这篇文章本身并不是对这个问题的直接回答。相反，它是一个数据驱动的可扩展基准测试，可以用来比较这个问题的许多答案(以及利用后来更现代的Python版本中添加的新特性的变体)，因此应该有助于确定哪个具有最佳性能。

在一些情况下，我修改了参考答案中的代码，使其与基准测试框架兼容。

首先，以下是目前Python 2和3的最新版本的结果:

Fastest to slowest execution speeds with 32-bit Python 2.7.16
  numpy version 1.16.5
  Test file size: 1,024 KiB
  100 executions, best of 3 repetitions

1                  Tcll (array.array) :   3.8943 secs, rel speed   1.00x,   0.00% slower (262.95 KiB/sec)
2  Vinay Sajip (read all into memory) :   4.1164 secs, rel speed   1.06x,   5.71% slower (248.76 KiB/sec)
3            codeape + iter + partial :   4.1616 secs, rel speed   1.07x,   6.87% slower (246.06 KiB/sec)
4                             codeape :   4.1889 secs, rel speed   1.08x,   7.57% slower (244.46 KiB/sec)
5               Vinay Sajip (chunked) :   4.1977 secs, rel speed   1.08x,   7.79% slower (243.94 KiB/sec)
6           Aaron Hall (Py 2 version) :   4.2417 secs, rel speed   1.09x,   8.92% slower (241.41 KiB/sec)
7                     gerrit (struct) :   4.2561 secs, rel speed   1.09x,   9.29% slower (240.59 KiB/sec)
8                     Rick M. (numpy) :   8.1398 secs, rel speed   2.09x, 109.02% slower (125.80 KiB/sec)
9                           Skurmedel :  31.3264 secs, rel speed   8.04x, 704.42% slower ( 32.69 KiB/sec)

Benchmark runtime (min:sec) - 03:26

Fastest to slowest execution speeds with 32-bit Python 3.8.0
  numpy version 1.17.4
  Test file size: 1,024 KiB
  100 executions, best of 3 repetitions

1  Vinay Sajip + "yield from" + "walrus operator" :   3.5235 secs, rel speed   1.00x,   0.00% slower (290.62 KiB/sec)
2                       Aaron Hall + "yield from" :   3.5284 secs, rel speed   1.00x,   0.14% slower (290.22 KiB/sec)
3         codeape + iter + partial + "yield from" :   3.5303 secs, rel speed   1.00x,   0.19% slower (290.06 KiB/sec)
4                      Vinay Sajip + "yield from" :   3.5312 secs, rel speed   1.00x,   0.22% slower (289.99 KiB/sec)
5      codeape + "yield from" + "walrus operator" :   3.5370 secs, rel speed   1.00x,   0.38% slower (289.51 KiB/sec)
6                          codeape + "yield from" :   3.5390 secs, rel speed   1.00x,   0.44% slower (289.35 KiB/sec)
7                                      jfs (mmap) :   4.0612 secs, rel speed   1.15x,  15.26% slower (252.14 KiB/sec)
8              Vinay Sajip (read all into memory) :   4.5948 secs, rel speed   1.30x,  30.40% slower (222.86 KiB/sec)
9                        codeape + iter + partial :   4.5994 secs, rel speed   1.31x,  30.54% slower (222.64 KiB/sec)
10                                        codeape :   4.5995 secs, rel speed   1.31x,  30.54% slower (222.63 KiB/sec)
11                          Vinay Sajip (chunked) :   4.6110 secs, rel speed   1.31x,  30.87% slower (222.08 KiB/sec)
12                      Aaron Hall (Py 2 version) :   4.6292 secs, rel speed   1.31x,  31.38% slower (221.20 KiB/sec)
13                             Tcll (array.array) :   4.8627 secs, rel speed   1.38x,  38.01% slower (210.58 KiB/sec)
14                                gerrit (struct) :   5.0816 secs, rel speed   1.44x,  44.22% slower (201.51 KiB/sec)
15                 Rick M. (numpy) + "yield from" :  11.8084 secs, rel speed   3.35x, 235.13% slower ( 86.72 KiB/sec)
16                                      Skurmedel :  11.8806 secs, rel speed   3.37x, 237.18% slower ( 86.19 KiB/sec)
17                                Rick M. (numpy) :  13.3860 secs, rel speed   3.80x, 279.91% slower ( 76.50 KiB/sec)

