有两种方法可以处理这个问题。

1)检查事件。目标结果在你的回调，看看它是否匹配你的父div

var g_ParentDiv;

function OnMouseOut(event) {
    if (event.target != g_ParentDiv) {
        return;
    }
    // handle mouse event here!
};


window.onload = function() {
    g_ParentDiv = document.getElementById("parentdiv");
    g_ParentDiv.onmouseout = OnMouseOut;
};

<div id="parentdiv">
    <img src="childimage.jpg" id="childimg" />
</div>

2)或者使用事件捕获和调用事件。回调函数中的stopPropagation

var g_ParentDiv;

function OnMouseOut(event) {

    event.stopPropagation(); // don't let the event recurse into children

    // handle mouse event here!
};


window.onload = function() {
    g_ParentDiv = document.getElementById("parentdiv");
    g_ParentDiv.addEventListener("mouseout", OnMouseOut, true); // pass true to enable event capturing so parent gets event callback before children
};

<div id="parentdiv">
    <img src="childimage.jpg" id="childimg" />
</div>

感谢阿姆贾德·马萨德，他激励了我。

我有以下解决方案，似乎在IE9, FF和Chrome和代码很短(没有复杂的闭包和横向子东西):

    DIV.onmouseout=function(e){
        // check and loop relatedTarget.parentNode
        // ignore event triggered mouse overing any child element or leaving itself
        var obj=e.relatedTarget;
        while(obj!=null){
            if(obj==this){
                return;
            }
            obj=obj.parentNode;
        }
        // now perform the actual action you want to do only when mouse is leaving the DIV
    }

尝试mouseleave ()

例子:

<div id="parent" mouseleave="function">
   <div id="child">

   </div>
</div>

;)

虽然你提到的解决方案使用jquery， Mouseenter和mouseleave是原生dom事件，所以你可以不使用jquery。

有两种方法可以处理这个问题。

1)检查事件。目标结果在你的回调，看看它是否匹配你的父div

var g_ParentDiv;

function OnMouseOut(event) {
    if (event.target != g_ParentDiv) {
        return;
    }
    // handle mouse event here!
};


window.onload = function() {
    g_ParentDiv = document.getElementById("parentdiv");
    g_ParentDiv.onmouseout = OnMouseOut;
};

<div id="parentdiv">
    <img src="childimage.jpg" id="childimg" />
</div>

2)或者使用事件捕获和调用事件。回调函数中的stopPropagation

var g_ParentDiv;

function OnMouseOut(event) {

    event.stopPropagation(); // don't let the event recurse into children

    // handle mouse event here!
};


window.onload = function() {
    g_ParentDiv = document.getElementById("parentdiv");
    g_ParentDiv.addEventListener("mouseout", OnMouseOut, true); // pass true to enable event capturing so parent gets event callback before children
};

<div id="parentdiv">
    <img src="childimage.jpg" id="childimg" />
</div>

如果你添加(或拥有)一个CSS类或id到父元素，那么你可以这样做:

<div id="parent">
  <div>
  </div>
</div>

JavaScript:
document.getElementById("parent").onmouseout = function(e) {
  e = e ? e : window.event //For IE
  if(e.target.id == "parent") {
    //Do your stuff
  }
}

所以只有当事件在父div上时，才会执行东西。