我是如何让它工作的:

virtualenv -p python3.5 env/test

在找到我的环境后:

pip install pymysql
pip install django

然后，我运行startproject，在manage.py中，我添加了这个:

+ try:
+     import pymysql
+     pymysql.install_as_MySQLdb()
+ except:
+     pass

同时，更新了内部设置:

DATABASES = {
    'default': {
        'ENGINE': 'django.db.backends.mysql',
        'NAME': 'foobar_db',
        'USER': 'foobaruser',
        'PASSWORD': 'foobarpwd',
    }
}

我也有configparser==3.5.0安装在我的virtualenv，不确定这是否是必需的…

希望能有所帮助，

我通过使用pip安装MySQL-python库克服了同样的问题。当我第一次在settings.py中更改数据库设置并执行makemigrations命令时，您可以看到控制台上显示的消息(解决方案如下消息所示，请参阅)。

  (vir_env) admins-MacBook-Pro-3:src admin$ python manage.py makemigrations
Traceback (most recent call last):
  File "manage.py", line 10, in <module>
    execute_from_command_line(sys.argv)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/core/management/__init__.py", line 338, in execute_from_command_line
    utility.execute()
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/core/management/__init__.py", line 312, in execute
    django.setup()
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/__init__.py", line 18, in setup
    apps.populate(settings.INSTALLED_APPS)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/apps/registry.py", line 108, in populate
    app_config.import_models(all_models)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/apps/config.py", line 198, in import_models
    self.models_module = import_module(models_module_name)
  File "/usr/local/Cellar/python/2.7.12_1/Frameworks/Python.framework/Versions/2.7/lib/python2.7/importlib/__init__.py", line 37, in import_module
    __import__(name)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/contrib/auth/models.py", line 41, in <module>
    class Permission(models.Model):
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/models/base.py", line 139, in __new__
    new_class.add_to_class('_meta', Options(meta, **kwargs))
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/models/base.py", line 324, in add_to_class
    value.contribute_to_class(cls, name)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/models/options.py", line 250, in contribute_to_class
    self.db_table = truncate_name(self.db_table, connection.ops.max_name_length())
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/__init__.py", line 36, in __getattr__
    return getattr(connections[DEFAULT_DB_ALIAS], item)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/utils.py", line 240, in __getitem__
    backend = load_backend(db['ENGINE'])
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/utils.py", line 111, in load_backend
    return import_module('%s.base' % backend_name)
  File "/usr/local/Cellar/python/2.7.12_1/Frameworks/Python.framework/Versions/2.7/lib/python2.7/importlib/__init__.py", line 37, in import_module
    __import__(name)
  File "/Users/admin/Desktop/SetUp1/vir_env/lib/python2.7/site-packages/django/db/backends/mysql/base.py", line 27, in <module>
    raise ImproperlyConfigured("Error loading MySQLdb module: %s" % e)
django.core.exceptions.ImproperlyConfigured: Error loading MySQLdb module: No module named MySQLdb

最终我克服了这个问题:

