如果你想要一种非阻塞的方式来周期性地执行你的函数，而不是阻塞无限循环，我会使用线程计时器。这样，您的代码可以继续运行并执行其他任务，并且仍然每n秒调用一次您的函数。我经常使用这种技术打印长时间、CPU/磁盘/网络密集型任务的进度信息。

下面是我在类似问题中发布的代码，带有start()和stop()控件:

from threading import Timer

class RepeatedTimer(object):
    def __init__(self, interval, function, *args, **kwargs):
        self._timer     = None
        self.interval   = interval
        self.function   = function
        self.args       = args
        self.kwargs     = kwargs
        self.is_running = False
        self.start()

    def _run(self):
        self.is_running = False
        self.start()
        self.function(*self.args, **self.kwargs)

    def start(self):
        if not self.is_running:
            self._timer = Timer(self.interval, self._run)
            self._timer.start()
            self.is_running = True

    def stop(self):
        self._timer.cancel()
        self.is_running = False

用法:

from time import sleep

def hello(name):
    print "Hello %s!" % name

print "starting..."
rt = RepeatedTimer(1, hello, "World") # it auto-starts, no need of rt.start()
try:
    sleep(5) # your long-running job goes here...
finally:
    rt.stop() # better in a try/finally block to make sure the program ends!

特点:

只有标准库，没有外部依赖 即使计时器已经启动/停止，也可以安全地多次调用Start()和stop() 要调用的函数可以有位置参数和命名参数 您可以随时更改间隔，它将在下次运行后生效。args、kwargs甚至function也一样!

如果您的程序还没有事件循环，请使用sched模块，它实现了一个通用的事件调度器。

import sched, time

def do_something(scheduler): 
    # schedule the next call first
    scheduler.enter(60, 1, do_something, (scheduler,))
    print("Doing stuff...")
    # then do your stuff

my_scheduler = sched.scheduler(time.time, time.sleep)
my_scheduler.enter(60, 1, do_something, (my_scheduler,))
my_scheduler.run()

如果您已经在使用事件循环库，如asyncio、trio、tkinter、PyQt5、gobject、kivy等，则只需使用现有事件循环库的方法来调度任务。

下面是MestreLion对代码的更新，它可以避免随着时间的推移而漂移。

这里的RepeatedTimer类按照OP的请求每隔“间隔”秒调用给定函数;调度并不取决于函数执行的时间。我喜欢这个解决方案，因为它没有外部库依赖关系;这是纯python。

import threading 
import time

class RepeatedTimer(object):
  def __init__(self, interval, function, *args, **kwargs):
    self._timer = None
    self.interval = interval
    self.function = function
    self.args = args
    self.kwargs = kwargs
    self.is_running = False
    self.next_call = time.time()
    self.start()

  def _run(self):
    self.is_running = False
    self.start()
    self.function(*self.args, **self.kwargs)

  def start(self):
    if not self.is_running:
      self.next_call += self.interval
      self._timer = threading.Timer(self.next_call - time.time(), self._run)
      self._timer.start()
      self.is_running = True

  def stop(self):
    self._timer.cancel()
    self.is_running = False

示例用法(摘自MestreLion的回答):

from time import sleep

def hello(name):
    print "Hello %s!" % name

print "starting..."
rt = RepeatedTimer(1, hello, "World") # it auto-starts, no need of rt.start()
try:
    sleep(5) # your long-running job goes here...
finally:
    rt.stop() # better in a try/finally block to make sure the program ends!

我用这个方法使每小时产生60个事件，其中大多数事件在整分钟后的相同秒数内发生:

import math
import time
import random

TICK = 60 # one minute tick size
TICK_TIMING = 59 # execute on 59th second of the tick
TICK_MINIMUM = 30 # minimum catch up tick size when lagging

def set_timing():

    now = time.time()
    elapsed = now - info['begin']
    minutes = math.floor(elapsed/TICK)
    tick_elapsed = now - info['completion_time']
    if (info['tick']+1) > minutes:
        wait = max(0,(TICK_TIMING-(time.time() % TICK)))
        print ('standard wait: %.2f' % wait)
        time.sleep(wait)
    elif tick_elapsed < TICK_MINIMUM:
        wait = TICK_MINIMUM-tick_elapsed
        print ('minimum wait: %.2f' % wait)
        time.sleep(wait)
    else:
        print ('skip set_timing(); no wait')
    drift = ((time.time() - info['begin']) - info['tick']*TICK -
        TICK_TIMING + info['begin']%TICK)
    print ('drift: %.6f' % drift)

info['tick'] = 0
info['begin'] = time.time()
info['completion_time'] = info['begin'] - TICK

while 1:

    set_timing()

    print('hello world')

    #random real world event
    time.sleep(random.random()*TICK_MINIMUM)

    info['tick'] += 1
    info['completion_time'] = time.time()

根据实际情况，你可能会得到长度的刻度:

60,60,62,58,60,60,120,30,30,60,60,60,60,60...etc.

但在60分钟结束时，你会有60个滴答;而且它们中的大多数都将出现在您喜欢的正确偏移时间。

在我的系统中，我得到了< 1/20秒的典型漂移，直到需要纠正。

该方法的优点是具有较好的时钟漂移分辨率;这可能会导致问题，如果你做的事情，比如每tick追加一个项目，你希望每小时追加60个项目。未能考虑漂移可能导致次要指标，如移动平均线，将数据考虑得过于深入过去，从而导致错误的输出。

简单地使用

import time

while True:
    print("this will run after every 30 sec")
    #Your code here
    time.sleep(30)

这里是另一个不使用任何额外库的解决方案。

def delay_until(condition_fn, interval_in_sec, timeout_in_sec):
    """Delay using a boolean callable function.

    `condition_fn` is invoked every `interval_in_sec` until `timeout_in_sec`.
    It can break early if condition is met.

    Args:
        condition_fn     - a callable boolean function
        interval_in_sec  - wait time between calling `condition_fn`
        timeout_in_sec   - maximum time to run

    Returns: None
    """
    start = last_call = time.time()
    while time.time() - start < timeout_in_sec:
        if (time.time() - last_call) > interval_in_sec:
            if condition_fn() is True:
                break
            last_call = time.time()