这对我很有用，

mEditTextSearch.addTextChangedListener(new TextWatcher() {

        @Override
        public void onTextChanged(CharSequence s, int start, int before, int count) {
            if(s.length()>0){
                mEditTextSearch.setCompoundDrawablesWithIntrinsicBounds(null, null, getResources().getDrawable(android.R.drawable.ic_delete), null);
            }else{
                mEditTextSearch.setCompoundDrawablesWithIntrinsicBounds(null, null, getResources().getDrawable(R.drawable.abc_ic_search), null);
            }
        }
        @Override
        public void beforeTextChanged(CharSequence s, int start, int count, int after) {
        }
        @Override
        public void afterTextChanged(Editable s) {
        }
    });
    mEditTextSearch.setOnTouchListener(new OnTouchListener() {
        @SuppressLint("ClickableViewAccessibility")
        @Override
        public boolean onTouch(View v, MotionEvent event) {
            if(event.getAction() == MotionEvent.ACTION_UP) {
                if(mEditTextSearch.getCompoundDrawables()[2]!=null){
                    if(event.getX() >= (mEditTextSearch.getRight()- mEditTextSearch.getLeft() - mEditTextSearch.getCompoundDrawables()[2].getBounds().width())) {
                        mEditTextSearch.setText("");
                    }
                }
            }
            return false;
        }
    });

我是这样做的

            <RelativeLayout
                android:layout_width="match_parent"
                android:layout_height="wrap_content">

                <android.support.design.widget.TextInputLayout
                    android:id="@+id/til_text"

                    android:layout_width="match_parent"
                    android:layout_height="wrap_content"
                    android:layout_alignParentTop="true"
                    android:textColorHint="@color/colorSilver">

                    <android.support.design.widget.TextInputEditText
                        android:id="@+id/tiet_text"
                        android:layout_width="match_parent"
                        android:layout_height="wrap_content"
                        android:gravity="top|left"
                        android:hint="@string/rep_hint"
                        android:inputType="textMultiLine"
                        android:maxLines="3"
                        android:drawableEnd="@drawable/ic_attach_photo"
                        android:drawablePadding="5dp"
                        android:textColor="@color/colorPrimaryText"
                        android:textColorHint="@color/colorSilver"
                      />

                </android.support.design.widget.TextInputLayout>

                <View
                    android:id="@+id/right_button"
                    android:layout_width="24dp"
                    android:layout_height="24dp"
                    android:layout_centerVertical="true"
                    android:layout_alignParentEnd="true"
                    android:layout_marginEnd="12dp"
                    android:background="@color/clear" />
            </RelativeLayout>

非常非常好，感谢所有参与讨论的人。因此，如果你不想处理扩展类带来的不便，你可以执行以下操作(仅为正确的可绘制对象实现)

this.keyword = (AutoCompleteTextView) findViewById(R.id.search);
this.keyword.setOnTouchListener(new RightDrawableOnTouchListener(keyword) {
        @Override
        public boolean onDrawableTouch(final MotionEvent event) {
            return onClickSearch(keyword,event);
        }
    });

private boolean onClickSearch(final View view, MotionEvent event) {
    // do something
    event.setAction(MotionEvent.ACTION_CANCEL);
    return false;
}

下面是基于@Mark的回答的基本侦听器实现

public abstract class RightDrawableOnTouchListener implements OnTouchListener {
    Drawable drawable;
    private int fuzz = 10;

    /**
     * @param keyword
     */
    public RightDrawableOnTouchListener(TextView view) {
        super();
        final Drawable[] drawables = view.getCompoundDrawables();
        if (drawables != null && drawables.length == 4)
            this.drawable = drawables[2];
    }

    /*
     * (non-Javadoc)
     * 
     * @see android.view.View.OnTouchListener#onTouch(android.view.View, android.view.MotionEvent)
     */
    @Override
    public boolean onTouch(final View v, final MotionEvent event) {
        if (event.getAction() == MotionEvent.ACTION_DOWN && drawable != null) {
            final int x = (int) event.getX();
            final int y = (int) event.getY();
            final Rect bounds = drawable.getBounds();
            if (x >= (v.getRight() - bounds.width() - fuzz) && x <= (v.getRight() - v.getPaddingRight() + fuzz)
                    && y >= (v.getPaddingTop() - fuzz) && y <= (v.getHeight() - v.getPaddingBottom()) + fuzz) {
                return onDrawableTouch(event);
            }
        }
        return false;
    }

    public abstract boolean onDrawableTouch(final MotionEvent event);

}

这是我的简单解决方案，只是把ImageButton放在EditText上:

<RelativeLayout
  android:layout_width="match_parent"
  android:layout_height="wrap_content">

  <EditText android:id="@+id/editTextName"
    android:layout_width="fill_parent"
    android:layout_height="wrap_content"
    android:imeOptions="actionSearch"
    android:inputType="text"/>

  <ImageButton android:id="@+id/imageViewSearch"
    android:layout_width="wrap_content"
    android:layout_height="wrap_content"
    android:src="@drawable/ic_action_search"
    android:layout_alignParentRight="true"
    android:layout_centerVertical="true"/>

</RelativeLayout>

//单击右图标

editText.setOnTouchListener(new View.OnTouchListener() {
            @Override
            public boolean onTouch(View v, MotionEvent event) {
                final int DRAWABLE_RIGHT = 2;

                if(event.getAction() == MotionEvent.ACTION_UP) {
                    if(event.getRawX() >= (createEventBinding.etAddressLine1.getRight() - createEventBinding.etAddressLine1.getCompoundDrawables()[DRAWABLE_RIGHT].getBounds().width())) {
                        // your action here

                        Toast.makeText(getActivity(), "Right icon click", Toast.LENGTH_SHORT).show();

                        return true;
                    }
                }
                return false;
            }
        });

最好在编辑文本的右边有ImageButton，并给负布局边距与编辑文本重叠。在ImageButton上设置监听器并执行操作。