一种有效但不太有效的方法是在文档中添加带有新内容的规则，并用类引用它。根据需要，类可能需要为内容中的每个值提供唯一的id。

$("<style type='text/css'>span.id-after:after{content:bar;}</style>").appendTo($("head"));
$('span').addClass('id-after');

我在CSS中使用:root中定义的变量来修改:after(同样适用于:before)伪元素，特别是在下面使用JavaScript/jQuery生成随机颜色的演示中，更改由. slide -middle-out:hover:after定义的样式锚的背景颜色值和另一个锚(#reference)的内容值:

HTML

<a href="#" id="changeColor" class="sliding-middle-out" title="Generate a random color">Change link color</a>
<span id="log"></span>
<h6>
  <a href="https://stackoverflow.com/a/52360188/2149425" id="reference" class="sliding-middle-out" target="_blank" title="Stack Overflow topic">Reference</a>
</h6>
<script type="text/javascript" src="https://cdnjs.cloudflare.com/ajax/libs/jquery/3.3.1/jquery.min.js"></script>
<script type="text/javascript" src="https://cdn.rawgit.com/davidmerfield/randomColor/master/randomColor.js"></script>

CSS

:root {
    --anchorsFg: #0DAFA4;
}
a, a:visited, a:focus, a:active {
    text-decoration: none;
    color: var(--anchorsFg);
    outline: 0;
    font-style: italic;

    -webkit-transition: color 250ms ease-in-out;
    -moz-transition: color 250ms ease-in-out;
    -ms-transition: color 250ms ease-in-out;
    -o-transition: color 250ms ease-in-out;
    transition: color 250ms ease-in-out;
}
.sliding-middle-out {
    display: inline-block;
    position: relative;
    padding-bottom: 1px;
}
.sliding-middle-out:after {
    content: '';
    display: block;
    margin: auto;
    height: 1px;
    width: 0px;
    background-color: transparent;

    -webkit-transition: width 250ms ease-in-out, background-color 250ms ease-in-out;
    -moz-transition: width 250ms ease-in-out, background-color 250ms ease-in-out;
    -ms-transition: width 250ms ease-in-out, background-color 250ms ease-in-out;
    -o-transition: width 250ms ease-in-out, background-color 250ms ease-in-out;
    transition: width 250ms ease-in-out, background-color 250ms ease-in-out;
}
.sliding-middle-out:hover:after {
    width: 100%;
    background-color: var(--anchorsFg);
    outline: 0;
}
#reference {
  margin-top: 20px;
}
.sliding-middle-out:before {
  content: attr(data-content);
  display: attr(data-display);
}

JS / jQuery

var anchorsFg = randomColor();
$( ".sliding-middle-out" ).hover(function(){
    $( ":root" ).css({"--anchorsFg" : anchorsFg});
});

$( "#reference" ).hover(
 function(){
    $(this).attr("data-content", "Hello World!").attr("data-display", "block").html("");
 },
 function(){
    $(this).attr("data-content", "Reference").attr("data-display", "inline").html("");
 }
);

只需要在之前或之后设置伪样式来继承，然后用javascript设置父样式。

例如，我想改变:before的颜色样式，然后我设置:

.my-style::before{
color: inherit;
}

然后我用javascript改变了.my-style元素的颜色样式:

document.querySelector(".my-style").style.color = red;

工作完成了，超级简单

你也可以将内容传递给带有data属性的伪元素，然后使用jQuery来操作它:

在HTML中:

<span>foo</span>

jQuery:

$('span').hover(function(){
    $(this).attr('data-content','bar');
});

在CSS中:

span:after {
    content: attr(data-content) ' any other text you may want';
}

如果你想阻止“其他文本”出现，你可以将此与seucolega的解决方案结合起来，如下所示:

在HTML中:

<span>foo</span>

jQuery:

$('span').hover(function(){
    $(this).addClass('change').attr('data-content','bar');
});

在CSS中:

span.change:after {
    content: attr(data-content) ' any other text you may want';
}

您可以创建一个伪属性，也可以使用一个现有的属性，并在伪元素的样式表中继承它。

var switched = false; // Enable color switching setInterval(function () { var color = switched ? 'red' : 'darkred'; var element = document.getElementById('arrow'); element.style.backgroundColor = color; // Managing pseudo-element's css // using inheritance. element.style.borderLeftColor = color; switched = !switched; }, 1000); .arrow { /* SET FICTIONAL PROPERTY */ border-left-color:red; background-color:red; width:1em; height:1em; display:inline-block; position:relative; } .arrow:after { border-top:1em solid transparent; border-right:1em solid transparent; border-bottom:1em solid transparent; border-left:1em solid transparent; /* INHERIT PROPERTY */ border-left-color:inherit; content:""; width:0; height:0; position:absolute; left:100%; top:-50%; } <span id="arrow" class="arrow"></span>

似乎它对“content”属性不起作用:(

根据克里斯蒂安的建议，你还可以这样做:

$('head').append("<style>.span::after{ content:'bar' }</style>");