对于我的项目，我仍然需要支持IE7和工作大输入编码。

根据Joe Dyndale提出的代码和Marius在评论中提出的建议，可以通过使用数组而不是字符串构造结果来提高IE7的性能。

下面是encode的例子:

var encode = function (input) {
    var output = [], chr1, chr2, chr3, enc1, enc2, enc3, enc4, i = 0;

    input = _utf8_encode(input);

    while (i < input.length) {

        chr1 = input.charCodeAt(i++);
        chr2 = input.charCodeAt(i++);
        chr3 = input.charCodeAt(i++);

        enc1 = chr1 >> 2;
        enc2 = ((chr1 & 3) << 4) | (chr2 >> 4);
        enc3 = ((chr2 & 15) << 2) | (chr3 >> 6);
        enc4 = chr3 & 63;

        if (isNaN(chr2)) {
            enc3 = enc4 = 64;
        } else if (isNaN(chr3)) {
            enc4 = 64;
        }

        output.push(_keyStr.charAt(enc1));
        output.push(_keyStr.charAt(enc2));
        output.push(_keyStr.charAt(enc3));
        output.push(_keyStr.charAt(enc4));

    }

    return output.join("");
};

这是一个缩小的填充窗口。Atob + window.btoa:

(function(){function t(t){this.message=t}var e="undefined"!=typeof exports?exports:this,r="ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=";t.prototype=Error(),t.prototype.name="InvalidCharacterError",e.btoa||(e.btoa=function(e){for(var o,n,a=0,i=r,c="";e.charAt(0|a)||(i="=",a%1);c+=i.charAt(63&o>>8-8*(a%1))){if(n=e.charCodeAt(a+=.75),n>255)throw new t("'btoa' failed: The string to be encoded contains characters outside of the Latin1 range.");o=o<<8|n}return c}),e.atob||(e.atob=function(e){if(e=e.replace(/=+$/,""),1==e.length%4)throw new t("'atob' failed: The string to be decoded is not correctly encoded.");for(var o,n,a=0,i=0,c="";n=e.charAt(i++);~n&&(o=a%4?64*o+n:n,a++%4)?c+=String.fromCharCode(255&o>>(6&-2*a)):0)n=r.indexOf(n);return c})})();

(function (root, factory) {
    if (typeof define === 'function' && define.amd) {
        // AMD. Register as an anonymous module.
        define([], function() {factory(root);});
    } else factory(root);
// node.js has always supported base64 conversions, while browsers that support
// web workers support base64 too, but you may never know.
})(typeof exports !== "undefined" ? exports : this, function(root) {
    if (root.atob) {
        // Some browsers' implementation of atob doesn't support whitespaces
        // in the encoded string (notably, IE). This wraps the native atob
        // in a function that strips the whitespaces.
        // The original function can be retrieved in atob.original
        try {
            root.atob(" ");
        } catch(e) {
            root.atob = (function(atob) {
                var func = function(string) {
                    return atob(String(string).replace(/[\t\n\f\r ]+/g, ""));
                };
                func.original = atob;
                return func;
            })(root.atob);
        }
        return;
    }

        // base64 character set, plus padding character (=)
    var b64 = "ABCDEFGHIJKLMNOPQRSTUVWXYZabcdefghijklmnopqrstuvwxyz0123456789+/=",
        // Regular expression to check formal correctness of base64 encoded strings
        b64re = /^(?:[A-Za-z\d+\/]{4})*?(?:[A-Za-z\d+\/]{2}(?:==)?|[A-Za-z\d+\/]{3}=?)?$/;

    root.btoa = function(string) {
        string = String(string);
        var bitmap, a, b, c,
            result = "", i = 0,
            rest = string.length % 3; // To determine the final padding

        for (; i < string.length;) {
            if ((a = string.charCodeAt(i++)) > 255
                    || (b = string.charCodeAt(i++)) > 255
                    || (c = string.charCodeAt(i++)) > 255)
                throw new TypeError("Failed to execute 'btoa' on 'Window': The string to be encoded contains characters outside of the Latin1 range.");

            bitmap = (a << 16) | (b << 8) | c;
            result += b64.charAt(bitmap >> 18 & 63) + b64.charAt(bitmap >> 12 & 63)
                    + b64.charAt(bitmap >> 6 & 63) + b64.charAt(bitmap & 63);
        }