Benchmark runtime (min:sec) - 04:47

我还用一个更大的10mib测试文件运行它(运行了将近一个小时)，得到的性能结果与上面所示的相当。

下面是用来做基准测试的代码:

from __future__ import print_function
import array
import atexit
from collections import deque, namedtuple
import io
from mmap import ACCESS_READ, mmap
import numpy as np
from operator import attrgetter
import os
import random
import struct
import sys
import tempfile
from textwrap import dedent
import time
import timeit
import traceback

try:
    xrange
except NameError:  # Python 3
    xrange = range


class KiB(int):
    """ KibiBytes - multiples of the byte units for quantities of information. """
    def __new__(self, value=0):
        return 1024*value


BIG_TEST_FILE = 1  # MiBs or 0 for a small file.
SML_TEST_FILE = KiB(64)
EXECUTIONS = 100  # Number of times each "algorithm" is executed per timing run.
TIMINGS = 3  # Number of timing runs.
CHUNK_SIZE = KiB(8)
if BIG_TEST_FILE:
    FILE_SIZE = KiB(1024) * BIG_TEST_FILE
else:
    FILE_SIZE = SML_TEST_FILE  # For quicker testing.

# Common setup for all algorithms -- prefixed to each algorithm's setup.
COMMON_SETUP = dedent("""
    # Make accessible in algorithms.
    from __main__ import array, deque, get_buffer_size, mmap, np, struct
    from __main__ import ACCESS_READ, CHUNK_SIZE, FILE_SIZE, TEMP_FILENAME
    from functools import partial
    try:
        xrange
    except NameError:  # Python 3
        xrange = range
""")


def get_buffer_size(path):
    """ Determine optimal buffer size for reading files. """
    st = os.stat(path)
    try:
        bufsize = st.st_blksize # Available on some Unix systems (like Linux)
    except AttributeError:
        bufsize = io.DEFAULT_BUFFER_SIZE
    return bufsize

# Utility primarily for use when embedding additional algorithms into benchmark.
VERIFY_NUM_READ = """
    # Verify generator reads correct number of bytes (assumes values are correct).
    bytes_read = sum(1 for _ in file_byte_iterator(TEMP_FILENAME))
    assert bytes_read == FILE_SIZE, \
           'Wrong number of bytes generated: got {:,} instead of {:,}'.format(
                bytes_read, FILE_SIZE)
"""

TIMING = namedtuple('TIMING', 'label, exec_time')

class Algorithm(namedtuple('CodeFragments', 'setup, test')):

    # Default timeit "stmt" code fragment.
    _TEST = """
        #for b in file_byte_iterator(TEMP_FILENAME):  # Loop over every byte.
        #    pass  # Do stuff with byte...
        deque(file_byte_iterator(TEMP_FILENAME), maxlen=0)  # Data sink.
    """

    # Must overload __new__ because (named)tuples are immutable.
    def __new__(cls, setup, test=None):
        """ Dedent (unindent) code fragment string arguments.
        Args:
          `setup` -- Code fragment that defines things used by `test` code.
                     In this case it should define a generator function named
                     `file_byte_iterator()` that will be passed that name of a test file
                     of binary data. This code is not timed.
          `test` -- Code fragment that uses things defined in `setup` code.
                    Defaults to _TEST. This is the code that's timed.
        """
        test =  cls._TEST if test is None else test  # Use default unless one is provided.

        # Uncomment to replace all performance tests with one that verifies the correct
        # number of bytes values are being generated by the file_byte_iterator function.
        #test = VERIFY_NUM_READ

        return tuple.__new__(cls, (dedent(setup), dedent(test)))


algorithms = {

    'Aaron Hall (Py 2 version)': Algorithm("""
        def file_byte_iterator(path):
            with open(path, "rb") as file:
                callable = partial(file.read, 1024)
                sentinel = bytes() # or b''
                for chunk in iter(callable, sentinel):
                    for byte in chunk:
                        yield byte
    """),

    "codeape": Algorithm("""
        def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
            with open(filename, "rb") as f:
                while True:
                    chunk = f.read(chunksize)
                    if chunk:
                        for b in chunk:
                            yield b
                    else:
                        break
    """),

    "codeape + iter + partial": Algorithm("""
        def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
            with open(filename, "rb") as f:
                for chunk in iter(partial(f.read, chunksize), b''):
                    for b in chunk:
                        yield b
    """),

