为了用轮询和最小依赖来观察单个文件，下面是一个完整的例子，基于Deestan的回答(上面):

import os
import sys 
import time

class Watcher(object):
    running = True
    refresh_delay_secs = 1

    # Constructor
    def __init__(self, watch_file, call_func_on_change=None, *args, **kwargs):
        self._cached_stamp = 0
        self.filename = watch_file
        self.call_func_on_change = call_func_on_change
        self.args = args
        self.kwargs = kwargs

    # Look for changes
    def look(self):
        stamp = os.stat(self.filename).st_mtime
        if stamp != self._cached_stamp:
            self._cached_stamp = stamp
            # File has changed, so do something...
            print('File changed')
            if self.call_func_on_change is not None:
                self.call_func_on_change(*self.args, **self.kwargs)

    # Keep watching in a loop        
    def watch(self):
        while self.running: 
            try: 
                # Look for changes
                time.sleep(self.refresh_delay_secs) 
                self.look() 
            except KeyboardInterrupt: 
                print('\nDone') 
                break 
            except FileNotFoundError:
                # Action on file not found
                pass
            except: 
                print('Unhandled error: %s' % sys.exc_info()[0])

# Call this function each time a change happens
def custom_action(text):
    print(text)

watch_file = 'my_file.txt'

# watcher = Watcher(watch_file)  # simple
watcher = Watcher(watch_file, custom_action, text='yes, changed')  # also call custom action function
watcher.watch()  # start the watch going

这是对Tim Goldan脚本的另一种修改，它运行在unix类型上，并通过使用dict (file=>time)为文件修改添加了一个简单的监控器。

用法:whatvername .py path_to_dir_to_watch

#!/usr/bin/env python

import os, sys, time

def files_to_timestamp(path):
    files = [os.path.join(path, f) for f in os.listdir(path)]
    return dict ([(f, os.path.getmtime(f)) for f in files])

if __name__ == "__main__":

    path_to_watch = sys.argv[1]
    print('Watching {}..'.format(path_to_watch))

    before = files_to_timestamp(path_to_watch)

    while 1:
        time.sleep (2)
        after = files_to_timestamp(path_to_watch)

        added = [f for f in after.keys() if not f in before.keys()]
        removed = [f for f in before.keys() if not f in after.keys()]
        modified = []

        for f in before.keys():
            if not f in removed:
                if os.path.getmtime(f) != before.get(f):
                    modified.append(f)

        if added: print('Added: {}'.format(', '.join(added)))
        if removed: print('Removed: {}'.format(', '.join(removed)))
        if modified: print('Modified: {}'.format(', '.join(modified)))

        before = after

下面是一个示例，用于观察每秒写入不超过一行但通常要少得多的输入文件。目标是将最后一行(最近的写入)追加到指定的输出文件。我从我的一个项目中复制了这个，只是删除了所有不相关的行。你必须填写或修改缺失的符号。

from PyQt5.QtCore import QFileSystemWatcher, QSettings, QThread
from ui_main_window import Ui_MainWindow   # Qt Creator gen'd 

class MainWindow(QMainWindow, Ui_MainWindow):
    def __init__(self, parent=None):
        QMainWindow.__init__(self, parent)
        Ui_MainWindow.__init__(self)
        self._fileWatcher = QFileSystemWatcher()
        self._fileWatcher.fileChanged.connect(self.fileChanged)

    def fileChanged(self, filepath):
        QThread.msleep(300)    # Reqd on some machines, give chance for write to complete
        # ^^ About to test this, may need more sophisticated solution
        with open(filepath) as file:
            lastLine = list(file)[-1]
        destPath = self._filemap[filepath]['dest file']
        with open(destPath, 'a') as out_file:               # a= append
            out_file.writelines([lastLine])

当然，并不是严格要求包含QMainWindow类。您可以单独使用QFileSystemWatcher。

你试过用看门狗吗?

Python API库和shell实用程序来监视文件系统事件。 目录监视变得很容易 一个跨平台的API。 一个shell工具，用于在目录更改时运行命令。 用一个简单的例子开始快速入门…

如果轮询对您来说足够好，我只观察“修改的时间”文件统计是否发生变化。阅读方法:

os.stat(filename).st_mtime

(还要注意，Windows本机更改事件解决方案并不在所有情况下都有效，例如在网络驱动器上。)

import os

class Monkey(object):
    def __init__(self):
        self._cached_stamp = 0
        self.filename = '/path/to/file'

    def ook(self):
        stamp = os.stat(self.filename).st_mtime
        if stamp != self._cached_stamp:
            self._cached_stamp = stamp
            # File has changed, so do something...

如果您想要一个多平台解决方案，那么请检查QFileSystemWatcher。 下面是一个示例代码(未消毒):

from PyQt4 import QtCore

@QtCore.pyqtSlot(str)
def directory_changed(path):
    print('Directory Changed!!!')

@QtCore.pyqtSlot(str)
def file_changed(path):
    print('File Changed!!!')

fs_watcher = QtCore.QFileSystemWatcher(['/path/to/files_1', '/path/to/files_2', '/path/to/files_3'])

fs_watcher.connect(fs_watcher, QtCore.SIGNAL('directoryChanged(QString)'), directory_changed)
fs_watcher.connect(fs_watcher, QtCore.SIGNAL('fileChanged(QString)'), file_changed)