这是由于您的代码所依赖的类文件在编译时存在，但在运行时没有找到。寻找构建时和运行时类路径的差异。

确保在module:app和module:lib中匹配:

android {
    compileSdkVersion 23
    buildToolsVersion '22.0.1'
    packagingOptions {
    }

    defaultConfig {
        minSdkVersion 17
        targetSdkVersion 23
        versionCode 11
        versionName "2.1"
    }

当我试图在Tomcat/JBOSS服务器上部署应用程序时，我得到了NoClassDefFoundError。我尝试了不同的依赖关系来解决这个问题，但总是得到相同的错误。标记所有javax。*依赖提供在pom.xml，和战争字面上没有依赖。但这个问题还是不断出现。

最终意识到src/main/webapps/WEB-INF/classes有类文件夹被复制到我的战争，所以不是编译类，这个类被复制，因此没有依赖改变解决问题。

因此要小心，如果任何以前编译的数据被复制，删除类文件夹和新的编译后，它工作!..

当我没有在项目的Java Build Path中的“Order and export”选项卡上导出一个类时，我得到了NoClassDefFound错误。确保在添加到项目构建路径的任何依赖项的“Order and Export”选项卡中添加一个复选标记。请参见Eclipse警告:XXXXXXXXXXX.jar将不会被导出或发布。可能会导致运行时ClassNotFoundExceptions。

更新[https://www.infoq.com/articles/single-file-execution-java11/]:

在Java SE 11中，可以选择启动单个源代码文件 直接，不需要中间编译。为了方便大家， 所以像你这样的新手不需要运行javac + Java(当然， 让他们感到困惑)。

Java中的NoClassDefFoundError

定义:

Java虚拟机无法在运行时找到在编译时可用的特定类。 如果一个类在编译时存在，但在运行时在java类路径中不可用。

例子:

The class is not in Classpath, there is no sure shot way of knowing it but many times you can just have a look to print System.getproperty("java.classpath") and it will print the classpath from there you can at least get an idea of your actual runtime classpath. A simple example of NoClassDefFoundError is class belongs to a missing JAR file or JAR was not added into classpath or sometimes jar's name has been changed by someone like in my case one of my colleagues has changed tibco.jar into tibco_v3.jar and the program is failing with java.lang.NoClassDefFoundError and I were wondering what's wrong. Just try to run with explicitly -classpath option with the classpath you think will work and if it's working then it's a sure short sign that someone is overriding java classpath. Permission issue on JAR file can also cause NoClassDefFoundError in Java. Typo on XML Configuration can also cause NoClassDefFoundError in Java. when your compiled class which is defined in a package, doesn’t present in the same package while loading like in the case of JApplet it will throw NoClassDefFoundError in Java.

可能的解决方式:

The class is not available in Java Classpath. If you are working in J2EE environment than the visibility of Class among multiple Classloader can also cause java.lang.NoClassDefFoundError, see examples and scenario section for detailed discussion. Check for java.lang.ExceptionInInitializerError in your log file. NoClassDefFoundError due to the failure of static initialization is quite common. Because NoClassDefFoundError is a subclass of java.lang.LinkageError it can also come if one of it dependency like native library may not available. Any start-up script is overriding Classpath environment variable. You might be running your program using jar command and class was not defined in manifest file's ClassPath attribute.

资源:

3种方法解决NoClassDefFoundError

noclassdeffounderror问题模式