我知道这个问题已经有很长一段时间了，但我找到了一个简单的解决方法，并且认为有人可以使用它(对不起，英语不好)。是这样的:

CSS

.main, .sidebar {
    float: none;
    padding: 20px;
    vertical-align: top;
}
.container {
    display: table;
}
.main {
    width: 400px;
    background-color: LightSlateGrey;
    display: table-cell;
}
.sidebar {
    width: 200px;
    display: table-cell;
    background-color: Tomato;
}

HTML

<div class="container clearfix">
    <div class="sidebar">
        simple text here
    </div>
    <div class="main">
        Lorem ipsum dolor sit amet, consectetur adipiscing elit. Etiam congue, tortor in mattis mattis, arcu erat pharetra orci, at vestibulum lorem ante a felis. Integer sit amet est ac elit vulputate lobortis. Vestibulum in ipsum nulla. Aenean erat elit, lacinia sit amet adipiscing quis, aliquet at erat. Vivamus massa sem, cursus vel semper non, dictum vitae mi. Donec sed bibendum ante.
    </div>
</div>

简单的例子。注意，您可以将其转换为响应性。

你可以把display: flex到div#主，align-self: stretch到div#导航。

<div id="header"></div>

<div id="main">
  <div id="navigation"></div>
  <div id="content"></div>
</div>

<div id="footer"></div>

// CSS file
#main {
  display: flex;
}

#navigation {
  align-self: stretch;
}    

#main {
    overflow: hidden;
}
#navigation, #content {
    margin-bottom: -1000px;
    padding-bottom: 1000px;
}

下面的代码提供了设置滚动div的最小高度的能力，并通过使用flex使其具有其父div的100%高度。

CSS:

.main {
  display: flex;
  flex-direction: column;
}

.scroll {
  overflow: auto;
  flex: 1 0 50px;
}

HTML:

<div class="main">
  <div class="scroll">
    Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.
    Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.
    Lorem Ipsum is simply dummy text of the printing and typesetting industry. Lorem Ipsum has been the industry's standard dummy text ever since the 1500s, when an unknown printer took a galley of type and scrambled it to make a type specimen book. It has survived not only five centuries, but also the leap into electronic typesetting, remaining essentially unchanged. It was popularised in the 1960s with the release of Letraset sheets containing Lorem Ipsum passages, and more recently with desktop publishing software like Aldus PageMaker including versions of Lorem Ipsum.
  </div>
</div>

我可能有点晚了，但我找到了一个周围的工作，可能是一个hack。 首先给父层一个弯曲和100vh的高度

就像这样:

.parent {
   display: flex;
   justify-content: center;
   align-items: center;
   height: 100vh;/* Can be less depends on the container, basically this forces the element to expand */
}

将display: grid添加到父节点