下面是我用来获取给定字符串的MD5的代码片段:

$text = "text goes here..."
$md5  = [Security.Cryptography.MD5CryptoServiceProvider]::new()
$utf8 = [Text.UTF8Encoding]::UTF8
$bytes= $md5.ComputeHash($utf8.GetBytes($text))
$hash = [string]::Concat($bytes.foreach{$_.ToString("x2")}) 

如果你正在使用PowerShell社区扩展，有一个Get-Hash命令可以很容易地做到这一点:

C:\PS> "hello world" | Get-Hash -Algorithm MD5


Algorithm: MD5


Path       :
HashString : E42B054623B3799CB71F0883900F2764

这将返回远程计算机上文件的MD5哈希值:

Invoke-Command -ComputerName RemoteComputerName -ScriptBlock {
    $fullPath = Resolve-Path 'c:\Program Files\Internet Explorer\iexplore.exe'
    $md5 = new-object -TypeName System.Security.Cryptography.MD5CryptoServiceProvider
    $file = [System.IO.File]::OpenRead($fullPath)
    $hash = [System.BitConverter]::ToString($md5.ComputeHash($file))
    $hash -replace "-", ""
    $file.Dispose()
}

正如已接受的答案中所述，Get-FileHash很容易用于文件，但也可以用于字符串:

$s = "asdf"
Get-FileHash -InputStream ([System.IO.MemoryStream]::New([System.Text.Encoding]::ASCII.GetBytes($s)))

下面是我使用的处理相对路径和绝对路径的函数:

function md5hash($path)
{
    $fullPath = Resolve-Path $path
    $md5 = new-object -TypeName System.Security.Cryptography.MD5CryptoServiceProvider
    $file = [System.IO.File]::Open($fullPath,[System.IO.Filemode]::Open, [System.IO.FileAccess]::Read)
    try {
        [System.BitConverter]::ToString($md5.ComputeHash($file))
    } finally {
        $file.Dispose()
    }
}

感谢@davor上面建议使用Open()而不是ReadAllBytes()，并感谢@jpmc26建议使用finally块。

(
    [System.Security.Cryptography.MD5CryptoServiceProvider]::new().ComputeHash(
        [System.Text.UTF8Encoding]::new().GetBytes($yourText)
    ) `
    | %{ [Convert]::ToString($_, 16) }
) -join ''

$yourText = 'hello'输出5d41402abc4b2a76b9719d911017c592