如果你正在构建DEBUG APK，只需添加:

debug {
            multiDexEnabled true
        }

内部buildTypes

如果你正在构建RELEASE APK，添加 释放块multiDexEnabled为true为-

release {
                ...
                multiDexEnabled true
                ...
        }

如果你使用Dagger:

public class App extends DaggerApplication {

    @Override
    protected void attachBaseContext(Context base) {
        super.attachBaseContext(base);
        MultiDex.install(this); //ADD MULTIDEX HERE!!!
    }

    @Override
    protected AndroidInjector<? extends DaggerApplication> applicationInjector() {
        return DaggerAppComponent.builder().application(this).build();
    }
}

在应用程序构建中。gradle文件:

android {
        defaultConfig {
            ...
            multiDexEnabled true
        }
    }
 ...
 implementation 'com.android.support:multidex:1.0.3'

只需将此代码添加到应用程序或模块的build.gradle中即可

android {
    defaultConfig {
        ...
        
        multiDexEnabled true <------ * here
    }
    ...
}

只需要做以下几点:

build.gradle

(module:app)


android {
            ....
      defaultConfig {
              multiDexEnabled true // enable mun
      }
}

并在构建中添加以下依赖项。Gradle应用程序级别文件

dependencies {
    implementation 'com.android.support:multidex:1.0.3'
} 

如果你在Proguard中使用minifyEnabled，你可能不需要启用multi-dex。我同意MG Developer的观点，如果可能的话，你应该尽量避免使用多重索引。我的解决方案是只对调试版本启用multi-dex。minifyEnabled解决了发布版本的问题

buildTypes {
    release {
        minifyEnabled true
        proguardFiles getDefaultProguardFile('proguard-android.txt'), 'proguard-rules.pro'
    }
    debug {
        // getting error: Cannot fit requested classes in a single dex file.  # methods: 65537 > 65536
        // https://developer.android.com/studio/build/multidex
        // minifyEnabled true (used with release) will fix this by getting rid of unused method calls, but this will hide debugging info on crash
        multiDexEnabled true
    }
}

修改应用程序或模块的build.gradle

android {
    defaultConfig {
        ...
        minSdkVersion 21 <----- *here
        targetSdkVersion 26
        multiDexEnabled true <------ *here
    }
    ...
}

根据官方文件

Multidex support for Android 5.0 and higher Android 5.0 (API level 21) and higher uses a runtime called ART which natively supports loading multiple DEX files from APK files. ART performs pre-compilation at app install time which scans for classesN.dex files and compiles them into a single .oat file for execution by the Android device. Therefore, if your minSdkVersion is 21 or higher, you do not need the multidex support library. For more information on the Android 5.0 runtime, read ART and Dalvik.

https://developer.android.com/studio/build/multidex