        // If there's need of padding, replace the last 'A's with equal signs
        return rest ? result.slice(0, rest - 3) + "===".substring(rest) : result;
    };

    root.atob = function(string) {
        // atob can work with strings with whitespaces, even inside the encoded part,
        // but only \t, \n, \f, \r and ' ', which can be stripped.
        string = String(string).replace(/[\t\n\f\r ]+/g, "");
        if (!b64re.test(string))
            throw new TypeError("Failed to execute 'atob' on 'Window': The string to be decoded is not correctly encoded.");

        // Adding the padding if missing, for semplicity
        string += "==".slice(2 - (string.length & 3));
        var bitmap, result = "", r1, r2, i = 0;
        for (; i < string.length;) {
            bitmap = b64.indexOf(string.charAt(i++)) << 18 | b64.indexOf(string.charAt(i++)) << 12
                    | (r1 = b64.indexOf(string.charAt(i++))) << 6 | (r2 = b64.indexOf(string.charAt(i++)));

            result += r1 === 64 ? String.fromCharCode(bitmap >> 16 & 255)
                    : r2 === 64 ? String.fromCharCode(bitmap >> 16 & 255, bitmap >> 8 & 255)
                    : String.fromCharCode(bitmap >> 16 & 255, bitmap >> 8 & 255, bitmap & 255);
        }
        return result;
    };
});

完整版https://github.com/MaxArt2501/base64-js/blob/master/base64.js

我宁愿使用CryptoJS中的Base64编码/解码方法，这是使用最佳实践和模式在JavaScript中实现的最流行的标准和安全加密算法库。

这是一个atob()和btoa() JavaScript内置函数的现场演示:

<!DOCTYPE html>
<html>
  <head>
    <style>
      textarea{
        width:30%;
        height:100px;
      }
    </style>
    <script>
      // encode string to base64
      function encode()
      {
        var txt = document.getElementById("txt1").value;
        var result = btoa(txt);
        document.getElementById("txt2").value = result;
      }
      // decode base64 back to original string
      function decode()
      {
        var txt = document.getElementById("txt3").value;
        var result = atob(txt);
        document.getElementById("txt4").value = result;
      }
    </script>
  </head>
  <body>
    <div>
      <textarea id="txt1">Some text to decode
      </textarea>
    </div>
    <div>
      <input type="button" id="btnencode" value="Encode" onClick="encode()"/>
    </div>
    <div>
      <textarea id="txt2">
      </textarea>
    </div>
    <br/>
    <div>
      <textarea id="txt3">U29tZSB0ZXh0IHRvIGRlY29kZQ==
      </textarea>
    </div>
    <div>
      <input type="button" id="btndecode" value="Decode" onClick="decode()"/>
    </div>
    <div>
      <textarea id="txt4">
      </textarea>
    </div>
  </body>
</html>

这个问题和它的答案为我指明了正确的方向。 特别是Unicode, atob和btoa不能“香草”使用，这些天所有的东西都是Unicode…

直接来自Mozilla的两个很好的函数。 使用Unicode和HTML标签进行测试:

function b64EncodeUnicode(str) {
    return btoa(encodeURIComponent(str).replace(/%([0-9A-F]{2})/g, function(match, p1) {
        return String.fromCharCode('0x' + p1);
    }));
}

b64EncodeUnicode('✓ à la mode'); // "4pyTIMOgIGxhIG1vZGU="
b64EncodeUnicode('\n'); // "Cg=="


function b64DecodeUnicode(str) {
    return decodeURIComponent(Array.prototype.map.call(atob(str), function(c) {
        return '%' + ('00' + c.charCodeAt(0).toString(16)).slice(-2);
    }).join(''));
}

b64DecodeUnicode('4pyTIMOgIGxhIG1vZGU='); // "✓ à la mode"
b64DecodeUnicode('Cg=='); // "\n"

