更简单、更符合逻辑的做法是:

- (UIView *)tableView:(UITableView *)tableView viewForFooterInSection:(NSInteger)section
{
    return [[UIView alloc] initWithFrame:CGRectZero];
}

在大多数情况下，您不希望只看到最后一个表视图单元格分隔符。这种方法只删除了最后一个表格视图单元格分隔符，你不需要考虑自动布局问题(即旋转设备)或硬编码值来设置分隔符嵌入。

在使用iOS 8.4的Swift中:

/*
    Tells the delegate that the table view is about to draw a cell for a particular row. (optional)
*/
override func tableView(tableView: UITableView,
                        willDisplayCell cell: UITableViewCell,
                        forRowAtIndexPath indexPath: NSIndexPath)
{
    if indexPath.row == 3 {
        // Hiding separator line for only one specific UITableViewCell
        cell.separatorInset = UIEdgeInsetsMake(0, cell.bounds.size.width, 0, 0)
    }
}

Note: this snippet above will work on UITableView using dynamic cells. The only problem that you can encounter is when you use static cells with categories, a separator type different than none and a grouped style for the table view. In fact, in this particular case it will not hide the last cell of each category. For overcoming that, the solution that I found was to set the cell separator (through IB) to none and then creating and adding manually (through code) your line view to each cell. For an example, please check the snippet below:

/*
Tells the delegate that the table view is about to draw a cell for a particular row. (optional)
*/
override func tableView(tableView: UITableView,
    willDisplayCell cell: UITableViewCell,
    forRowAtIndexPath indexPath: NSIndexPath)
{
    // Row 2 at Section 2
    if indexPath.row == 1 && indexPath.section == 1 {
        // Hiding separator line for one specific UITableViewCell
        cell.separatorInset = UIEdgeInsetsMake(0, cell.bounds.size.width, 0, 0)

        // Here we add a line at the bottom of the cell (e.g. here at the second row of the second section).
        let additionalSeparatorThickness = CGFloat(1)
        let additionalSeparator = UIView(frame: CGRectMake(0,
            cell.frame.size.height - additionalSeparatorThickness,
            cell.frame.size.width,
            additionalSeparatorThickness))
        additionalSeparator.backgroundColor = UIColor.redColor()
        cell.addSubview(additionalSeparator)
    }
}

来跟进Hiren的回答。

在ViewDidLoad和下面一行:

self.tableView.separatorStyle = UITableViewCellSeparatorStyleNone;

或者，如果你正在使用XIB或storyboard，将“separator”更改为“none”:

在CellForRowAtIndexPath中添加这个:

CGFloat separatorInset; // Separator x position 
CGFloat separatorHeight; 
CGFloat separatorWidth; 
CGFloat separatorY; 
UIImageView *separator;
UIColor *separatorBGColor;

separatorY      = cell.frame.size.height;
separatorHeight = (1.0 / [UIScreen mainScreen].scale);  // This assures you to have a 1px line height whatever the screen resolution
separatorWidth  = cell.frame.size.width;
separatorInset  = 15.0f;
separatorBGColor  = [UIColor colorWithRed: 204.0/255.0 green: 204.0/255.0 blue: 204.0/255.0 alpha:1.0];

separator = [[UIImageView alloc] initWithFrame:CGRectMake(separatorInset, separatorY, separatorWidth,separatorHeight)];
separator.backgroundColor = separatorBGColor;
[cell addSubView: separator];

这是一个结果的例子，我显示一个动态单元格的tableview(但只有一个内容)。结果是，只有一个有分隔符，而不是所有的“虚拟”tableview自动添加填充屏幕。

编辑:对于那些不经常阅读注释的人来说，实际上有一种更好的方法，只需几行代码:

override func viewDidLoad() {
    super.viewDidLoad()
    tableView.tableFooterView = UIView()
}

使用Swift 3并采用最快的黑客方法，您可以使用扩展来改进代码:

extension UITableViewCell {

    var isSeparatorHidden: Bool {
        get {
            return self.separatorInset.right != 0
        }
        set {
            if newValue {
                self.separatorInset = UIEdgeInsetsMake(0, self.bounds.size.width, 0, 0)
            } else {
                self.separatorInset = UIEdgeInsetsMake(0, 0, 0, 0)
            }
        }
    }

}

然后，当你配置单元格时:

func tableView(_ tableView: UITableView, cellForRowAt indexPath: IndexPath) -> UITableViewCell {
    let cell = collectionView.dequeueReusableCell(withReuseIdentifier: "identifier", for: indexPath)
    switch indexPath.row {
       case 3:
          cell.isSeparatorHidden = true
       default:
          cell.isSeparatorHidden = false
    }
    return cell
}

func tableView(_ tableView: UITableView, didSelectRowAt indexPath: IndexPath) {
    let cell = tableView.cellForRow(at: indexPath)
    if cell.isSeparatorHidden { 
       // do stuff
    }
}

我的要求是将分隔符隐藏在第4和第5单元格之间。我通过

    -(void)tableView:(UITableView *)tableView willDisplayCell:(UITableViewCell *)cell forRowAtIndexPath:(NSIndexPath *)indexPath {
    if(indexPath.row == 3)
    {
        cell.separatorInset = UIEdgeInsetsMake(0, cell.bounds.size.width, 0, 0);
    }
}

如果接受的答案不成立，你可以试试这个:

- (CGFloat)tableView:(UITableView *)tableView heightForFooterInSection:(NSInteger)section {
    return 0.01f; }

太棒了;)