    "gerrit (struct)": Algorithm("""
        def file_byte_iterator(filename):
            with open(filename, "rb") as f:
                fmt = '{}B'.format(FILE_SIZE)  # Reads entire file at once.
                for b in struct.unpack(fmt, f.read()):
                    yield b
    """),

    'Rick M. (numpy)': Algorithm("""
        def file_byte_iterator(filename):
            for byte in np.fromfile(filename, 'u1'):
                yield byte
    """),

    "Skurmedel": Algorithm("""
        def file_byte_iterator(filename):
            with open(filename, "rb") as f:
                byte = f.read(1)
                while byte:
                    yield byte
                    byte = f.read(1)
    """),

    "Tcll (array.array)": Algorithm("""
        def file_byte_iterator(filename):
            with open(filename, "rb") as f:
                arr = array.array('B')
                arr.fromfile(f, FILE_SIZE)  # Reads entire file at once.
                for b in arr:
                    yield b
    """),

    "Vinay Sajip (read all into memory)": Algorithm("""
        def file_byte_iterator(filename):
            with open(filename, "rb") as f:
                bytes_read = f.read()  # Reads entire file at once.
            for b in bytes_read:
                yield b
    """),

    "Vinay Sajip (chunked)": Algorithm("""
        def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
            with open(filename, "rb") as f:
                chunk = f.read(chunksize)
                while chunk:
                    for b in chunk:
                        yield b
                    chunk = f.read(chunksize)
    """),

}  # End algorithms

#
# Versions of algorithms that will only work in certain releases (or better) of Python.
#
if sys.version_info >= (3, 3):
    algorithms.update({

        'codeape + iter + partial + "yield from"': Algorithm("""
            def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
                with open(filename, "rb") as f:
                    for chunk in iter(partial(f.read, chunksize), b''):
                        yield from chunk
        """),

        'codeape + "yield from"': Algorithm("""
            def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
                with open(filename, "rb") as f:
                    while True:
                        chunk = f.read(chunksize)
                        if chunk:
                            yield from chunk
                        else:
                            break
        """),

        "jfs (mmap)": Algorithm("""
            def file_byte_iterator(filename):
                with open(filename, "rb") as f, \
                     mmap(f.fileno(), 0, access=ACCESS_READ) as s:
                    yield from s
        """),

        'Rick M. (numpy) + "yield from"': Algorithm("""
            def file_byte_iterator(filename):
            #    data = np.fromfile(filename, 'u1')
                yield from np.fromfile(filename, 'u1')
        """),

        'Vinay Sajip + "yield from"': Algorithm("""
            def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
                with open(filename, "rb") as f:
                    chunk = f.read(chunksize)
                    while chunk:
                        yield from chunk  # Added in Py 3.3
                        chunk = f.read(chunksize)
        """),

    })  # End Python 3.3 update.

if sys.version_info >= (3, 5):
    algorithms.update({

        'Aaron Hall + "yield from"': Algorithm("""
            from pathlib import Path

            def file_byte_iterator(path):
                ''' Given a path, return an iterator over the file
                    that lazily loads the file.
                '''
                path = Path(path)
                bufsize = get_buffer_size(path)

                with path.open('rb') as file:
                    reader = partial(file.read1, bufsize)
                    for chunk in iter(reader, bytes()):
                        yield from chunk
        """),

    })  # End Python 3.5 update.

if sys.version_info >= (3, 8, 0):
    algorithms.update({

        'Vinay Sajip + "yield from" + "walrus operator"': Algorithm("""
            def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
                with open(filename, "rb") as f:
                    while chunk := f.read(chunksize):
                        yield from chunk  # Added in Py 3.3
        """),

        'codeape + "yield from" + "walrus operator"': Algorithm("""
            def file_byte_iterator(filename, chunksize=CHUNK_SIZE):
                with open(filename, "rb") as f:
                    while chunk := f.read(chunksize):
                        yield from chunk
        """),

    })  # End Python 3.8.0 update.update.


