我的问题是在Windows 2003服务器，当调用AuthenticateAsClient。上面的解决方案(例如绕过ServicePointManager.ServerCertificateValidationCallback)不起作用。

原来这是Windows 2003中的一个bug，并且有一个热修复:

"使用加密API的应用程序无法在Windows Server 2003中验证X.509证书"

https://support.microsoft.com/en-us/kb/938397

安装此修复程序解决了我的问题。

它解决了我的问题

smtpClient.Credentials = new NetworkCredential(sendMail.UserName, sendMail.Password);
smtpClient.EnableSsl = false;//sendMail.EnableSSL;

//参考//问题只出现在使用上述行设置false SSl，解决在SMTP设置中输入用户名和密码时出错的问题。

由于ssl，从outlook发送时得到相同的错误。尝试设置EnableSSL = false解决了这个问题。

例子:

var smtp = new SmtpClient
                {
                    Host = "smtp.gmail.com",                   
                    Port = 587,
                    EnableSsl = false,
                    DeliveryMethod = SmtpDeliveryMethod.Network,
                    UseDefaultCredentials = false,                   
                    Credentials = new NetworkCredential("xxx@gmail.com", "xxxxx")
                };

当我试图通过代理服务器(Usergate)使用SmtpClient发送电子邮件时，我有同样的错误。

验证包含服务器地址的证书，该证书不等于代理服务器地址，因此出现错误。 我的解决方案:当检查证书时发生错误，接收证书，导出并检查。

public static bool RemoteServerCertificateValidationCallback(Object sender, X509Certificate certificate, X509Chain chain, SslPolicyErrors sslPolicyErrors)
    {
        if (sslPolicyErrors == SslPolicyErrors.None)
            return true;

        // if got an cert auth error
        if (sslPolicyErrors != SslPolicyErrors.RemoteCertificateNameMismatch) return false;
        const string sertFileName = "smpthost.cer";

        // check if cert file exists
        if (File.Exists(sertFileName))
        {
            var actualCertificate = X509Certificate.CreateFromCertFile(sertFileName);
            return certificate.Equals(actualCertificate);
        }

        // export and check if cert not exists
        using (var file = File.Create(sertFileName))
        {
            var cert = certificate.Export(X509ContentType.Cert);
            file.Write(cert, 0, cert.Length);
        }
        var createdCertificate = X509Certificate.CreateFromCertFile(sertFileName);
        return certificate.Equals(createdCertificate);
    }

我的电子邮件发件人类的完整代码:

public class EmailSender
{
    private readonly SmtpClient _smtpServer;
    private readonly MailAddress _fromAddress;

    public EmailSender()
    {
        ServicePointManager.ServerCertificateValidationCallback = RemoteServerCertificateValidationCallback;
        _smtpServer = new SmtpClient();
    }

    public EmailSender(string smtpHost, int smtpPort, bool enableSsl, string userName, string password, string fromEmail, string fromName) : this()
    {
        _smtpServer.Host = smtpHost;
        _smtpServer.Port = smtpPort;
        _smtpServer.UseDefaultCredentials = false;
        _smtpServer.EnableSsl = enableSsl;
        _smtpServer.Credentials = new NetworkCredential(userName, password);

        _fromAddress = new MailAddress(fromEmail, fromName);
    }

    public bool Send(string address, string mailSubject, string htmlMessageBody,
        string fileName = null)
    {
        return Send(new List<MailAddress> { new MailAddress(address) }, mailSubject, htmlMessageBody, fileName);
    }

    public bool Send(List<MailAddress> addressList, string mailSubject, string htmlMessageBody,
        string fileName = null)
    {
        var mailMessage = new MailMessage();
        try
        {
            if (_fromAddress != null)
                mailMessage.From = _fromAddress;

            foreach (var addr in addressList)
                mailMessage.To.Add(addr);

            mailMessage.SubjectEncoding = Encoding.UTF8;
            mailMessage.Subject = mailSubject;

            mailMessage.Body = htmlMessageBody;
            mailMessage.BodyEncoding = Encoding.UTF8;
            mailMessage.IsBodyHtml = true;

            if ((fileName != null) && (System.IO.File.Exists(fileName)))
            {
                var attach = new Attachment(fileName, MediaTypeNames.Application.Octet);
                attach.ContentDisposition.CreationDate = System.IO.File.GetCreationTime(fileName);
                attach.ContentDisposition.ModificationDate = System.IO.File.GetLastWriteTime(fileName);
                attach.ContentDisposition.ReadDate = System.IO.File.GetLastAccessTime(fileName);
                mailMessage.Attachments.Add(attach);
            }
            _smtpServer.Send(mailMessage);
        }
        catch (Exception e)
        {
            // TODO lor error
            return false;
        }
        return true;
    }

    public static bool RemoteServerCertificateValidationCallback(Object sender, X509Certificate certificate, X509Chain chain, SslPolicyErrors sslPolicyErrors)
{
    if (sslPolicyErrors == SslPolicyErrors.None)
        return true;

    // if got an cert auth error
    if (sslPolicyErrors != SslPolicyErrors.RemoteCertificateNameMismatch) return false;
    const string sertFileName = "smpthost.cer";

    // check if cert file exists
    if (File.Exists(sertFileName))
    {
        var actualCertificate = X509Certificate.CreateFromCertFile(sertFileName);
        return certificate.Equals(actualCertificate);
    }

    // export and check if cert not exists
    using (var file = File.Create(sertFileName))
    {
        var cert = certificate.Export(X509ContentType.Cert);
        file.Write(cert, 0, cert.Length);
    }
    var createdCertificate = X509Certificate.CreateFromCertFile(sertFileName);
    return certificate.Equals(createdCertificate);
}

}

还没有人指出明显的，如果你想安全地调试SSL问题，那么总是使用这种方法:

#if DEBUG
    ServicePointManager.ServerCertificateValidationCallback += (sender, cert, chain, sslPolicyErrors) => true;
#endif

即使您不小心提交了代码，它也不会在发布模式下编译。

这里的链接解决了我的问题。

http://brainof-dave.blogspot.com.au/2008/08/remote-certificate-is-invalid-according.html

我去到web服务的url(在有问题的服务器上)，点击IE中的小安全图标，弹出证书。然后，我单击Details选项卡，单击Copy To File按钮，这允许我将证书导出为.cer文件。在本地获得证书后，我就可以使用下面的说明将其导入服务器上的证书存储区。

开始一个新的MMC。 文件——>添加/删除管理单元… 单击Add…… 选择“证书”，单击“添加”。 选中“计算机帐户”单选按钮。单击Next。

在下一个屏幕中选择客户端计算机。单击Finish。 单击Close。 单击OK。 现在将证书安装到受信任的根证书颁发机构证书存储区中。这将允许所有用户信任该证书。