这是为我工作(更新的VS 2013，见2010年的修订历史，VS 2015见这个:https://stackoverflow.com/a/32744234/218971):

Right-click your Web Application Project ▶ Properties ▶ Web, then configure the Servers section as follows: Select IIS Express ▼ from the drop down Project Url: http://localhost Override application root URL: http://dev.example.com Click Create Virtual Directory (if you get an error here you may need to disable IIS 5/6/7/8, change IIS's Default Site to anything but port :80, make sure Skype isn't using port 80, etc.) Optionally: Set the Start URL to http://dev.example.com Open %USERPROFILE%\My Documents\IISExpress\config\applicationhost.config (Windows XP, Vista, and 7) and edit the site definition in the <sites> config block to be along the lines of the following: <site name="DevExample" id="997005936"> <application path="/" applicationPool="Clr2IntegratedAppPool"> <virtualDirectory path="/" physicalPath="C:\path\to\application\root" /> </application> <bindings> <binding protocol="http" bindingInformation=":80:dev.example.com" /> </bindings> <applicationDefaults applicationPool="Clr2IntegratedAppPool" /> </site> If running MVC: make sure the applicationPool is set to one of the "Integrated" options (like "Clr2IntegratedAppPool"). Open your hosts file and add the line 127.0.0.1 dev.example.com. ► Start your application!

评论中有一些很棒的建议:

您可能需要以管理员身份运行Visual Studio。 如果你想让其他开发人员看到你的IIS，运行netsh http add urlacl url=http://dev.example.com:80/ user=everyone 如果您希望站点为所有主机解析，请设置bindingInformation="*:80:"。 使用任何端口，80只是方便。要解析所有主机，您需要以管理员身份运行Visual Studio

以防万一有人需要…

我的要求是:

启用SSL 自定义的域 运行在(默认)端口:443

在IISExpress中设置这个URL: http://my.customdomain.com

为了设置这个，我使用了以下设置:

项目网址:http://localhost:57400

起始URL: http://my.customdomain.com

/ .vs / {solution-name} / config / applicationhost。配置设置:

<site ...>
    <application>
        ...
    </application>
    <bindings>
        <binding protocol="http" bindingInformation="*:57400:" />
        <binding protocol="https" bindingInformation="*:443:my.customdomain.com" />
    </bindings>
</site>

无效的主机名表明您在IIS Express配置文件中配置的实际站点(很可能)未运行。IIS Express没有IIS那样的流程模型。

要运行站点，需要显式启动(通过从webmatrix打开并访问，或者通过命令行调用iisexpress.exe(从它的安装目录)，并使用/site参数。

通常，允许使用完全限定的DNS名称进行本地访问的步骤如下 让我们使用DNS名称dev.example.com的示例

edit %windows%\system32\drivers\etc\hosts file to map dev.example.com to 127.0.0.1 (admin privilege required). If you control DNS server (like in Nick's case) then the DNS entry is sufficient as this step is not needed. If you access internet through proxy, make sure the dev.example.com will not be forwared to proxy (you have to put in on the exception list in your browser (for IE it would be Tools/Internet Options/Connections/Lan Settings, then go to Proxy Server/Advanced and put dev.example.com on the exeption list. Configure IIS Express binding for your site (eg:Site1) to include dev.example.com. Administrative privilege will be needed to use the binding. Alternatively, a one-time URL reservation can be made with http.sys using netsh http add urlacl url=http://dev.example.com:<port>/ user=<user_name> start iisexpress /site:Site1 or open Site1 in WebMatrix

这是为我工作(更新的VS 2013，见2010年的修订历史，VS 2015见这个:https://stackoverflow.com/a/32744234/218971):

Right-click your Web Application Project ▶ Properties ▶ Web, then configure the Servers section as follows: Select IIS Express ▼ from the drop down Project Url: http://localhost Override application root URL: http://dev.example.com Click Create Virtual Directory (if you get an error here you may need to disable IIS 5/6/7/8, change IIS's Default Site to anything but port :80, make sure Skype isn't using port 80, etc.) Optionally: Set the Start URL to http://dev.example.com Open %USERPROFILE%\My Documents\IISExpress\config\applicationhost.config (Windows XP, Vista, and 7) and edit the site definition in the <sites> config block to be along the lines of the following: <site name="DevExample" id="997005936"> <application path="/" applicationPool="Clr2IntegratedAppPool"> <virtualDirectory path="/" physicalPath="C:\path\to\application\root" /> </application> <bindings> <binding protocol="http" bindingInformation=":80:dev.example.com" /> </bindings> <applicationDefaults applicationPool="Clr2IntegratedAppPool" /> </site> If running MVC: make sure the applicationPool is set to one of the "Integrated" options (like "Clr2IntegratedAppPool"). Open your hosts file and add the line 127.0.0.1 dev.example.com. ► Start your application!

评论中有一些很棒的建议:

您可能需要以管理员身份运行Visual Studio。 如果你想让其他开发人员看到你的IIS，运行netsh http add urlacl url=http://dev.example.com:80/ user=everyone 如果您希望站点为所有主机解析，请设置bindingInformation="*:80:"。 使用任何端口，80只是方便。要解析所有主机，您需要以管理员身份运行Visual Studio

大卫的解决办法很好。但是我发现页面中的<script>警报(document.domain);</script>仍然警告“localhost”，因为项目Url仍然是localhost，即使它已经被http://dev.example.com覆盖。我遇到的另一个问题是，它提醒我端口80已经在使用，即使我已经禁用Skype使用80端口号，由大卫默多克推荐。所以我想出了另一个更简单的解决方案:

Run Notepad as administrator, and open the C:\Windows\System32\drivers\etc\hosts, add 127.0.0.1 mydomain, and save the file; Open the web project with Visual Studio 2013 (Note: must also run as administrator), right-click the project -> Properties -> Web, (lets suppose the Project Url under the "IIS Express" option is http://localhost:33333/), then change it from http://localhost:33333/ to http://mydomain:333333/ Note: After this change, you should neither click the "Create Virtual Directory" button on the right of the Project Url box nor click the Save button of the Visual Studio as they won't be succeeded. You can save your settings after next step 3. Open %USERPROFILE%\My Documents\IISExpress\config\applicationhost.config, search for "33333:localhost", then update it to "33333:mydomain" and save the file. Save your setting as mentioned in step 2. Right click a web page in your visual studio, and click "View in Browser". Now the page will be opened under http://mydomain:333333/, and <script>alert(document.domain);</script> in the page will alert "mydomain".

注意:上面列出的端口号假设为33333。您需要将其更改为您的visual studio设置的端口号。

Post编辑:今天我尝试了另一个域名，得到以下错误:无法启动IIS Express Web服务器。注册URL失败…访问被拒绝。(0 x80070005)。我通过右键单击Windows任务栏右下角的IIS Express图标退出IIS Express，然后以管理员身份重新启动我的visual studio，问题就解决了。

我试了以上所有的方法，都没用。解决这个问题的方法是在hosts文件中添加IPv6绑定。在@David murdoch回答的第五步中，添加两行而不是一行，即:

127.0.0.1 dev.example.com
::1 dev.example.com

我通过从命令行检查$ ping localhost来计算出来，它通常返回:

来自127.0.0.1的回复:bytes=32 time<1ms TTL=128

相反，它现在返回:

回复from::1:时间<1ms

我不知道为什么，但是由于某种原因，IIS Express开始使用IPv6而不是IPv4。