谢谢大家的帮助，这是我尝试的代码，这是为我工作

   UILabel *instructions = [[UILabel alloc]initWithFrame:CGRectMake(10, 225, 300, 180)];
   NSString *text = @"First take clear picture and then try to zoom in to fit the ";
   instructions.text = text;
   instructions.textAlignment = UITextAlignmentCenter;
   instructions.lineBreakMode = NSLineBreakByWordWrapping;
   [instructions setTextColor:[UIColor grayColor]];

   CGSize expectedLabelSize = [text sizeWithFont:instructions.font 
                                constrainedToSize:instructions.frame.size
                                    lineBreakMode:UILineBreakModeWordWrap];

    CGRect newFrame = instructions.frame;
    newFrame.size.height = expectedLabelSize.height;
    instructions.frame = newFrame;
    instructions.numberOfLines = 0;
    [instructions sizeToFit];
    [self addSubview:instructions];

一行是克里斯的答案是错的。

newFrame.size.height = maximumLabelSize.height;

应该是

newFrame.size.height = expectedLabelSize.height;

除此之外，这是正确的解决方案。

以下是分类版本:

UILabel + AutoSize.h #进口

@interface UILabel (AutoSize)

- (void) autosizeForWidth: (int) width;

@end

UILabel + AutoSize。m

#import "UILabel+AutoSize.h"

@implementation UILabel (AutoSize)

- (void) autosizeForWidth: (int) width {
    self.lineBreakMode = UILineBreakModeWordWrap;
    self.numberOfLines = 0;
    CGSize maximumLabelSize = CGSizeMake(width, FLT_MAX);
    CGSize expectedLabelSize = [self.text sizeWithFont:self.font constrainedToSize:maximumLabelSize lineBreakMode:self.lineBreakMode];
    CGRect newFrame = self.frame;
    newFrame.size.height = expectedLabelSize.height;
    self.frame = newFrame;
}

@end

当自动布局被启用时，调整大小不工作:)

对于那些迁移到iOS 8的人，这里有一个Swift的类扩展:

extension UILabel {

    func autoresize() {
        if let textNSString: NSString = self.text {
            let rect = textNSString.boundingRectWithSize(CGSizeMake(self.frame.size.width, CGFloat.max),
                options: NSStringDrawingOptions.UsesLineFragmentOrigin,
                attributes: [NSFontAttributeName: self.font],
                context: nil)
            self.frame = CGRectMake(self.frame.origin.x, self.frame.origin.y, self.frame.size.width, rect.height)
        }
    }

}

这是使用Objective-c获取UILabel Height的一行代码:

labelObj.numberOfLines = 0;
CGSize neededSize = [labelObj sizeThatFits:CGSizeMake(screenWidth, CGFLOAT_MAX)];

使用.height你会得到标签的高度，如下所示:

neededSize.height