您正在向self添加所有已定义的约束。视图的宽度和高度限制应该添加到你的newView。

另外，据我所知，你想要设置恒定的宽度和高度100:100。 在这种情况下，您应该将代码更改为:

var constW = NSLayoutConstraint(item: newView, 
    attribute: .Width, 
    relatedBy: .Equal, 
    toItem: nil, 
    attribute: .NotAnAttribute, 
    multiplier: 1, 
    constant: 100)
newView.addConstraint(constW)

var constH = NSLayoutConstraint(item: newView, 
    attribute: .Height, 
    relatedBy: .Equal, 
    toItem: nil, 
    attribute: .NotAnAttribute, 
    multiplier: 1, 
    constant: 100)
newView.addConstraint(constH)

如果你想要填充你的超级视图，那么我建议快速的方法:

view.translatesAutoresizingMaskIntoConstraints = false
let attributes: [NSLayoutAttribute] = [.top, .bottom, .right, .left]
NSLayoutConstraint.activate(attributes.map {
    NSLayoutConstraint(item: view, attribute: $0, relatedBy: .equal, toItem: view.superview, attribute: $0, multiplier: 1, constant: 0)
})

否则，如果你需要非相等的约束检查NSLayoutAnchor作为iOS 9。使用NSLayoutConstraint直接读取通常要容易得多:

view.translatesAutoresizingMaskIntoConstraints = false
view.topAnchor.constraint(equalTo: view.superview!.topAnchor).isActive = true
view.bottomAnchor.constraint(equalTo: view.superview!.bottomAnchor).isActive = true
view.leadingAnchor.constraint(equalTo: view.superview!.leadingAnchor, constant: 10).isActive = true
view.trailingAnchor.constraint(equalTo: view.superview!.trailingAnchor, constant: 10).isActive = true

Swift 3更新

import UIKit

class ViewController: UIViewController {

let redView: UIView = {

    let view = UIView()
    view.translatesAutoresizingMaskIntoConstraints = false
    view.backgroundColor = .red
    return view
}()

override func viewDidLoad() {
    super.viewDidLoad()

    setupViews()
    setupAutoLayout()
}

func setupViews() {

    view.backgroundColor = .white
    view.addSubview(redView)
}

func setupAutoLayout() {

    // Available from iOS 9 commonly known as Anchoring System for AutoLayout...
    redView.leftAnchor.constraint(equalTo: view.leftAnchor, constant: 20).isActive = true
    redView.rightAnchor.constraint(equalTo: view.rightAnchor, constant: -20).isActive = true

    redView.centerYAnchor.constraint(equalTo: view.centerYAnchor).isActive = true
    redView.heightAnchor.constraint(equalToConstant: 300).isActive = true

    // You can also modified above last two lines as follows by commenting above & uncommenting below lines...
    // redView.topAnchor.constraint(equalTo: view.topAnchor, constant: 20).isActive = true
    // redView.bottomAnchor.constraint(equalTo: view.bottomAnchor).isActive = true
 }
}

约束的类型

 /*
// regular use
1.leftAnchor
2.rightAnchor
3.topAnchor
// intermediate use
4.widthAnchor
5.heightAnchor
6.bottomAnchor
7.centerXAnchor
8.centerYAnchor
// rare use
9.leadingAnchor
10.trailingAnchor
etc. (note: very project to project)
*/

这是一种以编程方式添加约束的方法

override func viewDidLoad() {
            super.viewDidLoad()


let myLabel = UILabel()
        myLabel.labelFrameUpdate(label: myLabel, text: "Welcome User", font: UIFont(name: "times new roman", size: 40)!, textColor: UIColor.red, textAlignment: .center, numberOfLines: 0, borderWidth: 2.0, BorderColor: UIColor.red.cgColor)
        self.view.addSubview(myLabel)


         let myLabelhorizontalConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.centerX, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.centerX, multiplier: 1, constant: 0)
        let myLabelverticalConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.centerY, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.centerY, multiplier: 1, constant: 0)
        let mylabelLeading = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.leading, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.leading, multiplier: 1, constant: 10)
        let mylabelTrailing = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.trailing, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.trailing, multiplier: 1, constant: -10)
        let myLabelheightConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.height, relatedBy: NSLayoutRelation.equal, toItem: nil, attribute: NSLayoutAttribute.notAnAttribute, multiplier: 1, constant: 50)
        NSLayoutConstraint.activate(\[myLabelhorizontalConstraint, myLabelverticalConstraint, myLabelheightConstraint,mylabelLeading,mylabelTrailing\])
}

extension UILabel
{
    func labelFrameUpdate(label:UILabel,text:String = "This is sample Label",font:UIFont = UIFont(name: "times new roman", size: 20)!,textColor:UIColor = UIColor.red,textAlignment:NSTextAlignment = .center,numberOfLines:Int = 0,borderWidth:CGFloat = 2.0,BorderColor:CGColor = UIColor.red.cgColor){
        label.translatesAutoresizingMaskIntoConstraints = false
        label.text = text
        label.font = font
        label.textColor = textColor
        label.textAlignment = textAlignment
        label.numberOfLines = numberOfLines
        label.layer.borderWidth = borderWidth
        label.layer.borderColor = UIColor.red.cgColor
    }
}

