我认为你应该首先定义你所有的路线，然后作为最后的路线添加

//The 404 Route (ALWAYS Keep this as the last route)
app.get('*', function(req, res){
  res.status(404).send('what???');
});

一个示例应用程序的工作:

app.js:

var express = require('express'),
    app = express.createServer();

app.use(express.static(__dirname + '/public'));

app.get('/', function(req, res){
  res.send('hello world');
});

//The 404 Route (ALWAYS Keep this as the last route)
app.get('*', function(req, res){
  res.send('what???', 404);
});

app.listen(3000, '127.0.0.1');

alfred@alfred-laptop:~/node/stackoverflow/6528876$ mkdir public
alfred@alfred-laptop:~/node/stackoverflow/6528876$ find .
alfred@alfred-laptop:~/node/stackoverflow/6528876$ echo "I don't find a function for that... Anyone knows?" > public/README.txt
alfred@alfred-laptop:~/node/stackoverflow/6528876$ cat public/README.txt 

.
./app.js
./public
./public/README.txt

alfred@alfred-laptop:~/node/stackoverflow/6528876$ curl http://localhost:3000/
hello world
alfred@alfred-laptop:~/node/stackoverflow/6528876$ curl http://localhost:3000/README.txt
I don't find a function for that... Anyone knows?

我认为你应该首先定义你所有的路线，然后作为最后的路线添加

//The 404 Route (ALWAYS Keep this as the last route)
app.get('*', function(req, res){
  res.status(404).send('what???');
});

一个示例应用程序的工作:

app.js:

var express = require('express'),
    app = express.createServer();

app.use(express.static(__dirname + '/public'));

app.get('/', function(req, res){
  res.send('hello world');
});

//The 404 Route (ALWAYS Keep this as the last route)
app.get('*', function(req, res){
  res.send('what???', 404);
});

app.listen(3000, '127.0.0.1');

alfred@alfred-laptop:~/node/stackoverflow/6528876$ mkdir public
alfred@alfred-laptop:~/node/stackoverflow/6528876$ find .
alfred@alfred-laptop:~/node/stackoverflow/6528876$ echo "I don't find a function for that... Anyone knows?" > public/README.txt
alfred@alfred-laptop:~/node/stackoverflow/6528876$ cat public/README.txt 

.
./app.js
./public
./public/README.txt

alfred@alfred-laptop:~/node/stackoverflow/6528876$ curl http://localhost:3000/
hello world
alfred@alfred-laptop:~/node/stackoverflow/6528876$ curl http://localhost:3000/README.txt
I don't find a function for that... Anyone knows?

https://github.com/robrighter/node-boilerplate/blob/master/templates/app/server.js

这就是node-boilerplate所做的。

app.get('*',function(req,res){
 res.redirect('/login');
});

Express-error-handler允许您为错误指定自定义模板、静态页面或错误处理程序。它还做了其他有用的错误处理，每个应用程序都应该实现，比如防止4xx错误DOS攻击，以及在不可恢复错误时优雅地关闭。以下是你如何做到你所要求的:

var errorHandler = require('express-error-handler'),
  handler = errorHandler({
    static: {
      '404': 'path/to/static/404.html'
    }
  });

// After all your routes...
// Pass a 404 into next(err)
app.use( errorHandler.httpError(404) );

// Handle all unhandled errors:
app.use( handler );

或者对于自定义处理程序:

handler = errorHandler({
  handlers: {
    '404': function err404() {
      // do some custom thing here...
    }
  }
}); 

或者对于自定义视图:

handler = errorHandler({
  views: {
    '404': '404.jade'
  }
});

你可以把一个中间件放在最后一个位置，它会抛出一个NotFound错误， 甚至直接渲染404页面:

app.use(function(req,res){
    res.status(404).render('404.jade');
});