与使用自定义JavaScript函数的原始Base64解码相比，这些函数将以闪电般的速度执行，因为btoa和atob在解释器外部执行。

如果你可以忽略旧的ie浏览器和旧的手机(比如iPhone 3?)，这应该是一个很好的解决方案。

我需要一个UTF-8字符串编码为Base64为我的一个项目。这里的大多数答案似乎在转换为UTF-8时不能正确处理UTF-16代理对，因此，为了完成，我将发布我的解决方案:

function strToUTF8Base64(str) {

    function decodeSurrogatePair(hi, lo) {
        var resultChar = 0x010000;
        resultChar += lo - 0xDC00;
        resultChar += (hi - 0xD800) << 10;
        return resultChar;
    }

    var bytes = [0, 0, 0];
    var byteIndex = 0;
    var result = [];

    function output(s) {
        result.push(s);
    }

    function emitBase64() {

        var digits =
                'ABCDEFGHIJKLMNOPQRSTUVWXYZ' +
                'abcdefghijklmnopqrstuvwxyz' +
                '0123456789+/';

        function toDigit(value) {
            return digits[value];
        }

        // --Byte 0--    --Byte 1--    --Byte 2--
        // 1111  1122    2222  3333    3344  4444

        var d1 = toDigit(bytes[0] >> 2);
        var d2 = toDigit(
            ((bytes[0] & 0x03) << 4) |
            (bytes[1] >> 4));
        var d3 = toDigit(
            ((bytes[1] & 0x0F) << 2) |
            (bytes[2] >> 6));
        var d4 = toDigit(
            bytes[2] & 0x3F);

        if (byteIndex === 1) {
            output(d1 + d2 + '==');
        }
        else if (byteIndex === 2) {
            output(d1 + d2 + d3 + '=');
        }
        else {
            output(d1 + d2 + d3 + d4);
        }
    }

    function emit(chr) {
        bytes[byteIndex++] = chr;
        if (byteIndex == 3) {
            emitBase64();
            bytes[0] = 0;
            bytes[1] = 0;
            bytes[2] = 0;
            byteIndex = 0;
        }
    }

    function emitLast() {
        if (byteIndex > 0) {
            emitBase64();
        }
    }

    // Converts the string to UTF8:

    var i, chr;
    var hi, lo;
    for (i = 0; i < str.length; i++) {
        chr = str.charCodeAt(i);

        // Test and decode surrogate pairs in the string
        if (chr >= 0xD800 && chr <= 0xDBFF) {
            hi = chr;
            lo = str.charCodeAt(i + 1);
            if (lo >= 0xDC00 && lo <= 0xDFFF) {
                chr = decodeSurrogatePair(hi, lo);
                i++;
            }
        }

        // Encode the character as UTF-8.
        if (chr < 0x80) {
            emit(chr);
        }
        else if (chr < 0x0800) {
            emit((chr >> 6) | 0xC0);
            emit(((chr >> 0) & 0x3F) | 0x80);
        }
        else if (chr < 0x10000) {
            emit((chr >> 12) | 0xE0);
            emit(((chr >>  6) & 0x3F) | 0x80);
            emit(((chr >>  0) & 0x3F) | 0x80);
        }
        else if (chr < 0x110000) {
            emit((chr >> 18) | 0xF0);
            emit(((chr >> 12) & 0x3F) | 0x80);
            emit(((chr >>  6) & 0x3F) | 0x80);
            emit(((chr >>  0) & 0x3F) | 0x80);
        }
    }

    emitLast();

    return result.join('');
}

注意，代码没有经过彻底的测试。我测试了一些输入，包括strToUTF8Base64('衠衢蠩蠨')，并将其与在线编码工具(https://www.base64encode.org/)的输出进行了比较。