你计划在UIViewController的UIView中有一个宽度为100和高度为100的平方UIView吗?如果是这样，你可以尝试以下6种自动布局风格之一(Swift 5 / iOS 12.2):

---

1. 使用NSLayoutConstraint初始化器

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let horizontalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0)
    let verticalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0)
    let widthConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.width, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100)
    let heightConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.height, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100)
    view.addConstraints([horizontalConstraint, verticalConstraint, widthConstraint, heightConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let horizontalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0)
    let verticalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0)
    let widthConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.width, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100)
    let heightConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.height, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100)
    NSLayoutConstraint.activate([horizontalConstraint, verticalConstraint, widthConstraint, heightConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0).isActive = true
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0).isActive = true
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.width, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100).isActive = true
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.height, relatedBy: NSLayoutConstraint.Relation.equal, toItem: nil, attribute: NSLayoutConstraint.Attribute.notAnAttribute, multiplier: 1, constant: 100).isActive = true
}

---

2. 使用可视化格式语言

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let views = ["view": view!, "newView": newView]
    let horizontalConstraints = NSLayoutConstraint.constraints(withVisualFormat: "H:[view]-(<=0)-[newView(100)]", options: NSLayoutConstraint.FormatOptions.alignAllCenterY, metrics: nil, views: views)
    let verticalConstraints = NSLayoutConstraint.constraints(withVisualFormat: "V:[view]-(<=0)-[newView(100)]", options: NSLayoutConstraint.FormatOptions.alignAllCenterX, metrics: nil, views: views)
    view.addConstraints(horizontalConstraints)
    view.addConstraints(verticalConstraints)
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let views = ["view": view!, "newView": newView]
    let horizontalConstraints = NSLayoutConstraint.constraints(withVisualFormat: "H:[view]-(<=0)-[newView(100)]", options: NSLayoutConstraint.FormatOptions.alignAllCenterY, metrics: nil, views: views)
    let verticalConstraints = NSLayoutConstraint.constraints(withVisualFormat: "V:[view]-(<=0)-[newView(100)]", options: NSLayoutConstraint.FormatOptions.alignAllCenterX, metrics: nil, views: views)
    NSLayoutConstraint.activate(horizontalConstraints)
    NSLayoutConstraint.activate(verticalConstraints)
}

---

3.混合使用NSLayoutConstraint初始化器和可视格式语言

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let views = ["newView": newView]
    let widthConstraints = NSLayoutConstraint.constraints(withVisualFormat: "H:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    let heightConstraints = NSLayoutConstraint.constraints(withVisualFormat: "V:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    let horizontalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0)
    let verticalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0)
    view.addConstraints(widthConstraints)
    view.addConstraints(heightConstraints)
    view.addConstraints([horizontalConstraint, verticalConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let views = ["newView": newView]
    let widthConstraints = NSLayoutConstraint.constraints(withVisualFormat: "H:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    let heightConstraints = NSLayoutConstraint.constraints(withVisualFormat: "V:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    let horizontalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0)
    let verticalConstraint = NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0)
    NSLayoutConstraint.activate(widthConstraints)
    NSLayoutConstraint.activate(heightConstraints)
    NSLayoutConstraint.activate([horizontalConstraint, verticalConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = false
    let views = ["newView": newView]
    let widthConstraints = NSLayoutConstraint.constraints(withVisualFormat: "H:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    let heightConstraints = NSLayoutConstraint.constraints(withVisualFormat: "V:[newView(100)]", options: NSLayoutConstraint.FormatOptions(rawValue: 0), metrics: nil, views: views)
    NSLayoutConstraint.activate(widthConstraints)
    NSLayoutConstraint.activate(heightConstraints)
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerX, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerX, multiplier: 1, constant: 0).isActive = true
    NSLayoutConstraint(item: newView, attribute: NSLayoutConstraint.Attribute.centerY, relatedBy: NSLayoutConstraint.Relation.equal, toItem: view, attribute: NSLayoutConstraint.Attribute.centerY, multiplier: 1, constant: 0).isActive = true
}

