这里的所有解决方案在某些情况下似乎都失败了，而且理解起来相当复杂。 特别是对于非拉丁语言，如阿拉伯语

这里有一个解码UTF-16的简短解决方案

//decodes utf-16 characters such as ARABIC, URDU,PASHTO text
function decodeBase64(s) {
    var percentEncodedStr = atob(s).split('').map(function (c) {
        return '%' + ('00' + c.charCodeAt(0).toString(16)).slice(-2);
    }).join('');
    return decodeURIComponent(percentEncodedStr);
}

这是一个缩小的填充窗口。Atob + window.btoa:

(function(){function t(t){this.message=t}var e="undefined"!=typeof exports?exports:this,r="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=";t.prototype=Error(),t.prototype.name="InvalidCharacterError",e.btoa||(e.btoa=function(e){for(var o,n,a=0,i=r,c="";e.charAt(0|a)||(i="=",a%1);c+=i.charAt(63&o>>8-8*(a%1))){if(n=e.charCodeAt(a+=.75),n>255)throw new t("'btoa' failed: The string to be encoded contains characters outside of the Latin1 range.");o=o<<8|n}return c}),e.atob||(e.atob=function(e){if(e=e.replace(/=+$/,""),1==e.length%4)throw new t("'atob' failed: The string to be decoded is not correctly encoded.");for(var o,n,a=0,i=0,c="";n=e.charAt(i++);~n&&(o=a%4?64*o+n:n,a++%4)?c+=String.fromCharCode(255&o>>(6&-2*a)):0)n=r.indexOf(n);return c})})();

(function (root, factory) {
    if (typeof define === 'function' && define.amd) {
        // AMD. Register as an anonymous module.
        define([], function() {factory(root);});
    } else factory(root);
// node.js has always supported base64 conversions, while browsers that support
// web workers support base64 too, but you may never know.
})(typeof exports !== "undefined" ? exports : this, function(root) {
    if (root.atob) {
        // Some browsers' implementation of atob doesn't support whitespaces
        // in the encoded string (notably, IE). This wraps the native atob
        // in a function that strips the whitespaces.
        // The original function can be retrieved in atob.original
        try {
            root.atob(" ");
        } catch(e) {
            root.atob = (function(atob) {
                var func = function(string) {
                    return atob(String(string).replace(/[\t\n\f\r ]+/g, ""));
                };
                func.original = atob;
                return func;
            })(root.atob);
        }
        return;
    }

        // base64 character set, plus padding character (=)
    var b64 = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=",
        // Regular expression to check formal correctness of base64 encoded strings
        b64re = /^(?:[A-Za-z\d+\/]{4})*?(?:[A-Za-z\d+\/]{2}(?:==)?|[A-Za-z\d+\/]{3}=?)?$/;

    root.btoa = function(string) {
        string = String(string);
        var bitmap, a, b, c,
            result = "", i = 0,
            rest = string.length % 3; // To determine the final padding

        for (; i < string.length;) {
            if ((a = string.charCodeAt(i++)) > 255
                    || (b = string.charCodeAt(i++)) > 255
                    || (c = string.charCodeAt(i++)) > 255)
                throw new TypeError("Failed to execute 'btoa' on 'Window': The string to be encoded contains characters outside of the Latin1 range.");

            bitmap = (a << 16) | (b << 8) | c;
            result += b64.charAt(bitmap >> 18 & 63) + b64.charAt(bitmap >> 12 & 63)
                    + b64.charAt(bitmap >> 6 & 63) + b64.charAt(bitmap & 63);
        }

        // If there's need of padding, replace the last 'A's with equal signs
        return rest ? result.slice(0, rest - 3) + "===".substring(rest) : result;
    };

    root.atob = function(string) {
        // atob can work with strings with whitespaces, even inside the encoded part,
        // but only \t, \n, \f, \r and ' ', which can be stripped.
        string = String(string).replace(/[\t\n\f\r ]+/g, "");
        if (!b64re.test(string))
            throw new TypeError("Failed to execute 'atob' on 'Window': The string to be decoded is not correctly encoded.");

        // Adding the padding if missing, for semplicity
        string += "==".slice(2 - (string.length & 3));
        var bitmap, result = "", r1, r2, i = 0;
        for (; i < string.length;) {
            bitmap = b64.indexOf(string.charAt(i++)) << 18 | b64.indexOf(string.charAt(i++)) << 12
                    | (r1 = b64.indexOf(string.charAt(i++))) << 6 | (r2 = b64.indexOf(string.charAt(i++)));

            result += r1 === 64 ? String.fromCharCode(bitmap >> 16 & 255)
                    : r2 === 64 ? String.fromCharCode(bitmap >> 16 & 255, bitmap >> 8 & 255)
                    : String.fromCharCode(bitmap >> 16 & 255, bitmap >> 8 & 255, bitmap & 255);
        }
        return result;
    };
});

