我有问题与接受的答案，所以我更新了它，这是为我工作:

.h

@interface MaxSpacingCollectionViewFlowLayout : UICollectionViewFlowLayout
@property (nonatomic,assign) CGFloat maxCellSpacing;
@end

.m

@implementation MaxSpacingCollectionViewFlowLayout

- (NSArray *) layoutAttributesForElementsInRect:(CGRect)rect {
    NSArray *attributes = [super layoutAttributesForElementsInRect:rect];

    if (attributes.count <= 0) return attributes;

    CGFloat firstCellOriginX = ((UICollectionViewLayoutAttributes *)attributes[0]).frame.origin.x;

    for(int i = 1; i < attributes.count; i++) {
        UICollectionViewLayoutAttributes *currentLayoutAttributes = attributes[i];
        if (currentLayoutAttributes.frame.origin.x == firstCellOriginX) { // The first cell of a new row
            continue;
        }

        UICollectionViewLayoutAttributes *prevLayoutAttributes = attributes[i - 1];
        CGFloat prevOriginMaxX = CGRectGetMaxX(prevLayoutAttributes.frame);
        if ((currentLayoutAttributes.frame.origin.x - prevOriginMaxX) > self.maxCellSpacing) {
            CGRect frame = currentLayoutAttributes.frame;
            frame.origin.x = prevOriginMaxX + self.maxCellSpacing;
            currentLayoutAttributes.frame = frame;
        }
    }
    return attributes;
}

@end

Swift 5 UIKit编程

 //Create UICollectionView
lazy var collectionView: UICollectionView = {
    
    let layout = UICollectionViewFlowLayout()
    layout.scrollDirection = .horizontal
    
    //CollectionCellView width autoSize
    layout.estimatedItemSize = UICollectionViewFlowLayout.automaticSize
    
    let collectionView = UICollectionView(frame: .zero, collectionViewLayout: layout)
    collectionView.translatesAutoresizingMaskIntoConstraints = false
    
    collectionView.register(CustomCollectionViewCell.self, forCellWithReuseIdentifier: cellId)
    collectionView.backgroundColor = .clear
    collectionView.delegate = self
    collectionView.dataSource = self
    collectionView.alwaysBounceHorizontal = true

//Add Spacing in each cell
    layout.minimumInteritemSpacing = 15
    layout.minimumLineSpacing = 15
    
    return collectionView
}()

Swift 3版本

简单地创建一个UICollectionViewFlowLayout子类并粘贴这个方法。

override func layoutAttributesForElements(in rect: CGRect) -> [UICollectionViewLayoutAttributes]? {
        guard let answer = super.layoutAttributesForElements(in: rect) else { return nil }

        for i in 1..<answer.count {
            let currentAttributes = answer[i]
            let previousAttributes = answer[i - 1]

            let maximumSpacing: CGFloat = 8
            let origin = previousAttributes.frame.maxX

            if (origin + maximumSpacing + currentAttributes.frame.size.width < self.collectionViewContentSize.width && currentAttributes.frame.origin.x > previousAttributes.frame.origin.x) {
                var frame = currentAttributes.frame
                frame.origin.x = origin + maximumSpacing
                currentAttributes.frame = frame
            }
        }

        return answer
}

支持第一个问题。我试图在UICollectionView上获得5px的间距，但这并不奏效，以及UIEdgeInsetsMake(0,0,0,0)…

在UITableView中，我可以通过直接指定一行中的x,y坐标来做到这一点。

这是我的UICollectionView代码:

#pragma mark collection view cell layout / size
- (CGSize)collectionView:(UICollectionView*)collectionView layout:(UICollectionViewLayout *)collectionViewLayout sizeForItemAtIndexPath:(NSIndexPath *)indexPath {
    return [self getCellSize:indexPath];  // will be w120xh100 or w190x100
    // if the width is higher, only one image will be shown in a line
}

#pragma mark collection view cell paddings
- (UIEdgeInsets)collectionView:(UICollectionView*)collectionView layout:(UICollectionViewLayout *)collectionViewLayout insetForSectionAtIndex:(NSInteger)section {
    return UIEdgeInsetsMake(0, 0, 0, 0); // top, left, bottom, right
}

- (CGFloat)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout minimumInteritemSpacingForSectionAtIndex:(NSInteger)section {

    return 5.0;
}

更新:用下面的代码解决了我的问题。

ViewController。m

#import "ViewController.h"
#import "MagazineCell.h" // created just the default class. 

static NSString * const cellID = @"cellID";

@interface ViewController ()

@end

@implementation ViewController

#pragma mark - Collection view
-(NSInteger)numberOfSectionsInCollectionView:(UICollectionView *)collectionView
{
    return 1;
}
-(NSInteger)collectionView:(UICollectionView *)collectionView numberOfItemsInSection:(NSInteger)section
{
    return 30;
}

-(UICollectionViewCell *)collectionView:(UICollectionView *)collectionView cellForItemAtIndexPath:(NSIndexPath *)indexPath
{
    MagazineCell *mCell = (MagazineCell *)[collectionView dequeueReusableCellWithReuseIdentifier:cellID forIndexPath:indexPath];

    mCell.backgroundColor = [UIColor lightGrayColor];

    return mCell;
}

#pragma mark Collection view layout things
// Layout: Set cell size
- (CGSize)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout sizeForItemAtIndexPath:(NSIndexPath *)indexPath {

    NSLog(@"SETTING SIZE FOR ITEM AT INDEX %d", indexPath.row);
    CGSize mElementSize = CGSizeMake(104, 104);
    return mElementSize;
}
- (CGFloat)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout minimumInteritemSpacingForSectionAtIndex:(NSInteger)section {
    return 2.0;
}

- (CGFloat)collectionView:(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout minimumLineSpacingForSectionAtIndex:(NSInteger)section {
    return 2.0;
}

// Layout: Set Edges
- (UIEdgeInsets)collectionView:
(UICollectionView *)collectionView layout:(UICollectionViewLayout*)collectionViewLayout insetForSectionAtIndex:(NSInteger)section {
   // return UIEdgeInsetsMake(0,8,0,8);  // top, left, bottom, right
    return UIEdgeInsetsMake(0,0,0,0);  // top, left, bottom, right
}

@end

记住，它是最小行间距，而不是最小项间距或单元格间距。因为你的collectionView的滚动方向是水平的。

如果是垂直的，则需要为单元格之间的水平空间设置单元格空间或项间空间，为单元格之间的垂直空间设置行间距。

objective - c版本

- (CGFloat)collectionView:(UICollectionView *)collectionView
                       layout:(UICollectionViewLayout*)collectionViewLayout
    minimumLineSpacingForSectionAtIndex:(NSInteger)section
    {
        return 20;
    }

斯威夫特版本:

func collectionView(_ collectionView: UICollectionView, layout collectionViewLayout: UICollectionViewLayout, minimumLineSpacingForSectionAt section: Int) -> CGFloat {
    return 20
}

试试这个方法:

- (UIEdgeInsets)collectionView:(UICollectionView *)collectionView
                    layout:(UICollectionViewLayout*)collectionViewLayout
    insetForSectionAtIndex:(NSInteger)section {

    UIEdgeInsets insets = UIEdgeInsetsMake(?, ?, ?, ?);

    return insets;
}