您可以为每个布局逐个设置自定义字体，只需通过传递根视图从每个布局调用一个函数即可。首先，创建一个像这样访问字体对象的单例方法

 public class Font {
    private static Font font;
    public Typeface ROBO_LIGHT;

    private Font() {

    }

    public static Font getInstance(Context context) {
        if (font == null) {
            font = new Font();
            font.init(context);
        }
        return font;

    }

    public void init(Context context) {

        ROBO_LIGHT = Typeface.createFromAsset(context.getAssets(),
                "Roboto-Light.ttf");
    }

}

你可以在上面的类中定义不同的字体，现在定义一个字体助手类来应用字体:

   public class FontHelper {

    private static Font font;

    public static void applyFont(View parentView, Context context) {

        font = Font.getInstance(context);

        apply((ViewGroup)parentView);

    }

    private static void apply(ViewGroup parentView) {
        for (int i = 0; i < parentView.getChildCount(); i++) {

            View view = parentView.getChildAt(i);

//You can add any view element here on which you want to apply font 

            if (view instanceof EditText) {

                ((EditText) view).setTypeface(font.ROBO_LIGHT);

            }
            if (view instanceof TextView) {

                ((TextView) view).setTypeface(font.ROBO_LIGHT);

            }

            else if (view instanceof ViewGroup
                    && ((ViewGroup) view).getChildCount() > 0) {
                apply((ViewGroup) view);
            }

        }

    }

}

在上面的代码中，我只在textView和EditText上应用字体，你也可以在其他视图元素上应用字体。你只需要把根视图组的id传递给上面的apply font方法。例如，你的布局是:

<RelativeLayout xmlns:android="http://schemas.android.com/apk/res/android"
    xmlns:tools="http://schemas.android.com/tools"
    android:layout_width="match_parent"
    android:layout_height="match_parent"
    android:orientation="vertical"
    android:id="@+id/mainParent"
    tools:context="${relativePackage}.${activityClass}" >

    <RelativeLayout
        android:id="@+id/mainContainer"
        android:layout_width="match_parent"
        android:layout_height="wrap_content"
        android:layout_above="@+id/homeFooter"
        android:layout_below="@+id/edit" >

        <ImageView
            android:id="@+id/PreviewImg"
            android:layout_width="match_parent"
            android:layout_height="match_parent"
            android:src="@drawable/abc_list_longpressed_holo"
            android:visibility="gone" />

        <RelativeLayout
            android:id="@+id/visibilityLayer"
            android:layout_width="match_parent"
            android:layout_height="fill_parent" >

            <ImageView
                android:id="@+id/UseCamera"
                android:layout_width="wrap_content"
                android:layout_height="wrap_content"
                android:layout_alignParentTop="true"
                android:layout_centerHorizontal="true"
                android:src="@drawable/camera" />

            <TextView
                android:id="@+id/tvOR"
                android:layout_width="wrap_content"
                android:layout_height="wrap_content"
                android:layout_below="@+id/UseCamera"
                android:layout_centerHorizontal="true"
                android:layout_marginTop="20dp"
                android:text="OR"
                android:textSize="30dp" />

            <TextView
                android:id="@+id/tvAND"
                android:layout_width="wrap_content"
                android:layout_height="wrap_content"
                android:layout_centerHorizontal="true"
                android:layout_marginTop="20dp"
                android:text="OR"
                android:textSize="30dp" />

</RelativeLayout>

在上面的布局中，根父id是“Main parent”，现在让我们应用字体

public class MainActivity extends BaseFragmentActivity {

    private EditText etName;
    private EditText etPassword;
    private TextView tvTitle;
    public static boolean isHome = false;

    @Override
    protected void onCreate(Bundle savedInstanceState) {
        super.onCreate(savedInstanceState);
        setContentView(R.layout.activity_main);

       Font font=Font.getInstance(getApplicationContext());
        FontHelper.applyFont(findViewById(R.id.mainParent),          getApplicationContext());
   }    
}

欢呼:)

我还想改进weston对API 21 Android 5.0的回答。

我的三星s5在使用默认字体时也遇到了同样的问题。(与其他字体的工作很好)

