在iOS 5.0+中使用Appearance API:

[[UISegmentedControl appearance] setTitleTextAttributes:[NSDictionary dictionaryWithObjectsAndKeys:[UIFont fontWithName:@"STHeitiSC-Medium" size:13.0], UITextAttributeFont, nil] forState:UIControlStateNormal];

链接: http://developer.apple.com/library/ios/#documentation/UIKit/Reference/UIAppearance_Protocol/Reference/Reference.html#//apple_ref/doc/uid/TP40010906

http://www.raywenderlich.com/4344/user-interface-customization-in-ios-5

丹尼尔指给我正确的路。我是这样用的-

float scaleFactor = 0.8f;

UISegmentedControl *segmentedControl = [[UISegmentedControl alloc]
initWithFrame:CGRectMake(10, 70, 300/scaleFactor,35)];

[segmentedControl insertSegmentWithTitle:@"..." atIndex:0 animated:NO];
[segmentedControl insertSegmentWithTitle:@"..." atIndex:1 animated:NO];
[segmentedControl insertSegmentWithTitle:@"..." atIndex:2 animated:NO];

segmentedControl.transform = CGAffineTransformMakeScale(scaleFactor, 1);
CGPoint segmentedControlCenter = segmentedControl.center;
segmentedControlCenter.x = self.center.x;
segmentedControl.center = segmentedControlCenter;

以下是Swift版本的公认答案:

斯威夫特3:

let font = UIFont.systemFont(ofSize: 16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font],
                                        for: .normal)

斯威夫特2.2:

let font = UIFont.systemFontOfSize(16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font], 
    forState: UIControlState.Normal)

在swift 5中，

let font = UIFont.systemFont(ofSize: 16)
UISegmentedControl.appearance().setTitleTextAttributes([NSAttributedString.Key.font: font], for: .normal)

 UISegmentedControl.appearance().setTitleTextAttributes(NSDictionary(objects: [UIFont.systemFont(ofSize: 16.0)],
                                                                        forKeys: [kCTFontAttributeName as! NSCopying]) as? [AnyHashable : Any],
                                                           for: UIControlState.normal)

另一种选择是对控件应用转换。然而，它将缩小一切，包括控制边界。

segmentedControl.transform = CGAffineTransformMakeScale(.6f, .6f);