这对我很管用。它与前面的答案相似，但是包的路径不同。

Sudo easy_install -m sudo rm -rf /Library/Python/2.7/site-packages/.egg

平台:MacOS High Sierra 10.13.3版本

在尝试卸载随时间安装的许多随机Python包时遇到了这个问题。

利用这篇文章中的信息，我得出了以下结论:

cat package_list | xargs -n1 sudo pip uninstall -y

从virtualenv中的pip冻结中清理package_list (awk)。

删除几乎所有Python包:

yolk -l | cut -f 1 -d " " | grep -v "setuptools|pip|ETC.." | xargs -n1 pip uninstall -y

If the problem is a serious-enough annoyance to you, you might consider virtualenv. It allows you to create an environment that encapsulates python libraries. You install packages there rather than in the global site-packages directory. Any scripts you run in that environment have access to those packages (and optionally, your global ones as well). I use this a lot when evaluating packages that I am not sure I want/need to install globally. If you decide you don't need the package, it's easy enough to just blow that virtual environment away. It's pretty easy to use. Make a new env:

$>virtualenv /path/to/your/new/ENV

Virtual_envt在新环境中为你安装setuptools，所以你可以这样做:

$>ENV/bin/easy_install

您甚至可以创建自己的boostrap脚本来设置新环境。因此，用一个命令，你就可以创建一个新的虚拟env，比如python 2.6, psycopg2和默认安装的django(如果你愿意，你也可以安装env特定版本的python)。

网上有几个来源建议使用-m选项重新安装包，然后删除lib/中的.egg文件和bin/中的二进制文件。此外，关于此setuptools问题的讨论可以在python错误跟踪器中作为setuptools问题21找到。

编辑:添加了python bug跟踪器的链接。

官方(?)说明:http://peak.telecommunity.com/DevCenter/EasyInstall#uninstalling-packages

If you have replaced a package with another version, then you can just delete the package(s) you don't need by deleting the PackageName-versioninfo.egg file or directory (found in the installation directory). If you want to delete the currently installed version of a package (or all versions of a package), you should first run: easy_install -mxN PackageName This will ensure that Python doesn't continue to search for a package you're planning to remove. After you've done this, you can safely delete the .egg files or directories, along with any scripts you wish to remove.

我只删除这个文件:easy-install.pth 工作，休息PIP安装django==1.3.7