使用谷歌闭包:

你可以使用ccsom模块:

goog.require('goog.cssom');
var css_node = goog.cssom.addCssText('.cssClass { color: #F00; }');

当将css节点放入文档头时，javascript代码试图跨浏览器。

以下是Vishwanath的解决方案，稍微写了一些注释:

function setStyle(cssRules, aSelector, aStyle){
    for(var i = 0; i < cssRules.length; i++) {
        if(cssRules[i].selectorText && cssRules[i].selectorText.toLowerCase() == aSelector.toLowerCase()) {
            cssRules[i].style.cssText = aStyle;
            return true;
        }
    }
    return false;
}

function createCSSSelector(selector, style) {
    var doc = document;
    var allSS = doc.styleSheets;
    if(!allSS) return;

    var headElts = doc.getElementsByTagName("head");
    if(!headElts.length) return;

    var styleSheet, media, iSS = allSS.length; // scope is global in a function
    /* 1. search for media == "screen" */
    while(iSS){ --iSS;
        if(allSS[iSS].disabled) continue; /* dont take into account the disabled stylesheets */
        media = allSS[iSS].media;
        if(typeof media == "object")
            media = media.mediaText;
        if(media == "" || media=='all' || media.indexOf("screen") != -1){
            styleSheet = allSS[iSS];
            iSS = -1;   // indication that media=="screen" was found (if not, then iSS==0)
            break;
        }
    }

    /* 2. if not found, create one */
    if(iSS != -1) {
        var styleSheetElement = doc.createElement("style");
        styleSheetElement.type = "text/css";
        headElts[0].appendChild(styleSheetElement);
        styleSheet = doc.styleSheets[allSS.length]; /* take the new stylesheet to add the selector and the style */
    }

    /* 3. add the selector and style */
    switch (typeof styleSheet.media) {
    case "string":
        if(!setStyle(styleSheet.rules, selector, style));
            styleSheet.addRule(selector, style);
        break;
    case "object":
        if(!setStyle(styleSheet.cssRules, selector, style));
            styleSheet.insertRule(selector + "{" + style + "}", styleSheet.cssRules.length);
        break;
    }

function createCSSClass(selector, style, hoverstyle) 
{
    if (!document.styleSheets) 
    {
        return;
    }

    if (document.getElementsByTagName("head").length == 0) 
    {

        return;
    }
    var stylesheet;
    var mediaType;
    if (document.styleSheets.length > 0) 
    {
        for (i = 0; i < document.styleSheets.length; i++) 
        {
            if (document.styleSheets[i].disabled) 
            {
                continue;
            }
            var media = document.styleSheets[i].media;
            mediaType = typeof media;

            if (mediaType == "string") 
            {
                if (media == "" || (media.indexOf("screen") != -1)) 
                {
                    styleSheet = document.styleSheets[i];
                }
            } 
            else if (mediaType == "object") 
            {
                if (media.mediaText == "" || (media.mediaText.indexOf("screen") != -1)) 
                {
                    styleSheet = document.styleSheets[i];
                }
            }

            if (typeof styleSheet != "undefined") 
            {
                break;
            }
        }
    }

    if (typeof styleSheet == "undefined") {
        var styleSheetElement = document.createElement("style");
        styleSheetElement.type = "text/css";
        document.getElementsByTagName("head")[0].appendChild(styleSheetElement);
        for (i = 0; i < document.styleSheets.length; i++) {
            if (document.styleSheets[i].disabled) {
                continue;
            }
            styleSheet = document.styleSheets[i];
        }

        var media = styleSheet.media;
        mediaType = typeof media;
    }

    if (mediaType == "string") {
        for (i = 0; i < styleSheet.rules.length; i++) 
        {
            if (styleSheet.rules[i].selectorText.toLowerCase() == selector.toLowerCase()) 
            {
                styleSheet.rules[i].style.cssText = style;
                return;
            }
        }

        styleSheet.addRule(selector, style);
    }
    else if (mediaType == "object") 
    {
        for (i = 0; i < styleSheet.cssRules.length; i++) 
        {
            if (styleSheet.cssRules[i].selectorText.toLowerCase() == selector.toLowerCase()) 
            {
                styleSheet.cssRules[i].style.cssText = style;
                return;
            }
        }

        if (hoverstyle != null) 
        {
            styleSheet.insertRule(selector + "{" + style + "}", 0);
            styleSheet.insertRule(selector + ":hover{" + hoverstyle + "}", 1);
        }
        else 
        {
            styleSheet.insertRule(selector + "{" + style + "}", 0);
        }
    }
}





createCSSClass(".modalPopup  .header",
                                 " background-color: " + lightest + ";" +
                                  "height: 10%;" +
                                  "color: White;" +
                                  "line-height: 30px;" +
                                  "text-align: center;" +
                                  " width: 100%;" +
                                  "font-weight: bold; ", null);

简单地说，这在“所有浏览器”(特别是IE8/7)上都兼容:

function createClass(name,rules){
    var style = document.createElement('style');
    style.type = 'text/css';
    document.getElementsByTagName('head')[0].appendChild(style);
    if(!(style.sheet||{}).insertRule) 
        (style.styleSheet || style.sheet).addRule(name, rules);
    else
        style.sheet.insertRule(name+"{"+rules+"}",0);
}
createClass('.whatever',"background-color: green;");

最后一位将类应用于一个元素:

function applyClass(name,element,doRemove){
    if(typeof element.valueOf() == "string"){
        element = document.getElementById(element);
    }
    if(!element) return;
    if(doRemove){
        element.className = element.className.replace(new RegExp("\\b" + name + "\\b","g"));
    }else{      
        element.className = element.className + " " + name;
    }
}

这里还有一个小测试页面:https://gist.github.com/shadybones/9816763

关键的一点是，样式元素有一个“styleSheet”/“sheet”属性，你可以用它来添加/删除规则。

https://jsfiddle.net/xk6Ut/256/

在JavaScript中动态创建和更新CSS类的一个选项:

使用样式元素创建CSS节 使用样式元素的ID，以便我们可以更新CSS 类

…

function writeStyles(styleName, cssText) {
    var styleElement = document.getElementById(styleName);
    if (styleElement) 
             document.getElementsByTagName('head')[0].removeChild(
        styleElement);
    styleElement = document.createElement('style');
    styleElement.type = 'text/css';
    styleElement.id = styleName;
    styleElement.innerHTML = cssText;
    document.getElementsByTagName('head')[0].appendChild(styleElement);
}

...

    var cssText = '.testDIV{ height:' + height + 'px !important; }';
    writeStyles('styles_js', cssText)

IE 9。现在可以加载文本文件并设置样式。innerHTML属性。所以本质上你现在可以通过ajax加载一个css文件(并获得回调)，然后像这样设置样式标签内的文本。

这适用于其他浏览器，不确定多久以前。但只要你不需要支持IE8，它就可以工作。

// RESULT: doesn't work in IE8 and below. Works in IE9 and other browsers.
$(document).ready(function() {
    // we want to load the css as a text file and append it with a style.
    $.ajax({
        url:'myCss.css',
        success: function(result) {
            var s = document.createElement('style');
            s.setAttribute('type', 'text/css');
            s.innerHTML = result;
            document.getElementsByTagName("head")[0].appendChild(s);
        },
        fail: function() {
            alert('fail');
        }
    })
});

然后你可以让它取出一个外部文件，比如mycss。css

.myClass { background:#F00; }