我设法使它工作通过设置字体(“sans”为例)在XML文件，为每个Textview或按钮

<TextView
android:layout_width="match_parent"
android:layout_height="39dp"
android:textColor="@color/abs__background_holo_light"
android:textSize="12sp"
android:gravity="bottom|center"
android:typeface="sans" />

在MyApplication类中:

public class MyApplication extends Application {
    @Override
    public void onCreate() {
    TypefaceUtil.overrideFont(getApplicationContext(), "SANS_SERIF",
    "fonts/my_font.ttf");
    }
}

希望能有所帮助。

我建议扩展TextView，并始终使用您的自定义TextView在您的XML布局或任何地方，你需要一个TextView。在你的自定义TextView，覆盖setTypeface

@Override
public void setTypeface(Typeface tf, int style) {
    //to handle bold, you could also handle italic or other styles here as well
    if (style == 1){
        tf = Typeface.createFromAsset(getContext().getApplicationContext().getAssets(), "MuseoSans700.otf");
    }else{
        tf = Typeface.createFromAsset(getContext().getApplicationContext().getAssets(), "MuseoSans500.otf");
    }
    super.setTypeface(tf, 0);
}

我写了一个类，将字体分配给当前视图层次结构中的视图，并基于当前字体属性(粗体，正常，如果你想，你可以添加其他样式):

public final class TypefaceAssigner {

public final Typeface DEFAULT;
public final Typeface DEFAULT_BOLD;

@Inject
public TypefaceAssigner(AssetManager assetManager) {
    DEFAULT = Typeface.createFromAsset(assetManager, "TradeGothicLTCom.ttf");
    DEFAULT_BOLD = Typeface.createFromAsset(assetManager, "TradeGothicLTCom-Bd2.ttf");
}

public void assignTypeface(View v) {
    if (v instanceof ViewGroup) {
        for (int i = 0; i < ((ViewGroup) v).getChildCount(); i++) {
            View view = ((ViewGroup) v).getChildAt(i);
            if (view instanceof ViewGroup) {
                setTypeface(view);
            } else {
                setTypeface(view);
            }
        }
    } else {
        setTypeface(v);
    }
}

private void setTypeface(View view) {
    if (view instanceof TextView) {
        TextView textView = (TextView) view;
        Typeface typeface = textView.getTypeface();
        if (typeface != null && typeface.isBold()) {
            textView.setTypeface(DEFAULT_BOLD);
        } else {
            textView.setTypeface(DEFAULT);
        }
    }
}
}

现在，在onViewCreated或onCreateView的所有片段中，在onCreate中的所有活动中，在getView或newView中的所有视图适配器中，只需调用:

typefaceAssigner.assignTypeface(view);

我发现书法库和coderwall的帖子的混合是我的最终结果。

Tom的解决方案很好，但只适用于TextView和EditText。

如果你想覆盖大部分的视图(RadioGroup, TextView，复选框…)，我创建了一个方法:

protected void changeChildrenFont(ViewGroup v, Typeface font){
    for(int i = 0; i < v.getChildCount(); i++){

        // For the ViewGroup, we'll have to use recursivity
        if(v.getChildAt(i) instanceof ViewGroup){
            changeChildrenFont((ViewGroup) v.getChildAt(i), font);
        }
        else{
            try {
                Object[] nullArgs = null;
                //Test wether setTypeface and getTypeface methods exists
                Method methodTypeFace = v.getChildAt(i).getClass().getMethod("setTypeface", new Class[] {Typeface.class, Integer.TYPE});
                //With getTypefaca we'll get back the style (Bold, Italic...) set in XML
                Method methodGetTypeFace = v.getChildAt(i).getClass().getMethod("getTypeface", new Class[] {});
                Typeface typeFace = ((Typeface)methodGetTypeFace.invoke(v.getChildAt(i), nullArgs));
                //Invoke the method and apply the new font with the defined style to the view if the method exists (textview,...)
                methodTypeFace.invoke(v.getChildAt(i), new Object[] {font, typeFace == null ? 0 : typeFace.getStyle()});
            }
            //Will catch the view with no such methods (listview...)
            catch (Exception e) {
                e.printStackTrace();
            }
        }
    }
}

该方法将返回视图集的XML样式(粗体，斜体…)，并在它们存在时应用它们。

对于ListView，我总是创建一个适配器，并在getView中设置字体。