#### Main ####

def main():
    global TEMP_FILENAME

    def cleanup():
        """ Clean up after testing is completed. """
        try:
            os.remove(TEMP_FILENAME)  # Delete the temporary file.
        except Exception:
            pass

    atexit.register(cleanup)

    # Create a named temporary binary file of pseudo-random bytes for testing.
    fd, TEMP_FILENAME = tempfile.mkstemp('.bin')
    with os.fdopen(fd, 'wb') as file:
         os.write(fd, bytearray(random.randrange(256) for _ in range(FILE_SIZE)))

    # Execute and time each algorithm, gather results.
    start_time = time.time()  # To determine how long testing itself takes.

    timings = []
    for label in algorithms:
        try:
            timing = TIMING(label,
                            min(timeit.repeat(algorithms[label].test,
                                              setup=COMMON_SETUP + algorithms[label].setup,
                                              repeat=TIMINGS, number=EXECUTIONS)))
        except Exception as exc:
            print('{} occurred timing the algorithm: "{}"\n  {}'.format(
                    type(exc).__name__, label, exc))
            traceback.print_exc(file=sys.stdout)  # Redirect to stdout.
            sys.exit(1)
        timings.append(timing)

    # Report results.
    print('Fastest to slowest execution speeds with {}-bit Python {}.{}.{}'.format(
            64 if sys.maxsize > 2**32 else 32, *sys.version_info[:3]))
    print('  numpy version {}'.format(np.version.full_version))
    print('  Test file size: {:,} KiB'.format(FILE_SIZE // KiB(1)))
    print('  {:,d} executions, best of {:d} repetitions'.format(EXECUTIONS, TIMINGS))
    print()

    longest = max(len(timing.label) for timing in timings)  # Len of longest identifier.
    ranked = sorted(timings, key=attrgetter('exec_time')) # Sort so fastest is first.
    fastest = ranked[0].exec_time
    for rank, timing in enumerate(ranked, 1):
        print('{:<2d} {:>{width}} : {:8.4f} secs, rel speed {:6.2f}x, {:6.2f}% slower '
              '({:6.2f} KiB/sec)'.format(
                    rank,
                    timing.label, timing.exec_time, round(timing.exec_time/fastest, 2),
                    round((timing.exec_time/fastest - 1) * 100, 2),
                    (FILE_SIZE/timing.exec_time) / KiB(1),  # per sec.
                    width=longest))
    print()
    mins, secs = divmod(time.time()-start_time, 60)
    print('Benchmark runtime (min:sec) - {:02d}:{:02d}'.format(int(mins),
                                                               int(round(secs))))

main()

在Python中读取二进制文件并遍历每个字节

Python 3.5的新功能是pathlib模块，它有一个方便的方法，专门以字节的形式读取文件，允许我们遍历字节。我认为这是一个体面的答案(如果快速和肮脏):

import pathlib

for byte in pathlib.Path(path).read_bytes():
    print(byte)

有趣的是，这是提到pathlib的唯一答案。

在Python 2中，你可能会这样做(正如Vinay Sajip也建议的那样):

with open(path, 'b') as file:
    for byte in file.read():
        print(byte)

如果文件太大，无法在内存中遍历，则使用iter函数和可调用的哨兵签名(Python 2版本)对其进行分块:

with open(path, 'b') as file:
    callable = lambda: file.read(1024)
    sentinel = bytes() # or b''
    for chunk in iter(callable, sentinel): 
        for byte in chunk:
            print(byte)

(其他几个答案也提到了这一点，但很少提供合理的读取大小。)

用于大文件或缓冲/交互式读取的最佳实践

让我们创建一个函数来实现这一点，包括Python 3.5+标准库的惯用用法:

from pathlib import Path
from functools import partial
from io import DEFAULT_BUFFER_SIZE

def file_byte_iterator(path):
    """given a path, return an iterator over the file
    that lazily loads the file
    """
    path = Path(path)
    with path.open('rb') as file:
        reader = partial(file.read1, DEFAULT_BUFFER_SIZE)
        file_iterator = iter(reader, bytes())
        for chunk in file_iterator:
            yield from chunk

注意，我们使用file.read1。文件。read块，直到它得到它或EOF请求的所有字节。文件。Read1允许我们避免阻塞，因此它可以更快地返回。其他答案也没有提到这一点。

最佳实践使用的演示:

让我们创建一个带有兆字节(实际上是mebibyte)伪随机数据的文件:

import random
import pathlib
path = 'pseudorandom_bytes'
pathobj = pathlib.Path(path)

pathobj.write_bytes(
  bytes(random.randint(0, 255) for _ in range(2**20)))

现在让我们遍历它并在内存中物化它:

>>> l = list(file_byte_iterator(path))
>>> len(l)
1048576

我们可以检查数据的任何部分，例如，最后100字节和前100字节:

