在较新的浏览器中，如Chrome 15, Firefox 10, Safari 5.1, IE 10，这是可能的。根据浏览器设置，旧版本的IE也可以通过ActiveX实现。

以下是如何做到这一点:

function requestFullScreen(element) {
    // Supports most browsers and their versions.
    var requestMethod = element.requestFullScreen || element.webkitRequestFullScreen || element.mozRequestFullScreen || element.msRequestFullScreen;

    if (requestMethod) { // Native full screen.
        requestMethod.call(element);
    } else if (typeof window.ActiveXObject !== "undefined") { // Older IE.
        var wscript = new ActiveXObject("WScript.Shell");
        if (wscript !== null) {
            wscript.SendKeys("{F11}");
        }
    }
}

var elem = document.body; // Make the body go full screen.
requestFullScreen(elem);

用户显然需要首先接受全屏请求，并且不可能在页面加载时自动触发此请求，它需要由用户触发(例如。一个按钮)

阅读更多信息:https://developer.mozilla.org/en/DOM/Using_full-screen_mode

这是JavaScript中最接近全屏的效果:

<script type="text/javascript">
    window.onload = maxWindow;

    function maxWindow() {
        window.moveTo(0, 0);

        if (document.all) {
            top.window.resizeTo(screen.availWidth, screen.availHeight);
        }

        else if (document.layers || document.getElementById) {
            if (top.window.outerHeight < screen.availHeight || top.window.outerWidth < screen.availWidth) {
                top.window.outerHeight = screen.availHeight;
                top.window.outerWidth = screen.availWidth;
            }
        }
    }
</script> 

这段代码还包括如何启用Internet Explorer 9的全屏，可能是更老的版本， 以及最新版本的谷歌Chrome。接受的答案也可以用于其他浏览器。

var el = document.documentElement
    , rfs = // for newer Webkit and Firefox
           el.requestFullscreen
        || el.webkitRequestFullScreen
        || el.mozRequestFullScreen
        || el.msRequestFullscreen
;
if(typeof rfs!="undefined" && rfs){
  rfs.call(el);
} else if(typeof window.ActiveXObject!="undefined"){
  // for Internet Explorer
  var wscript = new ActiveXObject("WScript.Shell");
  if (wscript!=null) {
     wscript.SendKeys("{F11}");
  }
}

来源:

Chrome全屏API(请注意，然而 requestFullscreen“只工作在”“[m]大多数UIEvents和鼠标事件，如点击和按下键等”，“所以它不能被恶意使用”) 如何使浏览器全屏使用F11键事件通过JavaScript

在Firefox 10中，你可以使用以下javascript使当前页面全屏(没有窗口chrome的真正全屏):

window.fullScreen = true;

幸运的是，对于毫无戒心的网络用户来说，这不能用javascript完成。你需要编写特定于浏览器的插件，如果它们还不存在的话，然后以某种方式让人们下载它们。你能得到的最接近的是一个最大化的窗口，没有工具或导航栏，但用户仍然能够看到url。

窗口.open(“http://www.wege.com”，“标题”，“类型”=fullWindow, fullscreen, scrollbars=yes);“>

这通常被认为是不好的做法，因为它从用户那里删除了很多浏览器功能。

简单的例子:http://www.longtailvideo.com/blog/26517/using-the-browsers-new-html5-fullscreen-capabilities/

<script type="text/javascript">
  function goFullscreen(id) {
    // Get the element that we want to take into fullscreen mode
    var element = document.getElementById(id);

    // These function will not exist in the browsers that don't support fullscreen mode yet, 
    // so we'll have to check to see if they're available before calling them.

    if (element.mozRequestFullScreen) {
      // This is how to go into fullscren mode in Firefox
      // Note the "moz" prefix, which is short for Mozilla.
      element.mozRequestFullScreen();
    } else if (element.webkitRequestFullScreen) {
      // This is how to go into fullscreen mode in Chrome and Safari
      // Both of those browsers are based on the Webkit project, hence the same prefix.
      element.webkitRequestFullScreen();
   }
   // Hooray, now we're in fullscreen mode!
  }
</script>

<img class="video_player" src="image.jpg" id="player"></img>
<button onclick="goFullscreen('player'); return false">Click Me To Go Fullscreen! (For real)</button>