使用BufferedReader，但函数应该是异步的:

var load = function (file, cb){
    var lines = [];
    new BufferedReader (file, { encoding: "utf8" })
        .on ("error", function (error){
            cb (error, null);
        })
        .on ("line", function (line){
            lines.push (line);
        })
        .on ("end", function (){
            cb (null, lines);
        })
        .read ();
};

load ("file", function (error, lines){
    if (error) return console.log (error);
    console.log (lines);
});

使用readline(文档)。下面是一个例子，读取一个CSS文件，解析图标并将它们写入json

var results = [];
  var rl = require('readline').createInterface({
    input: require('fs').createReadStream('./assets/stylesheets/_icons.scss')
  });


  // for every new line, if it matches the regex, add it to an array
  // this is ugly regex :)
  rl.on('line', function (line) {
    var re = /\.icon-icon.*:/;
    var match;
    if ((match = re.exec(line)) !== null) {
      results.push(match[0].replace(".",'').replace(":",''));
    }
  });


  // readline emits a close event when the file is read.
  rl.on('close', function(){
    var outputFilename = './icons.json';
    fs.writeFile(outputFilename, JSON.stringify(results, null, 2), function(err) {
        if(err) {
          console.log(err);
        } else {
          console.log("JSON saved to " + outputFilename);
        }
    });
  });

我只是想添加@finbarr伟大的答案，在异步的例子中的一个小修复:

异步:

var fs = require('fs');
fs.readFile('file.txt', function(err, data) {
    if(err) throw err;
    var array = data.toString().split("\n");
    for(i in array) {
        console.log(array[i]);
    }
    done();
});

@ madphysics, done()释放async。调用。

同步:

var fs = require('fs');
var array = fs.readFileSync('file.txt').toString().split("\n");
for(i in array) {
    console.log(array[i]);
}

异步:

var fs = require('fs');
fs.readFile('file.txt', function(err, data) {
    if(err) throw err;
    var array = data.toString().split("\n");
    for(i in array) {
        console.log(array[i]);
    }
});

js:

var array = fs.readFileSync('file.txt', 'utf8').split('\n');

ts:

var array = fs.readFileSync('file.txt', 'utf8').toString().split('\n');

使用Node.js的readline模块。

var fs = require('fs');
var readline = require('readline');

var filename = process.argv[2];
readline.createInterface({
    input: fs.createReadStream(filename),
    terminal: false
}).on('line', function(line) {
   console.log('Line: ' + line);
});