>>> l[-100:]
[208, 5, 156, 186, 58, 107, 24, 12, 75, 15, 1, 252, 216, 183, 235, 6, 136, 50, 222, 218, 7, 65, 234, 129, 240, 195, 165, 215, 245, 201, 222, 95, 87, 71, 232, 235, 36, 224, 190, 185, 12, 40, 131, 54, 79, 93, 210, 6, 154, 184, 82, 222, 80, 141, 117, 110, 254, 82, 29, 166, 91, 42, 232, 72, 231, 235, 33, 180, 238, 29, 61, 250, 38, 86, 120, 38, 49, 141, 17, 190, 191, 107, 95, 223, 222, 162, 116, 153, 232, 85, 100, 97, 41, 61, 219, 233, 237, 55, 246, 181]
>>> l[:100]
[28, 172, 79, 126, 36, 99, 103, 191, 146, 225, 24, 48, 113, 187, 48, 185, 31, 142, 216, 187, 27, 146, 215, 61, 111, 218, 171, 4, 160, 250, 110, 51, 128, 106, 3, 10, 116, 123, 128, 31, 73, 152, 58, 49, 184, 223, 17, 176, 166, 195, 6, 35, 206, 206, 39, 231, 89, 249, 21, 112, 168, 4, 88, 169, 215, 132, 255, 168, 129, 127, 60, 252, 244, 160, 80, 155, 246, 147, 234, 227, 157, 137, 101, 84, 115, 103, 77, 44, 84, 134, 140, 77, 224, 176, 242, 254, 171, 115, 193, 29]

对于二进制文件，不要逐行迭代

不要做下面的操作——这将拖动任意大小的块，直到它变成一个换行符——当块太小时速度太慢，而且可能也太大了:

    with open(path, 'rb') as file:
        for chunk in file: # text newline iteration - not for bytes
            yield from chunk

以上只适用于语义上人类可读的文本文件(如纯文本、代码、标记、markdown等)。基本上任何ascii, utf，拉丁语等…编码)，您应该打开没有'b'标志。

如果要读取大量二进制数据，可能需要考虑struct模块。它被记录为“在C和Python类型之间”转换，但当然，字节就是字节，它们是否被创建为C类型并不重要。例如，如果你的二进制数据包含两个2字节整数和一个4字节整数，你可以这样读取它们(例子来自struct文档):

>>> struct.unpack('hhl', b'\x00\x01\x00\x02\x00\x00\x00\x03')
(1, 2, 3)

您可能会发现这比显式遍历文件内容更方便、更快，或者两者兼而有之。

如果文件不是太大，在内存中保存它是一个问题:

with open("filename", "rb") as f:
    bytes_read = f.read()
for b in bytes_read:
    process_byte(b)

其中process_byte表示希望对传入的字节执行的一些操作。

如果你想一次处理一个数据块:

with open("filename", "rb") as f:
    bytes_read = f.read(CHUNKSIZE)
    while bytes_read:
        for b in bytes_read:
            process_byte(b)
        bytes_read = f.read(CHUNKSIZE)

with语句在Python 2.5及更高版本中可用。

在尝试了以上所有方法并使用@Aaron Hall的答案后，我在一台运行windows 10, 8gb RAM和Python 3.5 32位的计算机上得到了一个~ 90mb的文件的内存错误。我的一位同事推荐我使用numpy，它的效果非常好。

到目前为止，读取整个二进制文件(我测试过)的最快速度是:

import numpy as np

file = "binary_file.bin"
data = np.fromfile(file, 'u1')

参考

比目前任何方法都要快。希望它能帮助到一些人!

对于大尺寸，我认为使用生成器不会不好，这个答案是为了读取像文件这样的东西，虽然@codeapp有一个类似的答案，我认为删除内部循环会更有意义。

def read_chunk(file_object, chunk_size=125):
    while True:
        file =  file_object.read(chunk_size)
        if not file:
            break
        yield file


#sample use 
buffer = io.BytesIO()
file = open('myfile', 'r')
for chunk in read_chunk(file):
    buffer.write(chunk)
buffer.seek(0)
// save the file or do whatever you want here

你仍然可以使用它作为一个正常的列表，我不认为这是任何用途，但是

file_list = list(read_chunk(file, chunk_size=10000))
for i in file_list:
    # do something

然后得到每个数据块的索引

for index, chunk in enumurate(read_chunk(file, chunk_size=10000)):
    #use the index as a number index
    # you can try and get the size of each chunk with this 
    length = len(chunk)

注意，要注意文件的大小，chunk_size总是以字节为单位。