我发现了一个有效的解决方案，证明内容也可以居中/空间均匀/等等…(如果你知道单行中的条目数):

HTML:

<section class="container">
    <div class="flex-item"></div>
    <div class="flex-item"></div>
    <div class="flex-item"></div>
    <div class="flex-item"></div>
    <div class="flex-item"></div>

    <p aria-hidden="true"></p>
    <p aria-hidden="true"></p>
    <p aria-hidden="true"></p>
  </section>

<p>标签的数量(它可以是任何其他标签)是每行中的项目数量减1。对于不同的屏幕尺寸，您可以使用媒体查询操作它。

CSS:

.container {
  display: flex;
  flex-wrap: wrap;
  justify-content: center;
  gap: 20px;
}

.flex-item {
  width: 300px;
  height: 300px;
  background: #21BA45;
}

.container > p {
  width: 300px;
  height: 300px;
}

可以使用“flex-start”手动添加页边距。它需要一些数学技巧，但绝对容易做到，并且很容易与CSS预处理器(如LESS)一起使用。

请看这个LESS mixin的例子:

.flexboxGridMixin(@columnNumber,@spacingPercent) {
  @contentPercent: 100% - @spacingPercent;
  @sideMargin: @spacingPercent/(@columnNumber*2);
  display: flex;
  flex-direction: row;
  flex-wrap: wrap;
  justify-content: flex-start;
  > * {
    box-sizing: border-box;
    width: @contentPercent/@columnNumber;
    margin-left: @sideMargin;
    margin-right: @sideMargin;
  }
}

然后它可以很容易地用来显示一个响应式网格布局:

ul {
  list-style: none;
  padding: 0;
  @spacing: 10%;
  @media only screen and (max-width: 499px) { .flexboxGridMixin(1,@spacing); }
  @media only screen and (min-width: 500px) { .flexboxGridMixin(2,@spacing); }
  @media only screen and (min-width: 700px) { .flexboxGridMixin(3,@spacing); }
  @media only screen and (min-width: 900px) { .flexboxGridMixin(4,@spacing); }
  @media only screen and (min-width: 1100px) { .flexboxGridMixin(5,@spacing); }
}

li {
  background: pink;
  height: 100px;
  margin-top: 20px;
}

这里有一个例子

http://codepen.io/anon/pen/YyLqVB?editors=110

你还可以这样做:

.exposegrid:last-child {
  margin-right: auto;
}

这很老套，但对我来说很管用。我试图达到一致的间距/边距。

.grid {
  width: 1024px;
  display: flex;
  flex-flow: row wrap;
  padding: 32px;
  background-color: #ddd;  

  &:after {
    content: "";
    flex: auto;
    margin-left:-1%;
  }

  .item {
    flex: 1 0 24.25%;
    max-width: 24.25%;
    margin-bottom: 10px;
    text-align: center;
    background-color: #bbb;

    &:nth-child(4n+2),
    &:nth-child(4n+3),
    &:nth-child(4n+4) {
      margin-left: 1%;
    }

    &:nth-child(4n+1):nth-last-child(-n+4),
      &:nth-child(4n+1):nth-last-child(-n+4) ~ .item {
        margin-bottom: 0;
    }    

  }
}

http://codepen.io/rustydev/pen/f7c8920e0beb0ba9a904da7ebd9970ae/

这个问题用CSS网格解决了，

这个解决方案只适用于你有固定数量的列，即没有。要显示在单行中的元素

->使用网格但不指定行数，随着元素数量的增加，它包装成列并动态添加行，我在这个例子中指定了三列

->你不需要给你的子/细胞任何位置，因为它会使它修复，这是我们不想要的。

.grid-class{
  display: grid;
  grid-template-columns: repeat(3, 1fr);
  column-gap: 80px;
}

这里有一些解决方案，人们建议编写精确的布局css类，使用伪元素伪造最后一项，使用非flexbox方法等。

一个大问题是邻居之间的间隙(大小写对齐的按钮包装到多行)。在这种情况下，你不希望物品相互接触，就需要有空隙。我只是想添加一个适当的解决方案，尊重差距，并适用于任何数量的项目。它也是基于假的最后一个元素的想法，但更普遍。有关详细信息，请参阅代码片段注释。

html { font-size: 1px; } .container { font-size: 16rem; display: flex; flex-wrap: wrap; justify-content: space-between; } .item { background-color: orange; border-radius: 10rem; box-sizing: border-box; color: white; margin-bottom: 10rem; padding: 15rem 10rem; text-align: center; } <!-- Our setup from design (example) used later in calculations: container-width: 100%; (can be any) max-per-row = 4; total = 6; desired-hor-gap = 10rem; (equal to vert. gap) If you go dynamic (drawing html according to the coming data either in a backend template or in a frontend template), you have to calculate and then set exact properties inline. <i> (or any real html element) is needed to set inline styles to arrange the last row properly. "2" in <i> calc function - is 6 % 4 since calc doesn't allow for "%" operator. But in real life you will calculate these numbers in JS or some backend template anyway. Formulas written in elements' calc functions. Seem to be self-descriptive, but the idea is to set for the last fake item the remainder width + hypothetical gaps. --> <div class="container"> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <div style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4);" class="item">do stuff</div> <i style="flex: 0 1 calc((100% - (4 - 1) * 10rem) / 4 * (4 - 2) + ( 4 - 2 - 1) * 10rem);"></i> </div>