这个问题，正如错误消息所暗示的，是你的NSAutoresizingMaskLayoutConstraints类型的约束与你的显式约束冲突，因为new_view。translatesAutoresizingMaskIntoConstraints设置为true。

这是在代码中创建的视图的默认设置。你可以像这样关闭它:

var new_view:UIView! = UIView(frame: CGRectMake(0, 0, 100, 100))
new_view.translatesAutoresizingMaskIntoConstraints = false

此外，宽度和高度的限制也很奇怪。如果你想让视图有一个恒定的宽度，这是正确的方法:

new_view.addConstraint(NSLayoutConstraint(
    item:new_view, attribute:NSLayoutAttribute.Width,
    relatedBy:NSLayoutRelation.Equal,
    toItem:nil, attribute:NSLayoutAttribute.NotAnAttribute,
    multiplier:0, constant:100))

(将100替换为您想要的宽度。)

如果你的部署目标是iOS 9.0或更高版本，你可以使用这个简短的代码:

new_view.widthAnchor.constraintEqualToConstant(100).active = true

不管怎样，对于这样的布局(固定大小，在父视图居中)，使用自动调整蒙版并让系统将蒙版转换为约束会更简单:

var new_view:UIView! = UIView(frame: CGRectMake(0, 0, 100, 100))
new_view.backgroundColor = UIColor.redColor();
view.addSubview(new_view);

// This is the default setting but be explicit anyway...
new_view.translatesAutoresizingMaskIntoConstraints = true

new_view.autoresizingMask = [ .FlexibleTopMargin, .FlexibleBottomMargin,
    .FlexibleLeftMargin, .FlexibleRightMargin ]

new_view.center = CGPointMake(view.bounds.midX, view.bounds.midY)

请注意，使用自动调整大小是完全合法的，即使你也使用自动布局。(UIKit仍然在内部的很多地方使用自动调整大小。)问题是很难对使用自动调整大小的视图应用额外的约束。

这是一种以编程方式添加约束的方法

override func viewDidLoad() {
            super.viewDidLoad()


let myLabel = UILabel()
        myLabel.labelFrameUpdate(label: myLabel, text: "Welcome User", font: UIFont(name: "times new roman", size: 40)!, textColor: UIColor.red, textAlignment: .center, numberOfLines: 0, borderWidth: 2.0, BorderColor: UIColor.red.cgColor)
        self.view.addSubview(myLabel)


         let myLabelhorizontalConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.centerX, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.centerX, multiplier: 1, constant: 0)
        let myLabelverticalConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.centerY, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.centerY, multiplier: 1, constant: 0)
        let mylabelLeading = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.leading, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.leading, multiplier: 1, constant: 10)
        let mylabelTrailing = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.trailing, relatedBy: NSLayoutRelation.equal, toItem: self.view, attribute: NSLayoutAttribute.trailing, multiplier: 1, constant: -10)
        let myLabelheightConstraint = NSLayoutConstraint(item: myLabel, attribute: NSLayoutAttribute.height, relatedBy: NSLayoutRelation.equal, toItem: nil, attribute: NSLayoutAttribute.notAnAttribute, multiplier: 1, constant: 50)
        NSLayoutConstraint.activate(\[myLabelhorizontalConstraint, myLabelverticalConstraint, myLabelheightConstraint,mylabelLeading,mylabelTrailing\])
}

extension UILabel
{
    func labelFrameUpdate(label:UILabel,text:String = "This is sample Label",font:UIFont = UIFont(name: "times new roman", size: 20)!,textColor:UIColor = UIColor.red,textAlignment:NSTextAlignment = .center,numberOfLines:Int = 0,borderWidth:CGFloat = 2.0,BorderColor:CGColor = UIColor.red.cgColor){
        label.translatesAutoresizingMaskIntoConstraints = false
        label.text = text
        label.font = font
        label.textColor = textColor
        label.textAlignment = textAlignment
        label.numberOfLines = numberOfLines
        label.layer.borderWidth = borderWidth
        label.layer.borderColor = UIColor.red.cgColor
    }
}

在xcode 7.3.1中略有不同。这是我想到的

   // creating the view
        let newView = UIView()
        newView.backgroundColor = UIColor.redColor()
        newView.translatesAutoresizingMaskIntoConstraints = false
        view.addSubview(newView)

        // creating the constraint 

        // attribute and relation cannot be set directyl you need to create a cariable of them
        let layout11 = NSLayoutAttribute.CenterX
        let layout21 = NSLayoutRelation.Equal
        let layout31 = NSLayoutAttribute.CenterY
        let layout41 = NSLayoutAttribute.Width
        let layout51 = NSLayoutAttribute.Height
        let layout61 = NSLayoutAttribute.NotAnAttribute

        // defining all the constraint
        let horizontalConstraint = NSLayoutConstraint(item: newView, attribute: layout11, relatedBy: layout21, toItem: view, attribute: layout11, multiplier: 1, constant: 0)
        let verticalConstraint = NSLayoutConstraint(item: newView, attribute: layout31, relatedBy: layout21, toItem: view, attribute: layout31, multiplier: 1, constant: 0)
        let widthConstraint = NSLayoutConstraint(item: newView, attribute: layout41, relatedBy: layout21, toItem: nil, attribute: layout61, multiplier: 1, constant: 100)
        let heightConstraint = NSLayoutConstraint(item: newView, attribute: layout51, relatedBy: layout21, toItem: nil, attribute: layout61, multiplier: 1, constant: 100)

        // adding all the constraint
        NSLayoutConstraint.activateConstraints([horizontalConstraint,verticalConstraint,widthConstraint,heightConstraint])

这个错误是由autoresizingmask自动创建的约束引起的，它们的创建是因为UIView属性translatesAutoresizingMaskIntoConstraints默认为true。

考虑使用BoxView来摆脱所有手工约束创建样板，并使您的代码简洁易读。用BoxView做布局是非常简单的:

boxView.items = [
   new_view.boxed.centerX().centerY().relativeWidth(1.0).relativeHeight(1.0)
]

您可以使用Snapkit以编程方式设置约束。

class ViewController: UIViewController {
    
    let rectView: UIView = UIView(frame: CGRect(x: 0, y: 0, width: 100, height: 100))
    
    override func viewDidLoad() {
        super.viewDidLoad()
        setupViews()
    }
    
    private func setupViews() {
        rectView.backgroundColor = .red
        view.addSubview(rectView)

        rectView.snp.makeConstraints {
          $0.center.equalToSuperview()
        }
    }
}

    var xCenterConstraint : NSLayoutConstraint!
    var yCenterConstraint: NSLayoutConstraint!

 xCenterConstraint = NSLayoutConstraint(item: self.view, attribute: .CenterX, relatedBy: .Equal, toItem: (Your view NAme), attribute: .CenterX, multiplier: 1, constant: 0)
            self.view.addConstraint(xCenterConstraint)

 yCenterConstraint = NSLayoutConstraint(item: self.view, attribute: .CenterY, relatedBy: .Equal, toItem: (Your view Name), attribute: .CenterY, multiplier: 1, constant: 0)
            self.view.addConstraint(yCenterConstraint)