在Xcode 6中，你可以在storyboard中这样做:

我做了这个简单的扩展，非常适合我:

extension UILabel {
    func setLineHeight(lineHeight: CGFloat) {
        let paragraphStyle = NSMutableParagraphStyle()
        paragraphStyle.lineSpacing = 1.0
        paragraphStyle.lineHeightMultiple = lineHeight
        paragraphStyle.alignment = self.textAlignment

        let attrString = NSMutableAttributedString()
        if (self.attributedText != nil) {
            attrString.append( self.attributedText!)
        } else {
            attrString.append( NSMutableAttributedString(string: self.text!))
            attrString.addAttribute(NSAttributedStringKey.font, value: self.font, range: NSMakeRange(0, attrString.length))
        }
        attrString.addAttribute(NSAttributedStringKey.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))
        self.attributedText = attrString
    }
}

复制到一个文件中，这样你就可以像这样使用它了

myLabel.setLineHeight(0.7)

我想在这个答案中加入一些新的东西，这样我就不会感觉那么糟糕了……以下是斯威夫特的回答:

import Cocoa

let paragraphStyle = NSMutableParagraphStyle()
paragraphStyle.lineSpacing = 40

let attrString = NSMutableAttributedString(string: "Swift Answer")
attrString.addAttribute(.paragraphStyle, value:paragraphStyle, range:NSMakeRange(0, attrString.length))

var tableViewCell = NSTableCellView()
tableViewCell.textField.attributedStringValue = attrString

简单的回答是:你不能。要改变文本行间的间距，你必须继承UILabel并滚动自己的drawTextInRect，或者创建多个标签。”

参见:设置UILabel行间距

这是一个非常老的答案，其他人已经添加了新的更好的方法来处理这个问题。请参阅下面提供的最新答案。

在UITextView或UILabel扩展中，添加这个函数:

我添加了一些代码来保持当前的带属性文本，如果您已经在视图中使用带属性字符串(而不是覆盖它们)。

func setLineHeight(_ lineHeight: CGFloat) {
    guard let text = self.text, let font = self.font else { return }

    let paragraphStyle = NSMutableParagraphStyle()
    paragraphStyle.lineSpacing = 1.0
    paragraphStyle.lineHeightMultiple = lineHeight
    paragraphStyle.alignment = self.textAlignment

    var attrString:NSMutableAttributedString
    if let attributed = self.attributedText {
        attrString = NSMutableAttributedString(attributedString: attributed)
    } else {
        attrString = NSMutableAttributedString(string: text)
        attrString.addAttribute(NSFontAttributeName, value: font, range: NSMakeRange(0, attrString.length))
    }
    attrString.addAttribute(NSParagraphStyleAttributeName, value:paragraphStyle, range:NSMakeRange(0, attrString.length))
    self.attributedText = attrString
}

这里提到的解决方案对我不起作用。我发现了一个稍微不同的方式来做它与iOS 6 NSAttributeString:

myLabel.numberOfLines = 0; 
NSString* string = @"String with line one. \n Line two. \n Line three.";
NSMutableParagraphStyle *style  = [[NSMutableParagraphStyle alloc] init];
style.minimumLineHeight = 30.f;
style.maximumLineHeight = 30.f;
NSDictionary *attributtes = @{NSParagraphStyleAttributeName : style,};
myLabel.attributedText = [[NSAttributedString alloc] initWithString:string
                                                         attributes:attributtes];   
[myLabel sizeToFit];

SWIFT 3有用的扩展设置行间的空间更容易:)

extension UILabel
{
    func setLineHeight(lineHeight: CGFloat)
    {
        let text = self.text
        if let text = text 
        {

            let attributeString = NSMutableAttributedString(string: text)
            let style = NSMutableParagraphStyle()

           style.lineSpacing = lineHeight
           attributeString.addAttribute(NSParagraphStyleAttributeName,
                                        value: style,
                                        range: NSMakeRange(0, text.characters.count))

           self.attributedText = attributeString
        }
    }
}