解决方案不工作的负索引，所以我添加了一个补丁。

String.prototype.replaceAt=function(index, character) {
    if(index>-1) return this.substr(0, index) + character + this.substr(index+character.length);
    else return this.substr(0, this.length+index) + character + this.substr(index+character.length);
    
}

如果你想替换字符串中的字符，你应该创建可变字符串。这些本质上是字符数组。你可以创建一个工厂:

  function MutableString(str) {
    var result = str.split("");
    result.toString = function() {
      return this.join("");
    }
    return result;
  }

然后你可以访问字符，整个数组转换为字符串时使用的字符串:

  var x = MutableString("Hello");
  x[0] = "B"; // yes, we can alter the character
  x.push("!"); // good performance: no new string is created
  var y = "Hi, "+x; // converted to string: "Hi, Bello!"

谢谢你的回答!

我还稍微调整了它，使它更像数组。拼接方法(并考虑了@Ates的笔记):

spliceString=function(string, index, numToDelete, char) {
      return string.substr(0, index) + char + string.substr(index+numToDelete);
   }

var myString="hello world!";
spliceString(myString,myString.lastIndexOf('l'),2,'mhole'); // "hello wormhole!"

这很容易用RegExp实现!

const str = 'Hello RegEx!';
const index = 11;
const replaceWith = 'p';

//'Hello RegEx!'.replace(/^(.{11})(.)/, `$1p`);
str.replace(new RegExp(`^(.{${ index }})(.)`), `$1${ replaceWith }`);

//< "Hello RegExp"

可以使用以下函数替换字符串特定位置的字符或字符串。使用String.prototype.replaceAllMatches()函数替换以下所有匹配案例。

String.prototype.replaceMatch = function(matchkey, replaceStr, matchIndex) {
    var retStr = this, repeatedIndex = 0;
    for (var x = 0; (matchkey != null) && (retStr.indexOf(matchkey) > -1); x++) {
        if (repeatedIndex == 0 && x == 0) {
            repeatedIndex = retStr.indexOf(matchkey);
        } else { // matchIndex > 0
            repeatedIndex = retStr.indexOf(matchkey, repeatedIndex + 1);
        }
        if (x == matchIndex) {
            retStr = retStr.substring(0, repeatedIndex) + replaceStr + retStr.substring(repeatedIndex + (matchkey.length));
            matchkey = null; // To break the loop.
        }
    }
    return retStr;
};

测试:

var str = "yash yas $dfdas.**";

console.log('Index Matched replace : ', str.replaceMatch('as', '*', 2) );
console.log('Index Matched replace : ', str.replaceMatch('y', '~', 1) );

输出:

Index Matched replace :  yash yas $dfd*.**
Index Matched replace :  yash ~as $dfdas.**

你不能。取位置前后的字符并连接成一个新字符串:

var s = "Hello world";
var index = 3;
s = s.substring(0, index) + 'x' + s.substring(index + 1);