else os.remove(i) for i in contents]

如果您正在使用*nix系统，为什么不利用system命令呢?

import os
path = 'folder/to/clean'
os.system('rm -rf %s/*' % path)

注:以防有人对我的答案投了反对票，我在这里有一些事情要解释。

Everyone likes short 'n' simple answers. However, sometimes the reality is not so simple. Back to my answer. I know shutil.rmtree() could be used to delete a directory tree. I've used it many times in my own projects. But you must realize that the directory itself will also be deleted by shutil.rmtree(). While this might be acceptable for some, it's not a valid answer for deleting the contents of a folder (without side effects). I'll show you an example of the side effects. Suppose that you have a directory with customized owner and mode bits, where there are a lot of contents. Then you delete it with shutil.rmtree() and rebuild it with os.mkdir(). And you'll get an empty directory with default (inherited) owner and mode bits instead. While you might have the privilege to delete the contents and even the directory, you might not be able to set back the original owner and mode bits on the directory (e.g. you're not a superuser). Finally, be patient and read the code. It's long and ugly (in sight), but proven to be reliable and efficient (in use).

这里有一个冗长而丑陋，但可靠而有效的解决方案。

它解决了一些其他答案没有解决的问题:

它正确地处理符号链接，包括不对符号链接调用shutil.rmtree()(如果它链接到一个目录，它将通过os.path.isdir()测试;甚至os.walk()的结果也包含符号链接目录)。 它可以很好地处理只读文件。

下面是代码(唯一有用的函数是clear_dir()):

import os
import stat
import shutil


# http://stackoverflow.com/questions/1889597/deleting-directory-in-python
def _remove_readonly(fn, path_, excinfo):
    # Handle read-only files and directories
    if fn is os.rmdir:
        os.chmod(path_, stat.S_IWRITE)
        os.rmdir(path_)
    elif fn is os.remove:
        os.lchmod(path_, stat.S_IWRITE)
        os.remove(path_)


def force_remove_file_or_symlink(path_):
    try:
        os.remove(path_)
    except OSError:
        os.lchmod(path_, stat.S_IWRITE)
        os.remove(path_)


# Code from shutil.rmtree()
def is_regular_dir(path_):
    try:
        mode = os.lstat(path_).st_mode
    except os.error:
        mode = 0
    return stat.S_ISDIR(mode)


def clear_dir(path_):
    if is_regular_dir(path_):
        # Given path is a directory, clear its content
        for name in os.listdir(path_):
            fullpath = os.path.join(path_, name)
            if is_regular_dir(fullpath):
                shutil.rmtree(fullpath, onerror=_remove_readonly)
            else:
                force_remove_file_or_symlink(fullpath)
    else:
        # Given path is a file or a symlink.
        # Raise an exception here to avoid accidentally clearing the content
        # of a symbolic linked directory.
        raise OSError("Cannot call clear_dir() on a symbolic link")

对此，最好使用os.walk()。

Os.listdir()并不区分文件和目录，你很快就会遇到麻烦，试图解除这些链接。这里有一个使用os.walk()递归删除目录的好例子，并提示了如何使其适应您的环境。