---

4. 使用UIView。AutoresizingMask

注意:spring和Struts将在运行时转换为相应的自动布局约束。

override func viewDidLoad() {
    let newView = UIView(frame: CGRect(x: 0, y: 0, width: 100, height: 100))
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)

    newView.translatesAutoresizingMaskIntoConstraints = true
    newView.center = CGPoint(x: view.bounds.midX, y: view.bounds.midY)
    newView.autoresizingMask = [UIView.AutoresizingMask.flexibleLeftMargin, UIView.AutoresizingMask.flexibleRightMargin, UIView.AutoresizingMask.flexibleTopMargin, UIView.AutoresizingMask.flexibleBottomMargin]
}

---

5. 使用NSLayoutAnchor

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)
    
    newView.translatesAutoresizingMaskIntoConstraints = false
    let horizontalConstraint = newView.centerXAnchor.constraint(equalTo: view.centerXAnchor)
    let verticalConstraint = newView.centerYAnchor.constraint(equalTo: view.centerYAnchor)
    let widthConstraint = newView.widthAnchor.constraint(equalToConstant: 100)
    let heightConstraint = newView.heightAnchor.constraint(equalToConstant: 100)
    view.addConstraints([horizontalConstraint, verticalConstraint, widthConstraint, heightConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)
    
    newView.translatesAutoresizingMaskIntoConstraints = false
    let horizontalConstraint = newView.centerXAnchor.constraint(equalTo: view.centerXAnchor)
    let verticalConstraint = newView.centerYAnchor.constraint(equalTo: view.centerYAnchor)
    let widthConstraint = newView.widthAnchor.constraint(equalToConstant: 100)
    let heightConstraint = newView.heightAnchor.constraint(equalToConstant: 100)
    NSLayoutConstraint.activate([horizontalConstraint, verticalConstraint, widthConstraint, heightConstraint])
}

override func viewDidLoad() {
    let newView = UIView()
    newView.backgroundColor = UIColor.red
    view.addSubview(newView)
    
    newView.translatesAutoresizingMaskIntoConstraints = false
    newView.centerXAnchor.constraint(equalTo: view.centerXAnchor).isActive = true
    newView.centerYAnchor.constraint(equalTo: view.centerYAnchor).isActive = true
    newView.widthAnchor.constraint(equalToConstant: 100).isActive = true
    newView.heightAnchor.constraint(equalToConstant: 100).isActive = true
}

---

6. 使用intrinsicContentSize和NSLayoutAnchor

import UIKit

class CustomView: UIView {
    
    override var intrinsicContentSize: CGSize {
        return CGSize(width: 100, height: 100)
    }
    
}

class ViewController: UIViewController {
    
    override func viewDidLoad() {
        let newView = CustomView()
        newView.backgroundColor = UIColor.red
        view.addSubview(newView)
        
        newView.translatesAutoresizingMaskIntoConstraints = false
        let horizontalConstraint = newView.centerXAnchor.constraint(equalTo: view.centerXAnchor)
        let verticalConstraint = newView.centerYAnchor.constraint(equalTo: view.centerYAnchor)
        NSLayoutConstraint.activate([horizontalConstraint, verticalConstraint])
    }
    
}

---

结果:

想在Imanou Petit的回答中添加一些理论概念，这样人们就可以了解自动布局是如何工作的。

要理解自动布局，请将您的视图视为橡胶的对象，最初是收缩的。

要在屏幕上放置一个对象，我们需要4件强制性的事情:

物体的X坐标(水平位置)。 物体的Y坐标(垂直位置) 对象的宽度 物体的高度。

X坐标:有多种方式给视图X坐标。

如前向约束，后向约束，水平中心 等。

2 Y坐标:给视图Y坐标有多种方式:

如顶部约束，底部约束，垂直中心等。

有两种方法来限制一个视图的宽度:

a.添加固定宽度约束(将此约束视为固定宽度的铁棒，并与橡胶对象水平挂钩，使橡胶对象不会收缩或膨胀)

b.不要添加任何宽度约束，而是在视图的前端和前端添加x坐标约束，这两个约束将通过从前端和前端拉动橡胶对象来扩展/收缩。

对象的高度:类似于宽度，有两种方法来限制视图的高度:

a.添加固定高度约束(将此约束视为固定高度的铁棒，并与橡胶物体垂直挂钩，使橡胶物体不会收缩或膨胀)

b.不要添加任何高度约束，但在视图的顶部和底部两端添加x坐标约束，这两个约束将从两端、顶部和底部拉伸/推动橡胶对象。