(vir_env) admins-MacBook-Pro-3:src admin$ pip install MySQLdb
Collecting MySQLdb
  Could not find a version that satisfies the requirement MySQLdb (from versions: )
No matching distribution found for MySQLdb
(vir_env) admins-MacBook-Pro-3:src admin$ pip install MySQL-python
Collecting MySQL-python
  Downloading MySQL-python-1.2.5.zip (108kB)
    100% |████████████████████████████████| 112kB 364kB/s 
Building wheels for collected packages: MySQL-python
  Running setup.py bdist_wheel for MySQL-python ... done
  Stored in directory: /Users/admin/Library/Caches/pip/wheels/38/a3/89/ec87e092cfb38450fc91a62562055231deb0049a029054dc62
Successfully built MySQL-python
Installing collected packages: MySQL-python
Successfully installed MySQL-python-1.2.5
(vir_env) admins-MacBook-Pro-3:src admin$ python manage.py makemigrations
No changes detected
(vir_env) admins-MacBook-Pro-3:src admin$ python manage.py migrate
Operations to perform:
  Synchronize unmigrated apps: staticfiles, rest_framework, messages, crispy_forms
  Apply all migrations: admin, contenttypes, sessions, auth, PyApp
Synchronizing apps without migrations:
  Creating tables...
    Running deferred SQL...
  Installing custom SQL...
Running migrations:
  Rendering model states... DONE
  Applying PyApp.0001_initial... OK
  Applying PyApp.0002_auto_20170310_0936... OK
  Applying PyApp.0003_auto_20170310_0953... OK
  Applying PyApp.0004_auto_20170310_0954... OK
  Applying PyApp.0005_auto_20170311_0619... OK
  Applying PyApp.0006_auto_20170311_0622... OK
  Applying PyApp.0007_loraevksensor... OK
  Applying PyApp.0008_auto_20170315_0752... OK
  Applying PyApp.0009_auto_20170315_0753... OK
  Applying PyApp.0010_auto_20170315_0806... OK
  Applying PyApp.0011_auto_20170315_0814... OK
  Applying PyApp.0012_auto_20170315_0820... OK
  Applying PyApp.0013_auto_20170315_0822... OK
  Applying PyApp.0014_auto_20170315_0907... OK
  Applying PyApp.0015_auto_20170315_1041... OK
  Applying PyApp.0016_auto_20170315_1355... OK
  Applying PyApp.0017_auto_20170315_1401... OK
  Applying PyApp.0018_auto_20170331_1348... OK
  Applying PyApp.0019_auto_20170331_1349... OK
  Applying PyApp.0020_auto_20170331_1350... OK
  Applying PyApp.0021_auto_20170331_1458... OK
  Applying PyApp.0022_delete_postoffice... OK
  Applying PyApp.0023_posoffice... OK
  Applying PyApp.0024_auto_20170331_1504... OK
  Applying PyApp.0025_auto_20170331_1511... OK
  Applying contenttypes.0001_initial... OK
  Applying auth.0001_initial... OK
  Applying admin.0001_initial... OK
  Applying contenttypes.0002_remove_content_type_name... OK
  Applying auth.0002_alter_permission_name_max_length... OK
  Applying auth.0003_alter_user_email_max_length... OK
  Applying auth.0004_alter_user_username_opts... OK
  Applying auth.0005_alter_user_last_login_null... OK
  Applying auth.0006_require_contenttypes_0002... OK
  Applying sessions.0001_initial... OK
(vir_env) admins-MacBook-Pro-3:src admin$ 

运行Ubuntu 13.10 64位时，以下操作对我来说非常有效:

sudo apt-get install libmysqlclient-dev
sudo apt-get install python-dev

现在，导航到你的virtualenv(例如env文件夹)并执行以下命令:

sudo ./bin/pip install mysql-python

实际上，我在一个单独的问题中找到了解决方案，下面引用它:

If you have created the virtualenv with the --no-site-packages switch (the default), then system-wide installed additions such as MySQLdb are not included in the virtual environment packages. You need to install MySQLdb with the pip command installed with the virtualenv. Either activate the virtualenv with the bin/activate script, or use bin/pip from within the virtualenv to install the MySQLdb library locally as well. Alternatively, create a new virtualenv with system site-packages included by using the --system-site-package switch.

我认为这也适用于OSX。唯一的问题是获得用于安装libmysqlclient-dev和python-dev的等效命令，因为它们需要编译 我猜是mysql-python。

希望这能有所帮助。

此问题是由于MySQL for Python适配器安装不完整/不正确造成的。具体来说，我必须编辑mysql_config文件的路径，使其指向/usr/local/mysql/bin/mysql_config——本文将更详细地讨论:http://dakrauth.com/blog/entry/python-and-django-setup-mac-os-x-leopard/

我也有同样的错误，pip install MySQL-python为我解决了这个问题。

备选安装:

如果没有pip, easy_install MySQL-python应该可以工作。 如果你的python是由打包系统管理的，你可能不得不使用 该系统(例如sudo apt-get install…)

下面，Soli指出，如果你收到以下错误:

mysql_config未找到

．.． 然后还有一个进一步的系统依赖问题。解决方法因系统而异，但对于debian衍生系统:

使用apt-get install python-mysqldb

运行Ubuntu，我必须做:

sudo apt-get install python-mysqldb