以下是Swift版本的公认答案:

斯威夫特3:

let font = UIFont.systemFont(ofSize: 16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font],
                                        for: .normal)

斯威夫特2.2:

let font = UIFont.systemFontOfSize(16)
segmentedControl.setTitleTextAttributes([NSFontAttributeName: font], 
    forState: UIControlState.Normal)

这里我已经更新了iOS8

[[UISegmentedControl appearance] setTitleTextAttributes:[NSDictionary dictionaryWithObjectsAndKeys:[UIFont fontWithName:@"STHeitiSC-Medium" size:13.0], NSFontAttributeName, nil] forState:UIControlStateNormal];

2021年的正确答案。语法改变了。

12岁的答案(甚至是对它的编辑)是坏的。

它只是:

let _font = UIFont.systemFont(ofSize: 10)
UISegmentedControl.appearance()
 .setTitleTextAttributes([NSAttributedString.Key.font: _font], for: .normal)

你很可能会想要正确地改变高度，而你在它:

import UIKit

class SmallerSegmentedControl: UISegmentedControl {

    override init(frame: CGRect) {
        super.init(frame: frame)
        common()
    }

    required init?(coder aDecoder: NSCoder) {
        super.init(coder: aDecoder)
        common()
    }

    func common() {
        let _font = UIFont.systemFont(ofSize: 10)
        UISegmentedControl.appearance()
         .setTitleTextAttributes([NSAttributedString.Key.font: _font], for: .normal)
    }

    override var intrinsicContentSize:CGSize {
        var s = super.intrinsicContentSize
        s.height = 24
        return s
    }

}

XCode 8.1, Swift 3

import UIKit
class ViewController: UIViewController {
    override func viewDidLoad() {
        super.viewDidLoad()
        UISegmentedControl.appearance().setTitleTextAttributes(NSDictionary(objects: [UIFont.systemFont(ofSize: 24.0)], 
        forKeys: [NSFontAttributeName as NSCopying]) as? [AnyHashable : Any], 
        for: UIControlState.normal)
    }
}

只需要改变数值(ofSize: 24.0)

在iOS 5.0+中使用Appearance API:

[[UISegmentedControl appearance] setTitleTextAttributes:[NSDictionary dictionaryWithObjectsAndKeys:[UIFont fontWithName:@"STHeitiSC-Medium" size:13.0], UITextAttributeFont, nil] forState:UIControlStateNormal];

链接: http://developer.apple.com/library/ios/#documentation/UIKit/Reference/UIAppearance_Protocol/Reference/Reference.html#//apple_ref/doc/uid/TP40010906

http://www.raywenderlich.com/4344/user-interface-customization-in-ios-5

 UISegmentedControl.appearance().setTitleTextAttributes(NSDictionary(objects: [UIFont.systemFont(ofSize: 16.0)],
                                                                        forKeys: [kCTFontAttributeName as! NSCopying]) as? [AnyHashable : Any],
                                                           for: UIControlState.normal)