我在这里找到了另一个问题的最佳答案。它只使用python内置库，不需要您输入本地时区(在我的情况下是一个要求)

import time
import calendar

local_time = time.strptime("2018-12-13T09:32:00.000", "%Y-%m-%dT%H:%M:%S.%f")
local_seconds = time.mktime(local_time)
utc_time = time.gmtime(local_seconds)

我在这里重新发布答案，因为这个问题在谷歌中弹出，而不是根据搜索关键字链接的问题。

首先，将字符串解析为简单的datetime对象。这是datetime的一个实例。没有附加时区信息的日期时间。请参阅其文档。

使用pytz模块，该模块提供了时区+ UTC的完整列表。找出本地时区是什么，从它构造一个timezone对象，并操作它并将其附加到naive datetime。

最后，使用datetime.astimezone()方法将datetime转换为UTC。

源代码，使用本地时区“America/Los_Angeles”，用于字符串“2001-2-3 10:11:12”:

from datetime import datetime   
import pytz

local = pytz.timezone("America/Los_Angeles")
naive = datetime.strptime("2001-2-3 10:11:12", "%Y-%m-%d %H:%M:%S")
local_dt = local.localize(naive, is_dst=None)
utc_dt = local_dt.astimezone(pytz.utc)

从那里，你可以使用strftime()方法来格式化UTC日期时间:

utc_dt.strftime("%Y-%m-%d %H:%M:%S")

怎么样——

time.strftime("%Y-%m-%dT%H:%M:%SZ", time.gmtime(seconds))

如果seconds为None，则将本地时间转换为UTC时间，否则将传入的时间转换为UTC时间。

下面是一些常见的Python时间转换的总结。

有些方法以秒为单位，用(s)标记。可以使用显式公式，如ts = (d - epoch) / unit代替(感谢jfs)。

struct_time (UTC) → POSIX (s):calendar.timegm(struct_time) Naïve datetime (local) → POSIX (s):calendar.timegm(stz.localize(dt, is_dst=None).utctimetuple())(exception during DST transitions, see comment from jfs) Naïve datetime (UTC) → POSIX (s):calendar.timegm(dt.utctimetuple()) Aware datetime → POSIX (s):calendar.timegm(dt.utctimetuple()) POSIX → struct_time (UTC, s):time.gmtime(t)(see comment from jfs) Naïve datetime (local) → struct_time (UTC, s):stz.localize(dt, is_dst=None).utctimetuple()(exception during DST transitions, see comment from jfs) Naïve datetime (UTC) → struct_time (UTC, s):dt.utctimetuple() Aware datetime → struct_time (UTC, s):dt.utctimetuple() POSIX → Naïve datetime (local):datetime.fromtimestamp(t, None)(may fail in certain conditions, see comment from jfs below) struct_time (UTC) → Naïve datetime (local, s):datetime.datetime(struct_time[:6], tzinfo=UTC).astimezone(tz).replace(tzinfo=None)(can't represent leap seconds, see comment from jfs) Naïve datetime (UTC) → Naïve datetime (local):dt.replace(tzinfo=UTC).astimezone(tz).replace(tzinfo=None) Aware datetime → Naïve datetime (local):dt.astimezone(tz).replace(tzinfo=None) POSIX → Naïve datetime (UTC):datetime.utcfromtimestamp(t) struct_time (UTC) → Naïve datetime (UTC, s):datetime.datetime(*struct_time[:6])(can't represent leap seconds, see comment from jfs) Naïve datetime (local) → Naïve datetime (UTC):stz.localize(dt, is_dst=None).astimezone(UTC).replace(tzinfo=None)(exception during DST transitions, see comment from jfs) Aware datetime → Naïve datetime (UTC):dt.astimezone(UTC).replace(tzinfo=None) POSIX → Aware datetime:datetime.fromtimestamp(t, tz)(may fail for non-pytz timezones) struct_time (UTC) → Aware datetime (s):datetime.datetime(struct_time[:6], tzinfo=UTC).astimezone(tz)(can't represent leap seconds, see comment from jfs) Naïve datetime (local) → Aware datetime:stz.localize(dt, is_dst=None)(exception during DST transitions, see comment from jfs) Naïve datetime (UTC) → Aware datetime:dt.replace(tzinfo=UTC)

来源:taaviburns.ca

我在dateutil(在SO网站上被广泛推荐用于其他相关问题)方面运气不错:

from datetime import *
from dateutil import *
from dateutil.tz import *

# METHOD 1: Hardcode zones:
utc_zone = tz.gettz('UTC')
local_zone = tz.gettz('America/Chicago')
# METHOD 2: Auto-detect zones:
utc_zone = tz.tzutc()
local_zone = tz.tzlocal()

# Convert time string to datetime
local_time = datetime.strptime("2008-09-17 14:02:00", '%Y-%m-%d %H:%M:%S')

# Tell the datetime object that it's in local time zone since 
# datetime objects are 'naive' by default
local_time = local_time.replace(tzinfo=local_zone)
# Convert time to UTC
utc_time = local_time.astimezone(utc_zone)
# Generate UTC time string
utc_string = utc_time.strftime('%Y-%m-%d %H:%M:%S')

(代码是从这个答案派生的，将UTC日期时间字符串转换为本地日期时间)

使用http://crsmithdev.com/arrow/

arrowObj = arrow.Arrow.strptime('2017-02-20 10:00:00', '%Y-%m-%d %H:%M:%S' , 'US/Eastern')

arrowObj.to('UTC') or arrowObj.to('local') 

这个库让生活变得简单:)