Xcode 11+， Swift 5。

根据@WantToKnow的回答，我解决了我的问题，我准备了视频和代码

import UIKit

class ViewController: UIViewController {

    //
    let scrollView: UIScrollView = {
        
        let sv = UIScrollView()
        sv.translatesAutoresizingMaskIntoConstraints = false
        return sv
    }()
    
    let lipsumLbl: UILabel = { // you can use here any of your subview
        
        let lbl = UILabel()
        lbl.translatesAutoresizingMaskIntoConstraints = false
        lbl.text = """
        Lorem ipsum dolor sit amet, consectetur adipiscing elit. Fusce eleifend nisi sit amet mi aliquet, ut efficitur risus pellentesque. Phasellus nulla justo, scelerisque ut libero id, aliquet ullamcorper lectus. Integer id iaculis nibh. Duis feugiat mi vitae magna tincidunt, vitae consequat dui tempor. Donec blandit urna nec urna volutpat, sit amet sagittis massa fringilla. Pellentesque luctus erat nec dui luctus, sed maximus urna fermentum. Nullam purus nibh, cursus vel ex nec, pulvinar lobortis leo. Proin ac libero rhoncus, bibendum lorem sed, congue sapien. Donec commodo, est non mollis malesuada, nisi massa tempus ipsum, a varius quam lorem vitae nunc.
        
        Cras scelerisque nisi dolor, in gravida ex ornare a. Interdum et malesuada fames ac ante ipsum primis in faucibus. Maecenas vitae nisl id erat sollicitudin accumsan sit amet viverra sapien. Etiam scelerisque vulputate ante. Donec magna nibh, pharetra sed pretium ac, feugiat sit amet mi. Vestibulum in ipsum vitae dui vehicula pulvinar eget ut lectus. Fusce sagittis a elit ac elementum. Fusce iaculis nunc odio, at fermentum dolor varius et. Suspendisse consectetur congue massa non gravida. Sed id elit vitae nulla aliquam euismod. Pellentesque accumsan risus dolor, eu cursus nibh semper id.
        
        Vestibulum vel tortor tellus. Suspendisse potenti. Pellentesque id sapien eu augue placerat dictum. Fusce tempus ligula at diam lacinia congue in ut metus. Maecenas volutpat tellus in tellus maximus imperdiet. Integer dignissim condimentum lorem, id luctus nisi maximus at. Nulla pretium, est sit amet mollis eleifend, tellus nulla viverra dolor, ac feugiat massa risus a lectus. Pellentesque ut pulvinar urna, blandit gravida ipsum. Nullam volutpat arcu nec fringilla auctor. Integer egestas enim commodo, faucibus neque ac, rutrum magna. Vivamus tincidunt rutrum auctor. Cras at rutrum felis. Fusce elementum lorem ut pharetra venenatis.
        """
        lbl.textColor = .darkGray
        lbl.font = UIFont.systemFont(ofSize: 16)
        lbl.numberOfLines = 0
        return lbl
    }()
    
    //======================================================================//
    //
    // MARK:- viewDidLoad
    //
    override func viewDidLoad() {
        super.viewDidLoad()
        
        setupViews()
        setupAutoLayout()
    }
    
    func setupViews() {
        
        title = "ScrollView Demo"
        view.backgroundColor = .white
        view.addSubview(scrollView)
        scrollView.addSubview(lipsumLbl)
    }
    
    func setupAutoLayout() {
        
        scrollView.leftAnchor.constraint(equalTo: view.leftAnchor).isActive = true
        scrollView.rightAnchor.constraint(equalTo: view.rightAnchor).isActive = true
        scrollView.topAnchor.constraint(equalTo: view.topAnchor).isActive = true
        scrollView.bottomAnchor.constraint(equalTo: view.bottomAnchor).isActive = true
        
        lipsumLbl.topAnchor.constraint(equalTo: scrollView.topAnchor).isActive = true
        lipsumLbl.leftAnchor.constraint(equalTo: view.leftAnchor).isActive = true
        lipsumLbl.rightAnchor.constraint(equalTo: view.rightAnchor).isActive = true
        lipsumLbl.bottomAnchor.constraint(equalTo: scrollView.bottomAnchor).isActive = true
    }
}

输出:

那些在uiscrollview而不是滚动中挣扎的人只是用你上一个视图的底部布局(在你的内容视图内部)来设置你的内容视图的底部约束。不要忘记删除中心Y的约束。

其余所有约束与上面定义的相同。Scrollview只关心从它的内容视图获取最大高度，我们将它设置为最后一个视图的底部约束，这意味着Scrollview将自动改变它的内容偏移量。

在我的例子中，最后一个视图是可用的，没有线属性= 0(自动调整它的高度取决于它的内容)，所以它动态增加可用的高度，最终我们的可滚动区域增加，因为可用的底部布局与我们的内容视图的底部对齐，这迫使scrollview增加它的内容偏移。

在我的情况下，我收到了不正确的内容大小和内容大小模糊的问题在iPad，但在iPhone的情况下工作。我在故事板中做了以下更改来解决这个问题。

在UIView中添加scrollview并添加约束前置，上，后，下到0,0,0,0。 设置滚动视图的高度根据要求，例如。One hundred. 添加UIView到滚动视图，并添加约束领先，顶部，尾部和底部0,0,0,0和对齐中心(X)和中心(Y)约束。 在滚动视图的尺寸检查器中取消选择“内容布局指南”。

见下图:内容视图以滚动视图垂直和水平集中。 你有歧义错误，总是确保从你的内容视图添加到scrollview的两个是1).按钮空间到容器。2)尾随空间到屏幕截图中突出显示的约束，

这些约束的意思是在滚动中，你可以在你的内容视图高度或宽度后滚动多少。

它可能对你有帮助。

Xcode 11 +。

使用自动布局的最简单方法:

Add UIScrollView and pin it 0,0,0,0 to superview (or your desired size) Add container of UIView type inside ScrollView, pin it 0,0,0,0 to all 4 sides and center it horizontally and vertically. In size inspector of container, change bottom and align center Y priority to 250. (for horizontal scroll change trailing and align center X) Add all views that you need into said container (UIView). Don't forget to set the bottom constraint on the lowest view. Select the UIScrollView, select the size inspector and deselect Content Layout Guides.