完整版https://github.com/MaxArt2501/base64-js/blob/master/base64.js

对于我的项目，我仍然需要支持IE7和工作大输入编码。

根据Joe Dyndale提出的代码和Marius在评论中提出的建议，可以通过使用数组而不是字符串构造结果来提高IE7的性能。

下面是encode的例子:

var encode = function (input) {
    var output = [], chr1, chr2, chr3, enc1, enc2, enc3, enc4, i = 0;

    input = _utf8_encode(input);

    while (i < input.length) {

        chr1 = input.charCodeAt(i++);
        chr2 = input.charCodeAt(i++);
        chr3 = input.charCodeAt(i++);

        enc1 = chr1 >> 2;
        enc2 = ((chr1 & 3) << 4) | (chr2 >> 4);
        enc3 = ((chr2 & 15) << 2) | (chr3 >> 6);
        enc4 = chr3 & 63;

        if (isNaN(chr2)) {
            enc3 = enc4 = 64;
        } else if (isNaN(chr3)) {
            enc4 = 64;
        }

        output.push(_keyStr.charAt(enc1));
        output.push(_keyStr.charAt(enc2));
        output.push(_keyStr.charAt(enc3));
        output.push(_keyStr.charAt(enc4));

    }

    return output.join("");
};

您可以在浏览器中使用btoa()/atob()，但需要一些改进，如https://base64tool.com/uncaught-domexception-btoa-on-window/和https://developer.mozilla.org/en-US/docs/Web/API/WindowOrWorkerGlobalScope/btoa所述的UTF字符串支持!

虽然还有一些工作要做，但如果你想要一个高性能的本地解决方案，可以使用一些HTML5函数。

如果你可以把你的数据放到一个Blob中，那么你可以使用FileReader.readAsDataURL()函数来获得一个data:// URL，并砍掉它的前面来获得Base64数据。

你可能必须做进一步的处理，但urldecode数据，因为我不确定是否+字符转义或不为数据:// URL，但这应该是相当微不足道的。

Sunny的代码很棒，只是因为引用了“this”而在Internet Explorer 7中崩溃了。通过将这些引用替换为"Base64"来修复:

var Base64 = {
    // private property
    _keyStr : "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=",

    // public method for encoding
    encode : function (input) {
        var output = "";
        var chr1, chr2, chr3, enc1, enc2, enc3, enc4;
        var i = 0;

        input = Base64._utf8_encode(input);

        while (i < input.length) {

            chr1 = input.charCodeAt(i++);
            chr2 = input.charCodeAt(i++);
            chr3 = input.charCodeAt(i++);

            enc1 = chr1 >> 2;
            enc2 = ((chr1 & 3) << 4) | (chr2 >> 4);
            enc3 = ((chr2 & 15) << 2) | (chr3 >> 6);
            enc4 = chr3 & 63;

            if (isNaN(chr2)) {
                enc3 = enc4 = 64;
            } else if (isNaN(chr3)) {
                enc4 = 64;
            }

            output = output +
            Base64._keyStr.charAt(enc1) + Base64._keyStr.charAt(enc2) +
            Base64._keyStr.charAt(enc3) + Base64._keyStr.charAt(enc4);
        }

        return output;
    },

    // public method for decoding
    decode : function (input) {
        var output = "";
        var chr1, chr2, chr3;
        var enc1, enc2, enc3, enc4;
        var i = 0;

        input = input.replace(/[^A-Za-z0-9\+\/\=]/g, "");

        while (i < input.length) {

            enc1 = Base64._keyStr.indexOf(input.charAt(i++));
            enc2 = Base64._keyStr.indexOf(input.charAt(i++));
            enc3 = Base64._keyStr.indexOf(input.charAt(i++));
            enc4 = Base64._keyStr.indexOf(input.charAt(i++));

            chr1 = (enc1 << 2) | (enc2 >> 4);
            chr2 = ((enc2 & 15) << 4) | (enc3 >> 2);
            chr3 = ((enc3 & 3) << 6) | enc4;

            output = output + String.fromCharCode(chr1);

            if (enc3 != 64) {
                output = output + String.fromCharCode(chr2);
            }
            if (enc4 != 64) {
                output = output + String.fromCharCode(chr3);
            }
        }

        output = Base64._utf8_decode(output);

        return output;
    },

    // private method for UTF-8 encoding
    _utf8_encode : function (string) {
        string = string.replace(/\r\n/g,"\n");
        var utftext = "";

        for (var n = 0; n < string.length; n++) {

            var c = string.charCodeAt(n);

            if (c < 128) {
                utftext += String.fromCharCode(c);
            }
            else if((c > 127) && (c < 2048)) {
                utftext += String.fromCharCode((c >> 6) | 192);
                utftext += String.fromCharCode((c & 63) | 128);
            }
            else {
                utftext += String.fromCharCode((c >> 12) | 224);
                utftext += String.fromCharCode(((c >> 6) & 63) | 128);
                utftext += String.fromCharCode((c & 63) | 128);
            }
        }
        return utftext;
    },

    // private method for UTF-8 decoding
    _utf8_decode : function (utftext) {
        var string = "";
        var i = 0;
        var c = c1 = c2 = 0;

        while ( i < utftext.length ) {

            c = utftext.charCodeAt(i);

            if (c < 128) {
                string += String.fromCharCode(c);
                i++;
            }
            else if((c > 191) && (c < 224)) {
                c2 = utftext.charCodeAt(i+1);
                string += String.fromCharCode(((c & 31) << 6) | (c2 & 63));
                i += 2;
            }
            else {
                c2 = utftext.charCodeAt(i+1);
                c3 = utftext.charCodeAt(i+2);
                string += String.fromCharCode(((c & 15) << 12) | ((c2 & 63) << 6) | (c3 & 63));
                i += 3;
            }
        }
        return string;
    }
}