删除一个字符或子字符串一次(只删除第一次):

main_string = main_string.replace(sub_str, replace_with, 1)

注意:这里的1可以用任何int替换，表示要替换的出现次数。

使用translate()方法:

>>> s = 'EXAMPLE'
>>> s.translate(None, 'M')
'EXAPLE'

取代:取代特定的位置:

s = s[:pos] + s[(pos+1):]

替换一个特定的字符:

s = s.replace('M','')

def kill_char(string, n): # n = position of which character you want to remove
    begin = string[:n]    # from beginning to n (n not included)
    end = string[n+1:]    # n+1 through end of string
    return begin + end
print kill_char("EXAMPLE", 3)  # "M" removed

我在这里某处见过。

字符串是不可变的。但是你可以把它们转换成一个可变的列表，然后在你改变它之后再把它转换回字符串。

s = "this is a string"

l = list(s)  # convert to list

l[1] = ""    # "delete" letter h (the item actually still exists but is empty)
l[1:2] = []  # really delete letter h (the item is actually removed from the list)
del(l[1])    # another way to delete it

p = l.index("a")  # find position of the letter "a"
del(l[p])         # delete it

s = "".join(l)  # convert back to string

您还可以创建一个新字符串，就像其他人演示的那样，从现有字符串中取出所需字符以外的所有内容。

删除一个字符或子字符串一次(只删除第一次):

main_string = main_string.replace(sub_str, replace_with, 1)

注意:这里的1可以用任何int替换，表示要替换的出现次数。