做这个设置。菜单->视图->显示符号->取消勾选显示行结束

在替换对话框中，您要将搜索模式设置为“扩展”。正常或正则表达式模式不工作。

然后只需要找到"\r\n"(对于unix文件只需要\n，对于mac格式文件只需要\r)，然后将替换值设置为你想要的任何值。

我在NP v6.9中完全无法做到这一点。 我发现用微软的Word (2K)软件就足够简单了。

打开文档，点击编辑->replace。

然后在搜索框的底部，点击“更多”，然后找到“特别”按钮，他们有一些东西给你。对于Dos样式，我使用“段落”样式。这是一双橱窗里的cr。

做这个设置。菜单->视图->显示符号->取消勾选显示行结束

CRLF图像

不含CRLF的图像

[\r\n]+也可以

2012年3月26日更新，notepad++ 6.0发布日期:

天哪，它现在真的有用了!!

原答案2008 (notepad++ 4.x) - 2009-2010-2011 (notepad++ 5.x)

实际上不，它似乎不能与regexp一起工作…

但是如果你有notepad++ 5。X，你可以使用“扩展”搜索模式，寻找\r\n。它能找到你所有的CRLF。

(我意识到这是与其他答案相同的答案，但同样，“扩展模式”仅适用于notepad++ 4.9, 5。X及更多)

自2009年4月以来，在notepad++站点上有一篇关于这个主题的wiki文章: 如何替换行尾，从而改变行布局。 (georgiecasey在他/她的回答中提到)

一些相关摘要包括以下搜索过程:

Simple search (Ctrl+F), Search Mode = Normal You can select an EOL in the editing window. Just move the cursor to the end of the line, and type Shift+Right Arrow. or, to select EOL with the mouse, start just at the line end and drag to the start of the next line; dragging to the right of the EOL won't work. You can manually copy the EOL and paste it into the field for Unix files (LF-only). Simple search (Ctrl+F), Search Mode = Extended The "Extended" option shows \n and \r as characters that could be matched. As with the Normal search mode, Notepad++ is looking for the exact character. Searching for \r in a UNIX-format file will not find anything, but searching for \n will. Similarly, a Macintosh-format file will contain \r but not \n. Simple search (Ctrl+F), Search Mode = Regular expression Regular expressions use the characters ^ and $ to anchor the match string to the beginning or end of the line. For instance, searching for return;$ will find occurrences of "return;" that occur with no subsequent text on that same line. The anchor characters work identically in all file formats. The '.' dot metacharacter does not match line endings. [Tested in Notepad++ 5.8.5]: a regular expression search with an explicit \r or \n does not work (contrary to the Scintilla documentation). Neither does a search on an explicit (pasted) LF, or on the (invisible) EOL characters placed in the field when an EOL is selected. Advanced search (Ctrl+R) without regexp Ctrl+M will insert something that matches newlines. They will be replaced by the replace string. I recommend this method as the most reliable, unless you really need to use regex. As an example, to remove every second newline in a double spaced file, enter Ctrl+M twice in the search string box, and once in the replace string box. Advanced search (Ctrl+R) with Regexp. Neither Ctrl+M, $ nor \r\n are matched.

同一维基还提到了十六进制编辑器的替代方案:

Type the new string at the beginning of the document. Then select to view the document in Hex mode. Select one of the new lines and hit Ctrl+H. While you have the Replace dialog box up, select on the background the new replacement string and Ctrl+C copy it to paste it in the Replace with text input. Then Replace or Replace All as you wish. Note: the character selected for new line usually appears as 0a. It may have a different value if the file is in Windows Format. In that case you can always go to Edit -> EOL Conversion -> Convert to Unix Format, and after the replacement switch it back and Edit -> EOL Conversion -> Convert to Windows Format.