使用操作系统。Python 3.6+中的scandir和上下文管理器协议:

import os
import shutil

with os.scandir(target_dir) as entries:
    for entry in entries:
        if entry.is_dir() and not entry.is_symlink():
            shutil.rmtree(entry.path)
        else:
            os.remove(entry.path)

Python的早期版本:

import os
import shutil

# Gather directory contents
contents = [os.path.join(target_dir, i) for i in os.listdir(target_dir)]

# Iterate and remove each item in the appropriate manner
[shutil.rmtree(i) if os.path.isdir(i) and not os.path.islink(i) else os.remove(i) for i in contents]

使用下面的方法删除目录的内容，而不是目录本身:

import os
import shutil

def remove_contents(path):
    for c in os.listdir(path):
        full_path = os.path.join(path, c)
        if os.path.isfile(full_path):
            os.remove(full_path)
        else:
            shutil.rmtree(full_path)

要删除目录及其子目录中的所有文件，而不删除文件夹本身，只需执行以下操作:

import os
mypath = "my_folder" #Enter your path here
for root, dirs, files in os.walk(mypath, topdown=False):
    for file in files:
        os.remove(os.path.join(root, file))

    # Add this block to remove folders
    for dir in dirs:
        os.rmdir(os.path.join(root, dir))

# Add this line to remove the root folder at the end
os.rmdir(mypath)

作为一个在线人士:

import os

# Python 2.7
map( os.unlink, (os.path.join( mydir,f) for f in os.listdir(mydir)) )

# Python 3+
list( map( os.unlink, (os.path.join( mydir,f) for f in os.listdir(mydir)) ) )

一个更健壮的文件和目录的解决方案是(2.7):

def rm(f):
    if os.path.isdir(f): return os.rmdir(f)
    if os.path.isfile(f): return os.unlink(f)
    raise TypeError, 'must be either file or directory'

map( rm, (os.path.join( mydir,f) for f in os.listdir(mydir)) )

扩展mhawke的回答，这是我所实现的。它删除文件夹的所有内容，但不删除文件夹本身。在Linux上测试了文件、文件夹和符号链接，应该也能在Windows上运行。

import os
import shutil

for root, dirs, files in os.walk('/path/to/folder'):
    for f in files:
        os.unlink(os.path.join(root, f))
    for d in dirs:
        shutil.rmtree(os.path.join(root, d))

import os, shutil
folder = '/path/to/folder'
for filename in os.listdir(folder):
    file_path = os.path.join(folder, filename)
    try:
        if os.path.isfile(file_path) or os.path.islink(file_path):
            os.unlink(file_path)
        elif os.path.isdir(file_path):
            shutil.rmtree(file_path)
    except Exception as e:
        print('Failed to delete %s. Reason: %s' % (file_path, e))