您应该使用整数主键。如果你需要电子邮件列是唯一的，为什么不简单地在该列上设置一个唯一索引呢?

使用电子邮件地址作为主键的缺点:

Slower when doing joins. Any other record with a posted foreign key now has a larger value, taking up more disk space. (Given the cost of disk space today, this is probably a trivial issue, except to the extent that the record now takes longer to read. See #1.) An email address could change, which forces all records using this as a foreign key to be updated. As email address don't change all that often, the performance problem is probably minor. The bigger problem is that you have to make sure to provide for it. If you have to write the code, this is more work and introduces the possibility of bugs. If your database engine supports "on update cascade", it's a minor issue.

使用电邮地址作主键的优点:

You may be able to completely eliminate some joins. If all you need from the "master record" is the email address, then with an abstract integer key you would have to do a join to retrieve it. If the key is the email address, then you already have it and the join is unnecessary. Whether this helps you any depends on how often this situation comes up. When you are doing ad hoc queries, it's easy for a human being to see what master record is being referenced. This can be a big help when trying to track down data problems. You almost certainly will need an index on the email address anyway, so making it the primary key eliminates one index, thus improving the performance of inserts as they now have only one index to update instead of two.

在我看来，这两种情况都不是十拿九稳的。当有实用的键时，我倾向于使用自然键，因为它们更容易使用，而且在大多数情况下，缺点并不太重要。

使用GUID作为主键…这样，当你执行INSERT操作时，你就可以从程序中生成它，而不需要从服务器获取响应来找出主键是什么。它在所有表和数据库中都是唯一的，如果有一天你截断了表，自动增量被重置为1，你不必担心会发生什么。

你的同事是对的:使用一个自动递增的整数作为你的主键。

您可以在应用程序级别实现电子邮件唯一性，或者您可以将电子邮件地址列标记为惟一，并在该列上添加索引。

将字段添加为唯一字段只会在插入到该表时花费字符串比较的成本，而不会在执行连接和外键约束检查时花费字符串比较成本。

当然，您必须注意，在数据库级别向应用程序添加任何约束都可能导致应用程序变得不灵活。在仅仅因为应用程序需要某个字段是唯一的或非空的，就将它设置为“唯一的”或“非空的”之前，一定要充分考虑。

似乎没有人提到一个可能的问题，即电子邮件地址可能被视为隐私。如果电子邮件地址是主键，那么个人资料页面的URL很可能类似于..../Users/my@email.com。如果不想暴露用户的电子邮件地址怎么办?您必须找到其他一些识别用户的方法，可能是通过一个唯一的整数值来生成像..../Users/1这样的url。那么你最终会得到一个唯一的整数值。

不要使用电子邮件地址为主键，保持电子邮件的唯一性，但不要使用它为主键，使用用户id或用户名为主键